Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 99 for “"Brucella"”.
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Regulatory Control of Brucella Genetic Transcription
Brucella abortus is a causative agent of brucellosis, a chronic bacterial disease with global distribution. The pathogenesis of Brucella remains poorly understood, despite a century of study. During infection, the Brucella bacterium endures numerous environmental and host stresses but establishes a …
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Presumptive identification of smooth Brucella strain antibodies in canines
… by a Gram-negative coccobacillus. There are four Brucella strains of zoonotic importance in our domestic species, subdivided by their culture phenotypes: Brucella abortus (B. abortus, B. melitensis, B. suis (smooth strains) and B. canis (rough strain). Dogs can serve as hosts for all four of the …
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Assessment of the Expression of Brucella Abortus Heat Shock Protein, Groel, in Vaccinia Virus to Induce Protection Against a Brucella Challenge in Balb/C Mice
… by the rate of splenic clearance of live Brucella. In spite of demonstrating specific GroEL antibodies in recombinant vaccinia injected mice, no significant level of protection was demonstrable. Preliminary lymphocyte transformation assays were carried out to establish if a cell mediated …
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Investigating the immune response to central nervous system invasion by Brucella
… the first researchers to successfully visualize Brucella in the brains of experimentally-infected mice and suggested a potential method of entry within phagocytes. Additionally, adoptive transfers from both wild-type and IFN-g-deficient mice revealed that T cell mediated immunity is sufficient in …
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Characterization of the VtlR regulons in Brucella abortus and Agrobacterium tumefaciens
Brucella abortus and Agrobacterium tumefaciens are pathogenic bacteria that infect animals and plants, respectively. These bacteria are genetically similar and are found within the same Class, Alphaproteobacteria, and Order, Rhizobiales, of the domain Eubacteria; however, they survive and replicate …
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Ochrobactrum anthropi: a soil bacterium for the study of Brucella virulence
The species of Brucella were isolated and characterized almost 120 years ago and their genomes sequenced for almost 4 years. Compared to other bacterial pathogens relatively, little is known about the factors contributing to their persistence in hosts and multiplication within phagocytic cells. …
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Role of entF Gene in Iron Acquisition by Brucella abortus 2308
Brucella causes undulant fever in humans and uterine and systemic infection leading to abortions in domestic animals and wild life. For the acquisition of iron in mammalian hosts, species of Brucella are known to produce two siderophores, 2, 3-dihydroxy benzoic acid (2, 3-DHBA) and brucebactin. …
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Expression of Bacillus Anthracis Protective Antigen in Vaccine Strain Brucella Abortus Rb51
… against the respiratory form of the disease. Brucella abortus is a facultative intracellular bacterium that causes chronic infection in animals and humans. As with other intracellular pathogens, cell mediated immune responses (CMI) are crucial in affording protection against brucellosis. B. …
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Mathematical models of immune responses following vaccination with application to Brucella infection
… Today the two most commonly used vaccines are Brucella abortus vaccine strain 19 and strain RB51. Both vaccines have been shown to be effective, but the mechanisms of immune responses following vaccination with either of the vaccines are not understood yet. In this thesis we analyze the …
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Brucella abortus RB51 vaccine: Testing its Spectrum of Protective and Curative Characteristics
Brucella abortus (BA) are gram-negative, facultative intracellular bacteria that cause abortions in cattle and debilitating illness in humans. The US is now virtually free of bovine brucellosis, but the disease is endemic in wildlife. The official brucellosis vaccine in the US is strain RB51 …
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To determine the incidence of brucella abortus and certain other organisms in tonsils
The primary object of the investigation recorded in this thesis was to determine, if possible, the frequency in which the Bacillus abortus of Bang could be recovered from tonsil tissue. It is obvious that normal tonsils would not be available for this study and, therefore, one was compelled to use …
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Genetic and Immunological Analyses of a Brucella abortus Protein Exhibiting Lectin-like Properties
Brucella abortus is a facultative, intracellular zoonotic pathogen, which can cause undulant fever in humans and abortion in cattle. Despite all of the progress in brucellosis research, there are still many unanswered questions regarding the molecular mechanisms involved in the pathogenesis of …
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Evaluation of the Aging Immune System Using a Mouse Model of Brucella Infection
… effect of aging on the immune response against Brucella. To elucidate the mechanism of immune dysregulation in old, old and young DBA/2 and BALB/c mice were infected with wild-type B. abortus strain 2308. The old and young mice were also vaccinated with vaccine B. abortus strain RB51 …
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Characterization of Deoxycholate-Responsive Genes Utilized by Brucella abortus 2308 During Oral Infection
… recurring disease caused by the bacterium Brucella abortus, along with other species of the genus Brucella, and is one of the most common bacterial zoonosis worldwide. The bacteria preferentially infect and reside within host macrophages, causing an undulant fever, joint pain, and other …
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Unraveling the host innate immune response to a respiratory model of Brucella abortus
Brucella are Gram-negative intracellular bacteria that cause abortion and infertility in livestock and chronic disease in humans. The Centers for Disease Control and Prevention (CDC) categorizes them as class B pathogens due to their zoonotic potential. Currently, there are no efficacious Brucella …
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Relative merits of standard versus modified procedures for isolation of Brucella abortus from milk
Call number: LD2668 .T4 1952 W4
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Relative merits of standard versus modified procedures for isolation of Brucella abortus from milk
Call number: LD2668 .T4 1952 W4
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