Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 36 for “"C-peptide"”.
-
Diabetes mellitus in Adults - Aspects of Incidence, Autoimmunity and C-peptide
… classified by pancreatic autoantibodies and C-peptide. Annual incidences of both type 1 and type 2 diabetes were higher than previously described (27.1/100 000 and 378/100 000). Type 1 incidence was bimodal with peaks in 0-19 and 50-80 years. Patients with latent auto-immune diabetes (LADA) …
-
Development and Application of Reference Measurement Procedures for C-peptide and Insulin in Human Serum
… of Reference Measurement Procedures for C-peptide and insulin in human serum. The context in which these objectives are described is the so-called 'diabetes epidemic' that gradually affects humans worldwide and consequently increases the interest for routine C-peptide and insulin …
-
Associations between Selected Dietary Factors, Selected Obesity-Related Metabolic Markers (Leptin, C-peptide, and High-sensitivity C-reactive Protein), and Lung Cancer: A Matched Case-Control Study Nested in the Prospective PLCO Trial
… frequency, supplemental beta-carotene intake, C-peptide (CP), high-sensitivity C-reactive protein (hsCRP), and leptin concentrations. Data from the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial were analyzed. Linear regression models were used to describe the associations …
-
The combined effects of acute aerobic exercise and omega-3 supplementation on glucose metabolism in healthy, normoglycemic men
… n-3 supplementation on glucose, insulin, and c-peptide concentrations in normoglycemic men. Eleven sedentary, healthy men completed four interventions: rest without n-3 (CON), exercise without n-3 (EX), rest with n-3 (SUP), and exercise with n-3 (EX-SUP). Significant decreases from the CON group …
-
The Acute and Chronic Effects of Palmitic Acid-Rich Triacylglycerols on Cardiovascular Risk
… in plasma lipids, apolipoprotein-B48, glucose, C-peptide, insulin, and glucose dependent insulinotropic polypeptide (GIP) were compared in healthy men (n=25) and women (n=25) following meals providing 50g fat as high-oleic sunflower oil (HOS; control), palm olein (PO), interesterified palm olein …
-
Epidemiology of diabetes in a well defined population in Sweden: the Skaraborg Diabetes Registry
… patients in 1991?2005. Clinical findings, C-peptide protocols, and islet antibodies were compared in their ability to distinguish type 1 from type 2 diabetes, and factors associated with the prognosis of diabetes were explored. The incidence and the age at onset remained stable but the …
-
BEHAVIOURAL ANALYSIS OF ZEBRAFISH RELAXIN-3A MUTANT
The insulin-related neuropeptide relaxin-3 (RLN3) has been implicated in stress responses, feeding and anxiety. Most studies have focused on the peptide encoded by the A- and B-chains, and have been conducted using rodents. This thesis explores the <i>rln3a</i> gene in zebrafish, to test whether …
-
The Effect of Physical Activity on the Insulin Response to Frequent Meals
… the curve (AUC) for serum glucose, insulin, c-peptide, total PYY concentrations, and subjective appetite ratings; as well as insulin pulsatility were determined. Results: No significant differences in baseline glucose, insulin or c-peptide concentrations across study days were observed …
-
Metabolic changes in cellular components of the vasculature : examining the link between diabetes and cancer
… cells following treatment with metal-activated C-peptide were monitored using liquid scintillation, platereader, and microfluidic techniques. As recent reports from the Spence group have identified C-peptide as a stimulator of glucose uptake and adenosine triphosphate (ATP) release from the red …
-
Impact of Physical Activity on Postprandial Lipidemia and Glycemic Control after Chronic Fructose Ingestion
… interleukin-6 (IL-6), glucagon-like peptide 1 (GLP-1), glucose-dependent insulinotropic peptide (GIP), c- peptide, glucose and insulin concentrations. Area under the curve (AUC) and absolute change from peak to baseline concentrations (Δ peak) were calculated to quantify the …
