Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Bregs"”.
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Engineering B Cells For Use In Immunotherapy and Cancer
… specific to pathogens, regulatory B cells (Bregs) have recently been shown to control inflammatory responses in multiple diseases through the production of anti-inflammatory cytokines, including interleukin (IL)-10, IL-35 and transforming growth factor-beta (TGF-b). Ex vivo expansion of B …
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Biological effects of synthetic biomolecules that may either mimic or antagonise the function of hCG in the development of cancer and autoimmune disease
… T cells (Tregs), and regulatory B cells (Bregs). Interestingly, hCG is also secreted by certain tumours, helping them evade immune detection by creating a tolerogenic environment. This project aimed to design and synthesize small oligopeptide aptamers that specifically bind to the Beta and …
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Gut Microbiota Regulation of SLE Pathogenesis
… in mice. Transcriptome-based changes in Bregs during active disease were confirmed through phenotypic analysis. These findings provided crucial insights into the dynamic role of B cells in the pathogenesis of SLE. In addition, we delved into the intricate connection between SLE and the …
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The role of B cells in the amplification and in the regulation of transplant rejection.
… a<br/>variety of mechanisms. Regulatory B cells (Bregs) have recently discovered and<br/>their role in regulating autoimmune diseases has been demonstrated in different<br/>murine models. In the context of transplantation B cells are generally thought to<br/>promote graft rejection through the …