Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Brain Regeneration"”.
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Brain regeneration in a hypoxic-ischemic mouse model
… a majority of cerebral palsy cases. During HI brain injury neurons, glia and endothelial cells are damaged and lose their function or die. But unexpectedly there are greater numbers of infants do not suffer lasting neurological impairment. One of the reasons may be the formation of new cells in …
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Towards an understanding of the role of Ca2+ signalling in neural stem cell activation
Regeneration of the adult human brain is a long time clinical challenge. The adult mammalian brain contains neural stem cells (NSCs) that are capable of brain repair, but they are mostly in a mitotically quiescent state. Identifying novel regulators of neural stem cell quiescence will provide more …
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The Glial Response to Focused Ultrasound-mediated Permeabilization of the Blood-brain Barrier: Evaluating the Potential Contribution of Microglia and Astrocytes to Pathology and Regeneration
… temporary permeabilization of the blood-brain barrier (BBB) for delivering therapeutics to the brain. FUS-mediated BBB modulation is known to activate microglia and astrocytes, which can exacerbate pathology or promote neuroprotection. I hypothesized that FUS induced a transient …
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MAPK and pro-inflammatory mediators in the walls of brain blood vessels following cerebral ischemia
… with disruption of blood flow to a part of the brain with rapid depletion of cellular energy and oxygen, resulting in ionic disturbances and eventually neuronal cell death [3]. The pathologic process that develops after stroke is divided into acute (within hours), sub-acute (hours to days), and …