Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 1 of 1 for “"Brain pharmacokinetics"”.
-
Mechanistic modeling of alpha-synuclein aggregation and brain pharmacokinetics for drug development in neurodegeneration
… in evaluating a priori predictions of brain drug distribution against experimental homogenate measurements. Building on the Rodgers & Rowland method and related tissue composition-based models, we propose a homogenate-specific metric that accounts for artifacts induced by tissue …