Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"BxPC-3"”.
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Impact du niveau d'activation de la voie Notch/HES1 dans le maintien du phénotype transformé des cellules pancréatiques cancéreuses
… pancréatiques humains : MIAPaCa-2 et BxPC-3 ; celles-ci ont été traitées avec des inhibiteurs de gamma-sécrétase et infectées par des lentivirus codant pour des shARNs ciblant de manière spécifique les ARNm de Notch1 ou Hes1. Nos RÉSULTATS démontrent que les cellules BxPC-3 présentent …
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Molecular mechanisms of bioactive compounds in fruits and vegetables that inhibit pancreatic cancer and their relationship with inflammation
… bioactive compounds on the proliferation of BxPC-3 and PANC-1 pancreatic cancer cells, in vitro, and gene and protein expressions of molecular markers in the GSK-3β/NF-κB signaling pathway. Of the 22 bioactive compounds tested, apigenin and luteolin were the most effective at inhibiting …
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Development and Characterization of Polymeric Nanoparticulate Delivery System for Hydrophillic Drug: Gemcitabine.
… The cytotoxicity in pancreatic cancer cells (BxPC-3) was evaluated by MTT assay. The cellular uptake of gemcitabine solution and gemcitabine loaded alginate nano-particle suspension in BxPC-3 cells was determined for 15, 30 and 60 minutes.|The particle-size and surface-charge was 564.7±56.5nm …
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The development and evaluation of multifunctional silver iron-oxide hybrid nanoparticles towards enhanced pancreatic cancer therapy
… behaviour against pancreatic cancer cell line, BxPC-3, highlighting their potential as an anti-cancer agents within their own right, as well as drug carriers. This work delivered assessments on the multifunctional properties of AgHNPs which could be exploited to synergistically overcome the …
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The development and characterisation of MicroRNA and gemcitabine nanotherapies for the treatment of pancreatic cancer
… miR-143 and miR-145 demonstrated disruption in BxPC-3 functionality while no response was observed with MIA-PaCa2. On the other hand, PANC-1 had variable responsiveness to both miRNAs which highlights the significant role of cellular variation and <br/>molecular signature on the effectiveness of …
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Extraction of Algal Pigments and Their Encapsulation in Lyotropic Liquid Crystalline Nanoparticles for Anticancer Applications
… of in vitro assays upon human pancreatic cancer BxPC-3 cells. Combined with the TS-CUB, the cytotoxicity, photocytotoxicity, cellular uptake, or morphological analysis via the chosen cell line bioimaging have proved promising anticancer effects of the potential drugs derived from marine algae. …
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MUC13 Modulated Nanomechanical and Biophysical Responses in Pancreatic Cancer Cells
… values as compared to moderately differentiated (BxPC-3), well differentiated (HPAF-II) and normal pancreatic epithelia (HPNE). A positive correlation was seen between the adhesion data and aggregation assays - notably, less aggregation was seen in cancer cells as compared to HPNE cells, and
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Synergistic Effects Of Garcinol And Gemcitabine In Enhancing Therapeutic Efficacy In Pancreatic Adenocarcinoma Cells And Its Effect On Microrna Profile
… therapeutic efficacy of garcinol against PaCa (BxPC-3 and Panc-1) cells 2A) its role in dietary interactions with curcumin and 2B) drug sensitization with gemcitabine and 3) identify microRNA targets in PaCa cells on treatment with garcinol and gemcitabine. The activity of transcription factor …