-
Η ΣΥΜΠΕΡΙΦΟΡΑ ΤΗΣ ΓΑΣΤΡΙΝΗΣ ΤΗΣ ΙΝΣΟΥΛΙΝΗΣ ΚΑΙ ΤΟΥ C-ΠΕΠΤΙΔΙΟΥ ΤΟΥ ΟΡΟΥ ΚΑΤΑ ΤΗΔΙΑΡΚΕΙΑ ΤΗΣ ΕΓΚΥΜΟΣΥΝΗΣ ΚΑΙ ΤΗΣ ΛΟΧΕΙΑΣ ΣΕ ΘΗΛΑΖΟΥΣΕΣ ΚΑΙ ΜΗ ΘΗΛΑΖΟΥΣΕΣ ΜΗΤΕΡΕΣ
… LACTATING AND NON LACTATING WOMEN. FOR THE C-PEPTIDE LEVELS, THE SAME PATTERN OF INCREASE AND DECREASE AS IN THE CASE OF INSULIN IS OBSERVED. THE HYPERGASTRINAEMIA SEEN DURING PREGNANCY CAN BE ATTRIBUTED EITHER TO A FEED BACK MECHANISM OR TO GASTRIN PRODUCTION BY THE PLACENTA. THERE IS NO …
-
Potential metabolic effect of sucralose following an oral glucose load in subjects with obesity and normal-weight subjects
… to determine plasma glucose, insulin, C-peptide, glucose-dependent insulinotropic polypeptide (GIP), glucose tracer-to-tracee ratio, and sucralose concentrations. Results: In subjects with obesity, compared to the control condition, sucralose sham-feeding reduced insulin and C-peptide …
-
Influence of dietary treatment on the abdominally obese postmenopausal woman
… blood drawings. Fasting glucose, insulin, c-peptide, fructosamine and a coronary risk profile were obtained. Glucose and insulin responses over two hours to a 35 g load were also measured. Weight loss achieved various outcomes significantly (p L 0. 01) decreasing both waist-to-hip ratio (WHR) …
-
Gestational Diabetes Mellitus- Future risk for mother and child
… later development of type 1 diabetes. Evaluate C-peptide levels in women with GDM as a predictor for future development of diabetes. Aims Paper IV: Investigate the effects of maternal GDM on childhood body mass index (BMI) compared to the age-specific reference values in Sweden and to their …
-
Behavioural and physiological responses of chacma baboons (Papio ursinus) to wildfire in the Cape Peninsula of South Africa
… glucocorticoid concentrations, and urinary C-peptide concentrations three months after the fire to the same three months in the previous year for the same 16 adult females. In the months following the fire, the baboons had a larger spatial range compared to the same months in the year prior. …
-
The acute effects of l-Leucine and l-Isoleucine on glycemic responses in healthy and inactive adults
… facilitate secretion of hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) that are 50-70% responsible for regulating insulin secretion. The purpose of this study was to examine the “priming” effect of pre-ingested L-Isoleucine (ISO) and L-Leucine (LEU) …
-
Evaluation of metabolic and cardiovascular actions of [Pyr1]apelin-13 in patients with Type 2 diabetes mellitus
… complications. Apelin is a naturally occurring peptide investigated in animal models and humans showing beneficial cardiovascular and metabolic properties. Apelin reduces peripheral vascular resistance (PVR) and increases cardiac index (CI) in healthy volunteers and heart failure patients, and …
-
Study of Fat Metabolism and the Interplay with Insulin in Preterm Infants in the First Year of Life
… age and published in Chapter 5. In Chapter 6, C-peptide concentrations-derived from DBS and plasma samples were compared, and the C-peptide concentrations were used to estimate insulin sensitivity indices (HOMA2-IR, HOMA2-IS and HOMA2-%B). Continuous glucose monitoring (CGM) data obtained from …
-
Therapeutic Gene Delivery to Human Pancreatic Islets for Treatment of Diabetes and the Effect of TFO on Liver Fibrosis Induced by Bile Duct Ligation
… levels, and increased serum insulin and c‑peptide levels. Immunohistochemical staining of the islet bearing kidney sections at day 30 after transplantation was positive for human insulin, hVEGF and von Willebrand factor.</p> <p>Further, we decided to replace VEGF with hepatocyte growth …
-
Optimisation of the Investigation of Antibody-Mediated Dysglycaemia
… managed conservatively. Plasma insulin and C-peptide measurements made using mass spectrometry demonstrated under-estimation of insulin and over-estimation of C-peptide concentration using immunoassay in IAS. An observational laboratory and clinical study was also undertaken of 30 …
Page 1 of 2