Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 65 for “"C. jejuni"”.
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Identification and characterization of virulence associated factors of C. jejuni
Campylobacter jejuni, an important food-borne human bacterial pathogen in industrialized countries and in the developing world, the leading cause of bacterial diarrhoea. The infection may be accompanied by fever and abdominal cramps and, as a post-infection complication, in rare cases …
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Die funktionelle Relevanz humoraler und zellulärer Immunreaktionen gegen Campylobacter jejuni in der Pathogenese von Immunneuropathien
… mögliche Pathomechanismen einer Campylobacter jejuni-spezifischen Immunantwort bei der Entstehung akuter Immunneuropathien wurden untersucht. Neben anderen wurden für die Untersuchungen auch C. jejuni-Stämme eingesetzt, welche von Guillain-Barré- (GBS) und Miller-Fisher-syndrome (MFS) Patienten …
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The role of biofilms in Campylobacter jejuni survival in the food chain
Campylobacter jejuni is the leading cause of bacterial foodborne poisoning in the developed world. The impact of infection is mainly economic, however the disease can lead to severe post infection complications, such as Guillain–Barré syndrome. Despite the fastidious nature of C. jejuni, it is able …
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Genome sequence of the hyperinvasive Campylobacter jejuni strains
Campylobacter jejuni is the world’s major cause of gastroenteritis in humans. Although motility, toxin production, adhesion and invasion are some of the key factors associated with C. jejuni pathogenesis, their mechanism in the disease process remains unclear. The key aim of this project is to …
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Analysis of Bacterial-Host Interactions Between Campylobacter jejuni and the Avian Host During Commensalism
Campylobacter jejuni is a leading cause of bacterial enteritis in humans throughout the world. In contrast to the disease seen in humans upon infection, C. jejuni promotes an asymptomatic, intestinal colonization of many animals, especially avian species, to result in commensalism. The primary …
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Effect of incubation temperature and composition of brucella agar on growth of Campylobacter jejuni
Aerotolerance of Campylobacter jejuni ATCC 29428 and one of its aerotolerant mutants (strain MC711-01) was measured at 37°C and 42°C. The aerotolerance of C. jejuni was higher at 42°C than at 37°C. Three different lots of Gibco dehydrated Brucella broth were used to prepare Brucella agar. The agar …
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Signals and Sensory Mechanisms that Impact Campylobacter jejuni-Host Interactions
Campylobacter jejuni is a leading cause of bacterial diarrheal disease worldwide and a frequent commensal organism of the intestinal tract of poultry and other agriculturally-important animals. Upon infection of the avian host, C. jejuni likely responds to external stimuli present within the …
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Regulating Campylobacter jejuni flagellar gene expression: transcriptional and post-transcriptional mechanisms of control
The bacterial pathogen Campylobacter jejuni is the leading cause of foodborne gastroenteritis in the developed world. C. jejuni flagella are crucial virulence determinants, but the regulation of these complex organelles within different environments is not fully understood. Moreover, regulatory …
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Characterisation of the lipooligosaccharide biosynthesis gene cluster in campylobacter species
… (1-4) with 23 classes (A-W) for Campylobacter jejuni (C. jejuni) LOS region. The aim of this work was to characterise the C. jejuni and C. coli LOS biosynthesis loci with special emphasis on their classes’ distribution and also to determine the role of LOS in mediating the host immune response. …
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The coaggregative abilities of lactobacilli and Campylobacter jejuni
Campylobacter jejuni is a pathogen commonly found in poultry that is one of the main bacterial causes of foodborne diarrheal disease in humans. The aim of this study was to analyze the coaggregative abilities of lactic acid bacteria and C. jejuni as a means to reduce the colonization of C. jejuni …
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Niche-adaptive evolution in Campylobacter jejuni
Campylobacter jejuni is the leading causative agent of human bacterial gastroenteritis. Human C. jejuni infection (campylobacteriosis) is frequently associated with poultry; through consumption of undercooked products, cross contamination from raw meats, or through direct contact with birds or …
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Prevalence and Dissemination of Antimicrobial Resistance among Campylobacter jejuni and Campylobacter coli from Meat-Animals
Campylobacter jejuni and C. coli from conventionally grown turkeys have been frequently reported to be resistant to nalidixic acid and ciprofloxacin. To reduce possible contributions of fluoroquinolone use in poultry production to fluoroquinolone resistance in poultry-derived Campylobacter, use of …
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Development and validation of a CRISPR interference system for gene regulation in Campylobacter jejuni
… illness in humans worldwide, with Campylobacter jejuni responsible for 80% of these infections. There is an urgent need to understand fundamental C. jejuni biology for the development of new strategies to prevent and treat infections. The range of molecular tools available to regulate gene …
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Comparative Phenotypic and Transcriptional Differences of Campylobacter jejuni When Challenged with Low Molecular Weight Chitosan
Campylobacter jejuni is a prominent food-borne pathogen and causative agent of Campylobacteriosis infection. This infection arises primarily from the consumption of foodstuffs/beverages previously contaminated with this microorganism. Despite current food control measures currently employed, this …
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Lactobacillus strategies to reduce Campylobacter jejuni colonization of broiler chickens
Campylobacter jejuni is one of the leading causes of foodborne bacterial illness in the world. The majority of cases of campylobacteriosis are associated with the consumption of raw or undercooked poultry meat or their cross-contamination with other food products. Strategies to reduce the presence …
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The significance of strain diversity in the epidemiology of Camplobacter jejuni gastrointestinal infections
… diversity in a collection of Campylobacterjejuni isolates involved in human disease and from animal and environmental sources was undertakert Isolates were characterised by phenotype, using heat stable antigen serotype, bacteriophage type and biotyping methods. Isolates were also genotyped …
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Oxidative stress responses in Campylobacter jejuni: the role of the Peroxide Regulator PerR
Campylobacter jejuni is a microaerophilic foodborne pathogen capable of surviving the stressful, oxygen-exposed route from an avian host and entering into the human food chain. The ability of Campylobacter to survive oxidative stress is thought to contribute to the annual ~500,000 UK cases of …
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Genotyping and antibiotic resistance of thermophilic Campylobacter isolates from Vietnam and Kenya
… of isolates (Chapter 2). Nine isolates (eight C. jejuni and one C. coli) isolated from meat were identified by multiplex PCR, and tested for the presence or absence of 29 gene loci associated with virulence, lipooligosaccharide (LOS) biosynthesis and further functions. flaA typing, multilocus …
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Development of comparative genomic fingerprinting for molecular epidemiological studies of Campylobacter jejuni
… a rapid genotyping method for Campylobacter jejuni that assesses the conservation status of 20 genes previously described as having high intraspecies variability based on comparative genomics studies. This novel method for genotyping C. jejuni, CGF was validated two-fold. First, by comparison …
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Efficacy of Delmopinol in Preventing the Attachment of Campylobacter jejuni to Chicken, Stainless Steel and High-Density Polyethylene
… for reducing attachment of Campylobacter jejuni to chicken, stainless steel and high-density polyethylene. Chicken pieces, steel and HDPE coupons were spot-inoculated with 0.1 mL of a Campylobacter jejuni culture. After 10 min, samples were sprayed with 0.5% or 1.0% delmopinol, 0.01% …
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