Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"Burn wounds"”.
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Role of human β-defensins in human burn wounds
Background - Burns is a complex condition requiring assessment and addressing of both the wound and the patient in a holistic way. In spite of tremendous improvements in burn care, infection continues to remain an important cause of morbidity and mortality. Human Β Defensins (HBD) are a group of …
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A dressing solution for burn wounds: antibacterial and low-adherent wound dressings
Considering the infection and second trauma caused by dressing changes, development of antibacterial and low-adherent wound dressings is urgently needed. Silver ion is a widely used antimicrobial agent, but its cytotoxicity remains a problem. In this study, low-adherent PAM (polyacrylamide) …
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TESTING THE EFFECT OF A NOVEL HYDROGEN SULFIDE RELEASING PEPTIDE ON INFECTED BURN WOUNDS
Burn wounds are a devastating form of injury that leads to substantial morbidity, mortality, and cost. One of the critical complications of burn wounds is infections, especially with Staphylococcus aureus. Rising antimicrobial resistance is contributing to the complexity of wound management. …
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Computational and Experimental Modeling of the Bioheat Transfer Process of Perfusion in Tissue Applied to Burn Wounds
… problems which is the ability of detecting burn severity. The method was tested with a phantom perfusion system. The results matched known blood perfusion and thermal resistance values. The method was also tested with burns on animal models. Inflammation effects associated with the burns …
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Preserved extracellular matrix in non-enzymatically detached cultured keratinocyte sheets bolsters the healing effects on grafted burn wounds
After escharotomy, full thickness large burn wounds are temporarily covered with cadaver skin because of the limited availability of autologous skin. However, cadaver skin is eventually rejected still requiring autologous skin grafting. To overcome this obstacle, cultured autologous keratinocyte …
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Effects of silver sulfadiazine and actilite honey on bacterial wound colonisation and wound healing in children under twelve years with partial superficial burn wounds at University Adult Teaching Hospital in Lusaka, Zambia
Burn wounds are a global public health concern and Zambia has not been spared. Burn wounds account for 6% of surgical admissions yearly and yet are amongst the common causes of mortality at University Teaching Hospitals (UTH). Burn wounds seen at UTH affect children more than adults and the common …
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Effects of silver sulfadiazine and actilite honey on bacterial wound colonisation and wound healing in children under twelve years with partial superficial burn wounds at University Adult Teaching Hospital in Lusaka, Zambia
Burn wounds are a global public health concern and Zambia has not been spared. Burn wounds account for 6% of surgical admissions yearly and yet are amongst the common causes of mortality at University Teaching Hospitals (UTH). Burn wounds seen at UTH affect children more than adults and the common …
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Effects of light-emitting diode photostimulation on burn wound healing
… in the United States require medical care for burns. Healing of deep burn wounds requires restored perfusion and neoangiogenesis to reestablish blood flow and limit ischemic damage.\r\nWe propose that LED photostimulation, by inducing macrophage proliferation and secretion of pro-angiogenic …
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Practical aspects in first aid cooling of burns
… beneficial effects of first aid cooling of fresh burn wounds have been recognised for many years, particularly with regard to the relief of pain, but there still exists controversy as to the effects of cooling in limiting the damage and the influence on subsequent healing in the burn wound. This …
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An in vitro investigation into the pigmentary phenotype of melanocytes and keratinocyte co-cultures to improve wound healing
On healing, partial-thickness burn wounds usually result in depigmentation of the skin. This is due to the loss of melanocytes. The lack of pigmentation in the healed wound is particularly prominent in dark-skinned individuals and could result in serious psychosocial consequences such as low …
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In situ bioprinting of the skin
Burn injury is a common source of morbidity and mortality in the battlefield, comprising 10 to 30% of all casualties. In the civilian population, there are approximately 500,000 burn injuries requiring treatment each year. Autografts and commercially available skin products are limited in size and …
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Automatic Burns Analysis Using Machine Learning
Burn injuries are a significant global health concern, causing high mortality and morbidity rates. Clinical assessment is the current standard for diagnosing burn injuries, but it suffers from interobserver variability and is not suitable for intermediate burn depths. To address these challenges, …
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Adipose stromal cells enhance keratinocyte survival and migration in vitro, and graft revascularization in mouse wound healing model
In the US, more than 1 million burn injuries are reported annually. About 45,000 injuries due to fires and burns result in hospitalization and ten percent of these result in death every year. Advances in burn treatment have led to a reduction in mortality rate over the last decades. Since more …
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Assessment of Referring Providers Use and Perceptions of the Burnett Burn Assessment and Management Tool for Estimating Burn Size
Accurate assessment of burn percentage and depth are critical aspects in the initial assessment of the burn patient and guide both the immediate clinical management and subsequent need for follow up. To better assist providers in out-lying facilities, The University of Kansas Health System (TUKHS) …
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Investigating the efficacy and mechanism of action of mesenchymal stromal cell therapy in burn wound healing
… and Adipose-MSC (AD-MSC) in the treatment of burn wounds in a large porcine model. Donor matched allogeneic AD-MSC and BM-MSC were applied onto partial thickness burns within a fibrin hydrogel. MSC therapy was similarly efficacious in both groups, increasing wound closure, angiogenesis and …
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Characterization and application of adipose derived stem cells following burn injury
Severe burns induce a prolonged inflammatory response in subcutaneous adipose tissue that modulates signaling in adipose-derived stem cells (ASCs), which hold potential for healing burn wounds or generating skin substitutes. Using a 60% rat scald burn model, we investigated the cellular source of …
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Mast Cell Influence in the Progression of Post-burn Hypertrophic Scar Pathophysiology
… healing in patients with severe full-thickness burns and pose difficult treatment challenges. Despite substantial reduction in postburn mortality, long-term outcomes of HTS are the most serious therapeutic challenge following severe burn injury. Investigations into cellular influences in …
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A MIXED-METHOD FEASIBILITY STUDY COMPARING THE OUTPATIENT ASSESSMENT OF BURN PATIENTS USING A TABLET DEVICE VERSUS THE USUAL FACE-TO-FACE ENCOUNTER
The number of verified burn centers across the U.S. has dramatically decreased, negatively impacting access to burn care. Telehealth is a solution for burn care, however there is minimal research evaluating burn care through telehealth. The primary purpose of this mixed method feasibility study was …
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The Development and Evaluation of a Range of Phototherapeutic Dyes Towards Infection Control
… with a light source. Patients who suffer burn wounds are at a higher risk of acquiring an antimicrobial infection due to the immunosuppressive nature of the burn wound site, making infections one of the main causes of deaths in burn patients. The potential use of photodynamic therapy as a …
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Self-assembled Peptide Hydrogels for Therapeutic H2S Delivery
… aureus (Xen29), a commonly found bacterium on burn wounds, showed significant antimicrobial effects. APAs S-FE and C-FE eliminated Xen29 and inhibited the biofilm formation, while S-FE always showed better effects than C-FE. These antimicrobial H2S-releasing APA hydrogels provide a new approach …
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