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Showing 1 to 1 of 1 for “"Broad Spectrum Cancer Targeting"”.

  1. Nucleic Acid Scaffold-dependent Proximity-mediated Enzyme Response (NASPER) - A Proof of Concept Study

    Chatterjee, NileshUniversity of Cambridge2022

    … hTERT RNA is overexpressed in around 90% of all cancers but targeting it has been unsuccessful to date due to the inability of this approach to kill telomerase-expressing cells leading to the evolution of telomerase-independent cells. The approach proposed in the thesis (NASPER), aims to target …

    cambridge Repository record