Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"Bronchopulmonary dysplasia"”.
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Ceramides as Therapeutic Targets in Bronchopulmonary Dysplasia
Bronchopulmonary dysplasia (BPD) is a chronic lung disorder associated with extremely premature birth, resulting from arrested development of the microvasculature and consequently disrupted alveologenesis. Premature infants are dependent on respiratory support, including oxygen supplementation and …
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Association Between New Bronchopulmonary Dysplasia and Pulmonary Hypertension in Extremely Premature Newborns
Bronchopulmonary dysplasia (BPD) is one of the most significant chronic complications of premature newborns treated in neonatal intensive care units. This thesis provides a deep review of the pathogenesis of BPD, the association of hypoxia with the development of BPD associated pulmonary …
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The Efficacy and Safety of Montelukast Sodium in the Prevention of Bronchopulmonary Dysplasia
… of Montelukast sodium in the prevention of bronchopulmonarydysplasia(BPD) METHODS: This study was designed as a multicenter, prospective, randomized, open labelled, parallel-group, intervention study. 66 infants were enrolled and allocated to Case group (n=30) and Control group (n=36) by …
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Vulnerable infants: Prediction and diagnosis of respiratory outcomes
… with respiratory system disorders: (i) Bronchopulmonary Dysplasia, the most common adverse outcome in premature infants, (ii) Childhood Asthma, the most common chronic condition among children, and (iii) Sudden Infant Death Syndrome, the third leading cause of death among all infants in …
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Extracellular Vesicles to Evaluate the Effects of Mesenchymal Stromal Cells in the Premature Lung
Bronchopulmonary dysplasia (BPD), caused by disrupted lung development, is a common complication of prematurity without effective treatment. Mesenchymal stromal cells (MSCs) improve features of experimental BPD, such as lung function, structure, and inflammation. The HULC-1 trial assessed the …
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Morbidity and Mortality in small for gestational age very low birth weight infants in a middle-income country
… 2.1, 95% confidence interval (CI) 1.6-2.7), bronchopulmonary dysplasia (14% vs 4.5%, aRR 3.7, 95% CI 2.3-6.1) and late onset sepsis (16.7% vs 9.6%, aRR 2.3, 95% CI 1.6-3.3) were higher in the small for gestational age than in the non-small for gestational age group. Conclusion: Small for …
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Trasmissione post-natale del citomegalovirus attraverso il latte materno al neonato VLBW
… infants [GE<28 ws]; P<.05). Furthermore, bronchopulmonary dysplasia (defined both as oxygen-dependency at 30 days of life and 36 ws of postmenstrual age) correlated with symptomatic infection (3/3 symptomatic vs 0/6 asymptomatic: P<.05). Conclusion Our data suggest that CMV infection …
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The Role of Semaphorin-Neuropilin-1 Signalling in Pulmonary Vascular Development
… of infancy, including alveolar capillary dysplasia (ACD) and bronchopulmonary dysplasia (BPD). To understand the etiology of – and advance treatments for – such diseases, we must first identify the fundamental genetic regulators that orchestrate normal parenchymal development. Neuropilin-1 …
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A Comparative Effectiveness Study of Continuous Positive Airway Pressure (CPAP) Related Skin Breakdown when using Different Nasal Interfaces in the Extremely Low Birth Weight (ELBW) Neonate
… in the neonatal population by reducing bronchopulmonary dysplasia (BPD). The neonate is vulnerable to injury secondary to immature physiological systems and skin structures and the current CPAP devices place constant pressure on nares, nasal septum and forehead, increasing injury risk. …
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Understanding Intercellular Signaling During Lung Injury-Repair
… applied our interactome to a hyperoxia model for bronchopulmonary dysplasia, another injury model affecting a majority of lung cell types. In concert with our sequencing approaches to study cellular interactions, we surveyed Sendai virus-infected lung tissue to understand the path by which airway …
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Surfactant for the treatment of respiratory distress syndrome in very low birth weight infants at a level 2 hospital: a descriptive retrospective cohort study – safety and efficacy
… mortality rate was 17(25.8%). The incidence of Bronchopulmonary dysplasia was 4(6%).The incidence of pulmonary air leak was 2(3%) and pulmonary haemorrhage was 6(9.1%). The median number of days on mechanical ventilation for the patients who were ventilated was 3 days (IQR 2-6). The median total …
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Umbilical artery Doppler velocimetry in predicting the perinatal outcomes in small for gestational age infants
… > grade 2), necrotizing enterocolitis (NEC), bronchopulmonary dysplasia (BPD), respiratory distress syndrome (RDS) and perinatal death. The logistic regression showed UASD a statistically significant risk factor in predicting the adverse neonatal outcomes (Odds ratio 2.4; 95% CI 1.2-5.6). …
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Regulation of Lung Mesenchymal Cells By Epithelial Wnt Ligands
… for alveolus formation and is reduced in bronchopulmonary dysplasia (BPD), a chronic lung disease often associated with premature birth. Mutants also showed increased smooth muscle actin (ACTA2) expression in pericytes in the adult murine lung, a phenotype reminiscent to pulmonary …
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THE USE OF ENTERAL STERILE WATER FOR THE TREATMENTOF HYPERNATREMIAIN EXTREMELY LOW BIRTH WEIGHT INFANTS
… comorbidities such as patent ductus arteriosus, bronchopulmonary dysplasia and intraventricular hemorrhage. The purpose of this prospective, randomized control trial (N=19) was to examine the use of enteral sterile water feeds as an alternative management strategy on the incidence and duration of …
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Sudden unexpected death in infants: a forensic genetic investigation in a South African cohort
… immune-compromised and the second may have had bronchopulmonary dysplasia. The findings in this study highlight possible new candidate variants to assess in SUDI cases, and has directly contributed to the development of a molecular autopsy which is locally relevant. It is evident that until …
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Studies on polyunsaturated fatty acid content and lipid peroxidation in preterm infant nutrition from non-maternal sources.
… to the development of necrotising enterocolitis, bronchopulmonary dysplasia or retinopathy of prematurity. Human milk banking practices that might alter LCPUFA and LPP content of DHM were identified through a nationwide survey of human milk banks; and recommendations for human milk banking, to …
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Enteral docosahexaenoic acid supplementation to attenuate inflammation in the preterm infant
… efficacy of an enteral DHA emulsion to reduce bronchopulmonary dysplasia (BPD) in preterm infants < 29 weeks gestation compared to a standard soy emulsion without DHA. Prior to analysis of biological samples from preterm infants, the immune response to enteral DHA and soy emulsions in human …
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The impact of malnutrition in premature infants on hospital length of stay: a retrospective study in a metropolitan neonatal intensive care unit
… complications with the highest LOS included bronchopulmonary dysplasia (BPD) at 90.6±19.6 days LOS, necrotizing enterocolitis (NEC) with 88 days LOS and congenital heart disease (CHD) with 85.8±33.4 days LOS. Statistically comparing the LOS of infants with BPD and malnutrition to all subjects …
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Valores normales y relación con la displasia broncopulmonar del grosor de línea pleural y el sistema de puntuación ecográfica en recién nacidos
… mm. LUNG ULTRASOUND SCORE AS EARLY PREDICTOR OF BRONCHOPULMONARY DYSPLASIA IN VERY LOW BIRTHWEIGHT INFANTS Introducción: La EP se utiliza actualmente cada vez más para el diagnóstico y la monitorización de enfermedades respiratorias en recién nacidos, pero no está apenas desarrollada en las …