Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"BzATP"”.
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Einfluß von extrazellulären Nukleotiden auf den eosinophilen Granulozyten
… konnte gezeigt werden, daß ATP, UTP und BzATP konzentrationsabhängig eine Mobilisation von Kalzium in Eosinophilen verursachen. Die Expression des Adhäsionmoleküls CD11b nahm nach Stimulation mit ATP, UTP und BzATP konzentrationsabhängig zu. Darüber hinaus konnte der Nachweis erbracht …
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Roles of the P2X7 receptor in C6 astroglioma: in vitro and in vivo studies
… P2X7Ragonist, 2', 3 '-(benzoy1-4-benzoy1)-ATP (BzATP) induced an increase in intracellularCa2+ concentration, an effect which was largely inhibited by periodate-oxidized ATP(OxATP), an irreversible P2X7R antagonist. BzATP treatment of C6 cells also resulted in ethidium bromide dye uptake …
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New purinergic-based pharmacological targets for the treatment of retinal disorders
… ′)-O-(4-Benzoylbenzoyl)adenosine-5′-triphosphate (BzATP) (a selective P2X7R agonist) in absence or presence of this diterpenoid. I found that HG/BzATP stimulation led to an enhanced barrier permeability and reduced levels of junctional proteins at the membrane cell-cell interface along with reduced …
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Identifizierung regulatorischer Proteindomänen der zytolytischen Eigenschaften des humanen P2X7-Rezeptors
… with agonists like ATP or the more potent BzATP mediates a cytolytic membrane pore. As cell-system we choose COS-7-cells because of the lack of an endogenous P2X7-Receptor. As the cytolytic pore is permeable for cations up to a molecular mass of 900 Da, its possible to detect the cytolytic …
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The physiological role of P2X4 receptors in lysosome function
… lysosome fusion in response to the agonist BzATP. LAMP-GECO was used to measure changes in cytosolic [Ca2+] within the vicinity of the lysosome. Fusion of the Ca2+ reporter (GECO) to the C-terminus of LAMP-1 targets GECO to the cytosolic surface of the lysosome. Co-expression of P2X4R with …