Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"Brain model"”.
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The Development and Validation of a Neural Model of Affective States
… the non-invasive measurement and prediction of brain states in real-time, which can be used to provide feedback to facilitate regulation of brain states (LaConte, 2011). Real-time functional magnetic resonance imaging (rt-fMRI)-guided neurofeedback, has promise as a novel therapeutic method in …
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Development of Methodologies for the Solution of the Forward Problem in Magnetic-Field Tomography (MFT) Based on Magnetoencephalography (MEG)
… of algorithms and methods for realistic brain model, development of realistic neuronal source, computational approaches, and validation techniques. Every delivered methodology is tested and analyzed in terms of mathematical and computational errors. Optimizations required for error …
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An Anatomically Representative Atlas-Based Finite Element Model of the Human Brain for Studying Brian Injury Biomechanics: Development, Validation and Comparison to Existing Models
Traumatic brain injury (TBI) is a leading cause of disability and injury-related death. To enhance our ability to prevent such injuries, we can study brain response using validated finite element (FE) models. In the current study, a high-resolution, anatomically accurate FE model was developed from …
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A new class of neural architectures to model episodic memory : computational studies of distal reward learning
A computational cognitive neuroscience model is proposed, which models episodic memory based on the mammalian brain. A computational neural architecture instantiates the proposed model and is tested on a particular task of distal reward learning. Categorical Neural Semantic Theory informs the …
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Continuum mechanical analysis of space and time dependent deformation pattern of brain with blunt injury
Deformation of human brain due to acceleration impact has been widely accepted as the direct connection to the Trauma Brain Injury (TBI). However, the limitation of obtaining deformation data of TBI is a major obstacle to understanding TBI mechanism. This experiment mainly focuses on developing a …
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Feasibility study of trans-cranial Direct Current Stimulation in presence of Brain tumor
… solvers. However, the reliability of such models depends upon the accuracy with which the underlying anatomy has been modeled [1]. In earlier studies it has been shown that the current flow patterns within the brain are altered due to the presence of lesioned brain tissues[2]. Here we …
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Multi-spectral Deep Tissue Quantitative Photoacoustic Imaging
… Monte Carlo simulation was performed on a mouse brain model for optical fluence estimation at different imaging wavelengths, and the 3D optical fluence map was used for fluence heterogeneity correction. Moreover, an internal illumination strategy combined with a treatment catheter was applied to …
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Bioengineering Analysis of Traumatic Brain Injury
Traumatic brain injury (TBI) is a serious health concern affecting over a million people in the UK. Brain shift and herniation, which are closely related to severe disability or death, are important signs of abnormally elevated intracranial pressure (ICP) or space-occupying intracranial mass after …
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Evaluating Machine Learning Models of Sensory Systems
… of our field is to build stimulus-computable models of sensory systems that reproduce brain responses and behavior. The past decade has given rise to models that capture complex behaviors such as image classification, word recognition, and texture perception. Yet, there are known discrepancies …
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SEX DIFFERENCES IN HEAD IMPACT BIOMECHANICS AND QUANTITATIVE FUNCTIONAL DEFICITS DUE TO REPETITIVE LOADING IN HIGH SCHOOL SPORTS
… directions were applied to a finite element brain model to estimate tissue-level measures of injury such as strain and stress and regional sensitivity to head loading (Aim 4, Chapter 5). Soccer had the highest head acceleration event rate, and males consistently had higher rates than females. …
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The efficacy of holistic learning strategies in the development of church leaders in Mozambique : an action research approach
… “social” and “spiritual” learning and “whole-brained” learning. Broadly interpreting and applying the four-quadrant brain model of Herrmann (1994), and other models of the brain, my study seeks to understand whether, to what extent and how learning can be advanced by deliberately employing …
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The Biotechnological Applications of an Insect-Specific Alphavirus
… well as in a highly susceptible suckling mouse brain model. Structural analyses revealed that the chimeric viruses are indistinguishable from their pathogenic counterparts. Following immunogenicity and efficacy experiments, we demonstrated that EILV-based chimeras can induce single-dose …
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Simulation studies on X-ray imaging of brain parenchyma and tumors
… to image the tissues in the parenchyma of the brain and brain tumours in early stages. Aim of the presented research is to investigate whether CT could be used to image the soft tissue of the brain since this would provide an extremely powerful tool in the hand of the clinicians. CT due to its …
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Identification and Characterization of Mitochondrial DNA Variants in Alzheimer's Disease
… AD tissue. ATP demand is most prevalent in the brain; damage to OXPHOS could severely impair brain metabolism, thereby leading to a decline in cognitive function. Four out of five complexes in the OXPHOS pathway are partly encoded by mitochondrial DNA (mtDNA); thus, this may be a crucial site of …
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Swine applied ethology methods for a model of mild traumatic brain injury
… stressors lead to health problems. Traumatic brain injury (TBI) is defined as malfunctioning and pathology of the brain caused by external mechanical forces. This physical and psychological stressor may lead to long-term damage on both physiology and psychology mechanisms. Traumatic brain …