Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Brain drug delivery"”.
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Focused ultrasound-mediated drug delivery to the brainstem
<p>Brainstem gliomas are tumors that occur in the brainstem, the brain region that connects the brain to the spinal cord and controls vital body functions. The critical anatomic location of the brainstem precludes surgical intervention and limits the use of invasive therapeutic techniques. …
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Studio di formulazione e caratterizzazione di nanoparticelle a base di trimetil chitosano e sodio alginato per il rilascio mirato di farmaci
… chitosan (TMC) and sodium alginate (SA) as drug delivery systems able to interact with the sialic residues of the mucous membranes. The TMC has been synthesised in our laboratory slightly modifying literature procedure, and characterised by 1H-NMR spectroscopy. NPs were prepared with the …
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Supramolecular Structure-Enabled Delivery of Porphyrin to Glioblastomas Beyond the Blood-Brain Barrier
… However, the presence of an intact blood-brain barrier (BBB) within infiltrative tumor tissue restricts porphyrin delivery and, thereby, therapeutic efficacy. This thesis leverages the drug delivery advantages of porphyrin supramolecular chemistry to address this limitation through the …