Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 23 for “"Bronchiolitis"”.
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A Bronchiolitis Study: The Overuse of Bronchiolitis Therapies in Children Admitted into the Hospital
<p>Bronchiolitis is prevalent among infants of 0 to 12 months, and usually caused by a variation of viruses. Signs and symptoms consist of coughing, rapid breathing, and an occasional fever in some infants. Bronchiolitis is not treated with antibiotics, but rather with proper medical examination …
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Improving the care of infants with bronchiolitis : Using knowledge translation to close the evidence-practice gap
Aim: Bronchiolitis is the most common reason infants are hospitalised in the developed world. International clinical guidelines recommend supportive care (respiratory and hydration), and do not recommend use of salbutamol, antibiotics, glucocorticoids, adrenaline or ordering chest radiographs. …
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EPIDEMIOLOGICAL AND FUNCTIONAL APPROACHES TO EVALUATE THE EFFECTS OF PARTICULATE MATTER EXPOSURE IN INFANTS WITH VIRAL BRONCHIOLITIS
… subgroups, such as infants and chil\dren. Acute bronchiolitis, a common clinical condition characterized by inflammation and obstruction of bronchioles, is generally caused by a viral infection of the lower airways and is estimated to be the leading cause of hospitalization of infants worldwide. …
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The Clinical Spectrum, Aetiology and Disease Progression of Children with Post-infectious Bronchiolitis Obliterans at Tertiary Paediatric Pulmonology Service in Cape Town, South Africa
… in the paediatric age group. Post-infectious bronchiolitis obliterans (PIBO) is a cause of obstructive airway disease children, with limited data in African children. Aim: To describe the clinical spectrum, aetiology, and disease progression of children with post-infectious bronchiolitis …
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A guinea pig model of human respiratory syncytial virus lung infection
… of acute respiratory syncytial virus (RSV) bronchiolitis are at increased risk for developing asthma, a disorder characterized by reversible airway obstruction, airway hyperresponsiveness and airway inflammation. Because latent or persistent pulmonary viral infections have been implicated in …
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Tissue repair in lung disorders
… pulmonary disease, asthma, obliterative bronchiolitis, and after lung transplantation is not well understood. One of the key players in fibrosis is the fibroblast and its progenitor, the fibrocyte. The fibroblast is the main producer of extracellular matrix molecules such as collagen, …
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ΕΠΙΔΡΑΣΗ ΤΗΣ ΑΝΑΠΝΕΥΣΤΙΚΗΣ ΔΥΣΧΕΡΕΙΑΣ ΣΤΟ ΜΕΤΑΒΟΛΙΣΜΟ ΤΟΥ ΦΩΣΦΟΡΟΥ ΣΕ ΝΕΟΓΝΑ ΚΑΙ ΒΡΕΦΗ
… 26 NEONATES WITH R.D AND 16 INFANTS WITH BRONCHIOLITIS. THREE BLOOD SAMPLES WERE TAKEN FROM EACH NEONATE AND INFANT. THE RESULTS SHOW THAT THE NEONATES WITH R.D HAD LOWER RI LEVELS BOTH INTRA AND EXTRACELLULAR THE FIRST SAMPLE, THAT CONTINUED TO DECREASE DURING STUDY. THE MEAN VALUES …
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Tuberculosis-associated obstructive pulmonary disease: a clinical, radiological and pathophysiological study of the contribution of previous pulmonary tuberculosis in a community-based study of chronic obstructive pulmonary disease
… but likely includes: airway narrowing (from bronchiolitis, bronchiectasis or persistent low-grade inflammation associated with healed PTB); and reduced lung elastic recoil from coexistent emphysema. The present study investigated the structure and function of the lung in subjects with …
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Traffic pollution and chronic respiratory disease. Epidemiological studies in children and adults in southern Sweden.
