Global ETD Search
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Showing 1 to 2 of 2 for “"Btg2, B-Cell translocation gene 2"”.
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Regulation of Senescence Phenotypes by TIS21 gene in Huh7 Human Liver Cancer Cells
일반적으로 Cellular senescence란 시간이 지나면 자연적으로 세포 증식이 억제되고 세포내 항상성 유지가 어렵게 되는 것을 말한다. 이러한 cellular senescence는 tumour cell에서도 일어나는데 tumour cell에서의 senescence는 그 결과가 tumour-suppression 으로서도 작용하지만 tumour-promotion 으로서도 작용되어질 수 있다고 알려져 있다. 본 연구에서 사용한 유전자인 TIS21은 TPA에 의해 유도되어지는 21번째 sequences로서 …
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Role of BTG2/TIS21/PC3 in differentiation of myeloid leukemia cells and its regulation under stress conditions
… inducible sequence 21), an ortholog of human BTG2 (B-cell translocation gene 2) and rat PC3, is a tumor suppressor that belongs to antiproliferative gene family, and is implicated in a variety of biological processes. Deregulation of c-Myc transcription factor is common in leukemia and …