Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"C-type lectin receptor"”.
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Deciphering The C-Type Lectin Receptor Signaling Pathway In Macrophages In Response to Candida Albicans
… in immune-compromised individuals. Dectin-2, a C-type lectin receptor, is required for recognition of <em>C. albicans </em>by innate immune cells and is required for initiation of the anti-fungal immune response. We set out to identify components of the intracellular signaling cascade downstream …
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Maternal β-Glucosylceramides Alter Neonate Hematopoiesis and Lung Microbiota
… are known to signal through a C-type lectin receptor called Mincle. In addition, lung microbial dysbiosis is associated with development of allergic asthma in children. Here we show that maternal β-Glucosylceramides alter hematopoiesis in the neonate by signaling through Mincle in …
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Role of Mincle in Immune Responses to Orientia tsutsugamushi infection
… work defined the contribution of Mincle, a C-type lectin receptor (CLR), in innate immunity to O. tsutsugamushi. Following lethal infection in C57BL/6 mice, pulmonary differential expression analysis revealed Mincle (Clec4e) among the top 5 greatest up-regulated genes, accompanied with CLR …
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Role of Mincle in Immune Responses to Orientia tsutsugamushi infection
… work defined the contribution of Mincle, a C-type lectin receptor (CLR), in innate immunity to O. tsutsugamushi. Following lethal infection in C57BL/6 mice, pulmonary differential expression analysis revealed Mincle (Clec4e) among the top 5 greatest up-regulated genes, accompanied with CLR …
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Synthesis of mannosylated peptides as components for synthetic vaccines
… research was to synthesise ligands for mannose receptors (MRs) that are found on human Antigen Presenting Cells (APCs), for use in synthetic vaccines. Carbohydrate bearing antigens are recognised by MRs which play an important role in binding antigens, migration of dendritic cells (DCs) and …
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Investigating the role of the Dendritic Cell Immunoactivating Receptor in the Immune Response during Pneumocystis murina
… lung disease. Immediate immunity is initiated by receptors that recognize pathogen associated molecular patterns on the surface of pathogenic fungi. Specifically, C-type lectin receptors (CLRs) have been shown to be the principal initiators of innate immune response during fungal infection. …
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Pathogen-Specific Adaptations to Conserved Signaling Pathways in Cryptococcus neoformans
… demonstrate that members of both the Toll-like receptor and C-type lectin receptor families are involved in detecting strains with increased chitin exposure. Finally, in vivo immunological experiments demonstrated that the rim101Δ strain induced a global inflammatory immune response in infected …