… diagnosis, obstructive bronchitis diagnosis or bronchiolitis diagnosis, in children 0-6 years. In conclusion, living close to dense traffic was associated with prevalence of asthma, COPD, allergic rhinitis and eczema, in adults, but not with incidence of asthma or other obstructive respiratory …
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Modulation of immune responses by human paraininfluenza virus
… is a key respiratory pathogen responsible for bronchiolitis, pneumonia and croup. The persistent nature of this virus and its ability to reinfect within a short space of time has led to successive failures in the design of a vaccine against this virus. To understand the lack of protective …
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The impact of chest radiography on the diagnosis, clinical management and outcome of acute lower respiratory infections in children
… radiograph group (14.4% vs. 8.8%, p=0.03) and bronchiolitis less often ( 44% vs. 56%, p=0.005). Antibiotic usage was higher in the radiograph group (60.8% vs. 52.2%, p=0,05). There were no differences in subsequent health facility usage. Interpretation. Despite a net change in diagnosis and an …
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Interferon-Dependent Mechanisms of Disease Pathogenesis in Respiratory Syncytial Virus Infection
… contributing factors, the pathogenesis of RSV bronchiolitis and the cellular/molecular mechanisms that determine its clinical severity remain incompletely understood. A hallmark of RSV is its resistance to the canonical antiviral activity of interferon type I (IFN I) and at the same time its …
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Evaluation of an Early Discharge Policy For Infants With Apnea of Prematurity
… costs were approximately $58,000 in both groups. Bronchiolitis was the leading cause for hospital readmission and there was no difference in the rate of hospital readmissions. Based on interviews with NICU clinicians, the policy works well and early discharge is advantageous to the infant and …
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Identification and Analysis of Omentum Derived Suppressor Cells in Regards to Th17 Inhibition
… <p>Th17 is associated with the development of bronchiolitis obliterans following lung transplantation, a syndrome involving chronic inflammation of airways and development of mucus plugs. We tested the role of omental cells as cellular therapy in our lung transplant model, under the hypothesis …
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A Novel Correction for the Adjusted Box-Pierce Test — New Risk Factors for Emergency Department Return Visits within 72 hours for Children with Respiratory Conditions — General Pediatric Model for Understanding and Predicting Prolonged Length of Stay
… New respiratory conditions including acute bronchiolitis, pneumonia, and asthma were identified as risk factors for return visits to ED.</p> <p>Thirdly, I ambitioned to design and implement a comprehensive study to identify new clinical and demographic factors associated with prolonged …
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Antikörper-Entwicklung nach Respiratory Syncytial Virus (RSV)-Infektion bei Frühgeborenen und Säuglingen
… 2-Kinder gleichermaßen die typische Bronchitis/Bronchiolitis- bzw. Pneumoniesymptomatik auf. Bei der Untersuchung des AK-Status hatten die RSV-negativen Kinder häufiger und deutlich ausgeprägtere IgG-AK. Nach erfolgter RSV-Infektion zeigt sich eine Erweiterung des AK-Spektrums und ein …
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Do respiratory epithelial cells ‘remember’ early life microbial exposure through epigenetic changes?
… linked severe respiratory syncytial virus (RSV) bronchiolitis in infancy with a higher risk of developing recurrent wheeze or childhood asthma, yet the pathomechanism behind this phenomenon remains undetermined. Here I hypothesise that RSV infection can epigenetically imprint airway epithelial …
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A review of the use of high flow nasal cannula oxygen therapy in hospitalized children at a regional hospital in the Cape Town Metro, South Africa
… The most common diagnoses were pneumonia, bronchiolitis, and asthma. Asthma, anaemia, and cardiac abnormalities were the most prevalent underlying co-morbidities. Two children died in each group. All 54 children in the pre-HFNC group were transferred to L3; 38 (70.4%) needed CPAP or …
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A survey of knowledge in the case management of acute respiratory infections (ARI) in children under the age of 5 years, amongst doctors and clinical nurse practitioners (CNPS) in the Khayelitsha district of Western Cape Province
… with respect to questions on tuberculosis, bronchiolitis and croup. A comparative analysis was carried out on the knowledge scores of the doctors in the public sector, the private General Practitioners (GPs) and the CNPs. Correlation between years of experience and scores were measured. A …
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Role of Dendritic Cells in Pathology of Respiratory Syncytial Virus Infection in Neonates
… virus (RSV) is one of the leading causes of bronchiolitis in children. We have shown that neonatal mice respond to primary RSV infection with T helper type 2 (Th2) biased immune responses, which are enhanced following reinfection. Dendritic cells (DCs) including myeloid DCs (mDCs) and …
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