Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 108 for “"Brain structure"”.
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Brain Structure in Older Adult Siblings
<p>Considerable variability exists in patterns of brain aging within and across individuals. Quantifying familial contributions to brain structure in late life may help us understand this variability. We estimated heritability of gray and white matter volumes and cortical thickness in a sample of …
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Lifestyle, Brain Structure and Cognitive Ageing
This thesis explores the lifestyle and brain structure correlates of cognitive ageing. Using large datasets and a range of multivariate statistical approaches, it is divided into three empirical sections, which are framed by a General Introduction and Conclusion. The first Chapter, the General …
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Socioeconomic Disadvantage and Brain Structure in Adulthood
… this association is through variations in brain development. While associations between concurrent socioeconomic disadvantage and brain structural development have been established, it is unclear if there are prospective associations between childhood disadvantage and brain structure later …
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Brain Structure and Age of Acquisition in Bilinguals and Monolinguals
… acquisition (AoA) plays any role in determining brain structure. Whereas some studies suggest that bilinguals handle both languages via a single set of cognitive control regions regardless of AoA, others suggest that each language depends on different sets of brain regions for late (but not …
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The impact of maternal HIV infection on uninfected neonate brain structure
… therapy (ART) exposure on the developing brain is not well understood. While HEU children perform better than their counterparts living with HIV, they continue to demonstrate greater neurodevelopmental delay than HIV-unexposed uninfected (HUU) children. As a result, neuroimaging studies …
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Brain structure and function associated with emotion-cognition interactions: A multi-method investigation
… emotional challenges are scarce. At the level of brain structure, there has not been clear consensus on what the most appropriate tools and techniques are for investigating individual differences. At the level of brain function, the link between spatial (where) and temporal (when) aspects of the …
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BRAIN STRUCTURE AND FUNCTION ASSOCIATED WITH EMOTION DYSREGULATION IN TYPICAL DEVELOPMENT AND NEURODEVELOPMENTAL DISORDERS
Subcortical and cortical brain regions mature at different rates, which vary across individuals, contributing to problems like emotion dysregulation (ED). However, the neurobiology underlying ED in the typically developing children and adolescents (TD) and the clinical populations such as …
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Regional Differences in Brain Structure Underlying Childhood Stuttering Persistence and Recovery: An MRI Study
… of cortical, subcortical, and cerebellar structures that normally work together in a coordinated fashion to achieve timely and efficient sensorimotor processing. Stuttering recovery, on the other hand, appears to involve maturation of these structures to resemble tissue growth in normally …
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Theory-based Explorations of Associations between Human Brain Structure and Intelligence from Childhood to Early Adulthood
… progress in this pursuit by exploring how human brain structure and intelligence correlate and co-develop with each other from childhood to early adulthood (ages 5 – 22 years). This endeavour is undertaken in three large cohorts (N range: 337 – 2072), guided by theory (e.g., crystallised and …
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Neuro-zika: Brain structure and functional organization of adult humans with zika virus infection and severe neurological complications
… confined to a few single cases of structural brain changes. Further, no functional neuroimaging studies have been carried out to investigate how ZIKV affects adult human brain function. In this first case-control neuroimaging study, we investigated nine rare adult patients with ZIKV-related …
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The influence of low physical activity levels versus extreme physical activity levels on brain structure and working memory
… impact of extreme physical activity levels on brain matter volume and working memory is not well understood. This thesis thus investigated the relationship between different levels of MVPA, brain structure, and working memory. The aim of the thesis was to understand the relationship between …
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Type 1 diabetes mellitus and the brain: influence of clinical complications and genetic factors on brain structure and cognitive function
… and repeated exposure may be detrimental to the brain. Microvascular disease, manifest as retinopathy, neuropathy or nephropathy, frequently complicates diabetes, the risk being related to long-term glucose control and increasing disease duration. Microvascular disease may also affect the …
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Effects of HIV and different anti-retroviral therapy (ART) regimes on brain structure in HIV infected children at age 7
… the outcome of HIV and early ART on children's brain structure and neurocognitive skills. This study therefore investigated the effects of HIV and early ART on brain morphometry in 7-year old children using magnetic resonance imaging (MRI). Participants were 99 Xhosa children (56 HIV-infected …
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Elucidating the Impact of Previous Head Injury on Cognition, Brain Structure, and Pathophysiology in Cognitively Normal Individuals Across the Adult Lifespan
Mild traumatic brain injury (mTBI), or concussion, is a common experience and awareness of mTBI has been increasing. There has been growing concern regarding potential long-term effects of concussion on cognition and risk for neurodegenerative disorders. This concern is heightened for athletic …
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Structural brain connectivity of HIV-positive children: a graph network analysis study
… Prior imaging studies have shown abnormal brain structure in adults and children infected by HIV. Graph theory analyses have been applied to HIV neuropathogenesis previously, these have demonstrated significant disruptions to brain connectivity in older HIV+ adults on treatment. However, no …
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Experience-Dependent Plasticity in the Mushroom Bodies of the Honey Bee Brain
I am interested in the mechanisms that modify brain structure in response to experience. The model organism under study is Apis mellifera, the European honey bee. The honey bee has a rich behavioral repertoire that can easily be studied both in the laboratory and under natural conditions. The goal …
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Statistical Methods for Extracting and Comparing Patterns in Multimodal Neuroimaging Studies
… a vital part of advancing our understanding of brain health and the etiology of neuropsychiatric disorders. But the inherent complexity and dimensionality of these data necessitate new statistical methods to produce replicable and interpretable results. In this work, we contribute to a growing …
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A role for nutrition in healthy brain aging
… understand nutrition’s impact on cognition and brain health across the life span. While accumulating evidence indicates healthy cognitive aging is dependent upon both brain health and nutritional status, the relationship between nutrition, cognition, and brain structure and function remains to …
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