Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"C. botulinum"”.
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Engineering functional recombinant proteins based on antibody domains and fragments of C. botulinum neurotoxin
… and single domain antibodies. Recombinant botulinum neurotoxin fragments derived from serotype A, B, C and D are selected as backbones for an investigation into the feasibility and properties of novel recombinant targeted multidomain proteins. Single chain Fv’s consist of a VH region of …
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Transmembranäre Proteintransportsysteme an kultivierten Säugerzellen: Chimären cer C2-Ribosyltransferase von C. botulinum und Streptolysin O
… sowie die ADP-Ribosyltransferase-Domäne des C. botulinum-C2-Toxins mit Hilfe eines bakteriellen Transporters in eukaryonte Zielzellen eingebracht werden können (C2II, die Bindungs- und Translokationskomponente des binären C2-Toxins, bzw. mit dem porenbildenden Streptolysin O (SLO)). Dazu wurden …
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The inhibition of Clostridium botulinum growth and toxin production by essential oils of spices
… outgrowth, growth, and toxin production of C. botulinum strains in microbiological media. The oils of clove, thyme, origanum, and cinnamon were studied for their mechanism of inhibition of C. botulinum 67B. The most effective oil, in combination with sodium nitrite at different levels was …
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Impact of strain variability on the risk presented to chilled foods by non-proteolytic clostridium botulinum
… on variability of non-proteolytic Clostridium botulinum at strain level. The research on strain variability covers practical experiments as well as literature surveys and focuses on heat resistance properties of non-proteolytic C. botulinum spores, variability in growth at chill temperatures …
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Real-time PCR for diagnosis of botulism and quantification of neurotoxin gene expression in Clostridium botulinum
… methods for (i) detection of Clostridium botulinum in food and clinical samples, and (ii) monitoring the expression of the neurotoxin gene, cnt, during different growth phases and under different growth conditions. For the diagnosis of botulism, a real-time PCR-based method including an …
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Plasmids in Clostridium botulinum type A and Clostridium sporogenes
A procedure to rapidly screen Clostridium botulinum type A and Clostridium sporogenes for plasmids was developed. Plasmid profiles of five C. botulinum type A strains and seven C. sporogenes strains were determined and a possible relationship of plasmids to toxin production was examined. The …
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The determination of microbial quality and presence of pathogens and chemical contaminants in aquacultured rainbow trout (Oncorhynchus mykiss) fillets and whole fish from different aquaculture production systems
… pathogens (Listeria monocytogenes, Clostridium botulinum, Salmonella species, Vibrio cholerae, Yersinia enterocolitica and Y. pseudotuberculosis) and general microbial quality of whole aquacultured rainbow trout (Oncorhynchus mykiss) were in compare differing aquacultural systems and growing …
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Sodium hypophosphite inhibition of Clostridium botulinum in pasteurized comminuted pork
… of growth and toxin production of Clostridium botulinum in a model meat system. Fresh comminuted pork was formulated to contain 0, 1000, or 3000 ppm sodium hypophosphite, with or without 50 ppm sodium nitrite, and 156 ppm sodium nitrite. The test formulations were inoculated with an equal …
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The Effects of Modified Atmosphere Packaging on Toxin Production by Clostridium botulinum in Raw Aquacultured Flounder Fillets and Fully Cooked Breaded and Battered Pollock Portions
… Prevention of toxin production by Clostridium botulinum is essential for processors of VAC and MAP refrigerated fishery products. The objective of this study was to determine if C. botulinum toxin development precedes microbiological spoilage and sensory rejection in fully cooked breaded and …
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Validation of high pressure processing (HPP) as a suitable technology for the production of safe tender coconut water
… evaluó el crecimiento potencial de Clostridium botulinum en agua de coco verde y caracterizó múltiples cepas de patógenos vegetativos (Escherichia coli O157:H7, Listeria monocytogenes y Salmonella enterica) en base a su fenotipo de resistencia a las altas presiones. Esto permitió seleccionar …
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Charakterisierung der ADP-Ribosyltransferase CDTa von Clostridium difficile
… die mit den binären Toxinen von C. botulinum (C2-Toxin) und C. perfringens (Iota-Toxin) verwandt ist. Die Transferase besteht aus der Enzymkomponente CDTa (48 kDa) und der Binde- und Transportkomponente CDTb (94 kDa). CDTa ADP-ribosyliert monomeres G-Aktin und führt so zu einer …
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Einfluss der GTPase RhoA auf die axonale Regeneration und die Erholung der Funktion von Neuronen in organotypischen Kulturen
… RhoA, durch das C3-Fusionstoxin aus C. botulinum hat in einer in vivo Studie zur Regeneration von Neuriten geführt. Dieser Effekt sollte in der vorliegenden Arbeit in organotypischen Kokulturen von Cortex und Striatum neonataler Ratten untersucht werden. Neben der neuritenbildenden …
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Clostridium botulinum toxin development in refrigerated reduced oxygen packaged Atlantic croaker (Micropogonias undulatus)
… rate (OTR) on toxin development by Clostridium botulinum in refrigerated raw vacuum packaged croaker fillets, and to determine if toxin development precedes microbiological and/or organoleptic spoilage. Raw croaker fillets were vacuum packaged in oxygen-permeable films (OTR of 10,000 cc/m2/24hr …
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Effect of modified atmosphere packaging on growth of Listeria monocytogenes and nonproteolytic Clostridium botulinum in cooked turkey
… monocytogenes and nonproteolytic Clostridium botulinum type B spores in cooked, uncured turkey was investigated separately under varying conditions of modified atmosphere packaging (MAP), refrigerated and temperature-abuse storage, and lactic acid bacteria (LAB) competition. L. monocytogenes …
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The effect of oxidation-reduction potential on the outgrowth and chemical inhibition of Clostridium botulinum type E spores
… concentration on the outgrowth of Clostridium botulinum type E spores was studied. An airtight flask containing electrodes for continuous measurement of Eh and pH and attached tubing for the exchange and mixing of various gases (i.e. prepurified nitrogen, anaerobic carbon dioxide, hydrogen, …
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A CONTRIBUTION TO THE STUDY OF BIOCONTROL AGENTS APITHERAPY AND OTHER POTENTIAL ALTERNATIVES TO ANTIBIOTICS
… rRNA sequencing technique confirmed that that C. botulinum spores are not likely to be detectable in tested medical grade New Zealand Manuka honey samples. Leptospermum scoparium essential oil showed a marked inhibitory activity against Gram-positive bacteria, including MRSA, M. phlei and B. …