Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Bunyavirus"”.
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INNATE IMMUNITY IN ENCEPHALITIC BUNYAVIRUS INFECTION: OVERCOMING NEURONAL VULNERABILITY
Several arthropod-borne bunyaviruses cause encephalitic disease in humans, primarily infecting neurons in the brain. Two of the most prominent examples are Rift valley fever virus (RVFV), and La Crosse virus (LACV). These viruses may preferentially infect neurons due to dampened neuronal innate …
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Investigation of mosquito (diptera: culicidae)-borne viruses circulating in some selected areas of Lusaka district, Zambia.
… showed an 85.69% and 97.45% identity with Culex bunyavirus 2 for nucleotide (blastn) and protein (blastp) respectively. The detected virus showed the virus is closely related and clusters with Culex bunyavirus 2 and Culex bunya-like virus which are unclassified bunyaviruses forming a separate …
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Investigation of mosquito (diptera: culicidae)-borne viruses circulating in some selected areas of Lusaka district, Zambia.
… showed an 85.69% and 97.45% identity with Culex bunyavirus 2 for nucleotide (blastn) and protein (blastp) respectively. The detected virus showed the virus is closely related and clusters with Culex bunyavirus 2 and Culex bunya-like virus which are unclassified bunyaviruses forming a separate …
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Vaccine Development Strategies for Crimean-Congo Hemorrhagic Fever Virus and its Tick Vector
… hemorrhagic fever virus (CCHFV) is a tick-borne bunyavirus with an extensive geographic range and complex ecology. Ticks within the Hyalomma genera are the primary vector and reservoir of the virus and maintain the virus through a cryptic tick-vertebrate-tick cycle in nature. However, infection …
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Forest disturbance, mosquito vector ecology and La Crosse virus dynamics in southwestern Virginia
… of an emerging focus of this interior forest bunyavirus. I investigated how the temperate forest mosquito community, LACV vectors, and the LACV amplifying vertebrate host (chipmunks) were impacted by logging. This research was conducted across an experimental FCD gradient (from least to most …
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HIJACKING OF CELLULAR PATHWAYS BY NOVEL TICK-BORNE PHLEBOVIRUS
Severe Fever with Thrombocytopenia Syndrome (SFTS) virus is an emerging tick-borne Phlebovirus isolated from patients presenting with hemorrhagic manifestations. Case fatality rates of 12-50% have been reported. Limited information regarding SFTS virus pathogenesis is known. Inhibition of …
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Reverse genetics system and fucntion of NSM protein of Rift Valley fever virus (family Bunyaviridae, genus phlebovirus)
Rift Valley fever virus (RVFV) (genus Phlebovirus, family Bunyaviridae) has a tripartite negative-strand genome, causes a mosquito-borne disease that is endemic in sub-Saharan African countries and results in large epidemics among humans and livestock. Furthermore, it has potential as a …
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Characterization of Innate Immune Mechanisms Against RVFV and a Potential Target for Antivirals
Rift Valley fever virus (RVFV) is a mosquito-borne zoonotic pathogen, which affects both humans and livestock. RVFV belongs to the Bunyaviridae family, genus Phlebovirus and consists of a tripartite genome (L-, M- and S- segments). NSs, encoded in the S- segment promotes degradation of PKR and …
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The study of ancient viral class II envelope fusion proteins within the viral retroelements of Nematoda and the nuclear plasmids of Dictyostelium
Within the parasitic nematode Ancylostoma ceylanicum, a nearly 20 million-year-old Bel/Pao LTR-retrotransposon encodes an ancient viral class II envelope fusion protein. Typically, retroviruses and related degenerate retrotransposons encode a hemagglutinin-like class I envelope fusion protein. A …