Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Brain Connectome"”.
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Novel Implementation of Additive Manufacturing to Visualize the Human Brain Connectome
… to create real life models of the human connectome. The human connectome is a color coded map of the connections in the human brain where directions are indicated by colors and the density of connections are indicated by color intensity.</p> <p>There are several different algorithms for …
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Characterising the structural brain connectome in Alzheimer's disease and its relation to cognitive intra-individual variability.
… white matter (WM) degeneration and structural connectome disruptions measured by diffusion tensor imaging (DTI) as well as increased reaction time intra-individual variability (RT IIV) on neurocognitive testing. However, the relationship between these changes measured on these different …
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Exploring the Cephalopod Brain: Towards Mapping the First Whole Brain Connectome and Whole Animal Projectome of a Pygmy Squid
… They possess large, highly centralised brains for processing sensory information, higher cognitive functioning, motor control, and feeding. Cephalopods are known for their ability to solve problems in unique ways, displaying idiosyncrasies in prey/predator behaviours, courtship and …
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Advances in functional magnetic resonance imaging to facilitate brain research
Probing brain functions at laminar and columnar level provides opportunities in understanding local and remote neural circuits that are critical for cognition and behaviors. High field functional magnetic resonance imaging (fMRI) based on blood oxygenation level dependent contrast (BOLD) is one …
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Deterministic Barcoding of Neuron Identities through Multicolor Fluorescent Markers in C. elegans
Mapping the connectivity of neurons, or the brain connectome, with a clear identification of neuron types and functions is a complicated problem that hinders the development of potential therapeutic interventions. Without understanding the identities of neurons that have fundamental roles in …
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Circuit Mechanisms of Context-dependent Memory-based Action Selection
Brain structures such as the Striatum (vertebrates) and the Mushroom Body (MB) (invertebrates) are thought to carry out classical conditioning (Eichler et al., 2017; Heisenberg, 2003; Suri & Schultz, 1999). This process allows animals to associate conditioned stimuli (CSs) with rewards or …
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Investigating circuit and spatial heterogeneity of human brain tumors with patient-derived organoid models
… glioblastoma (GBM), are aggressive adult primary brain cancers with dismal prognosis. Both malignant cell heterogeneity and the influence of myriad cell types present in the tumor microenvironment, such as neurons, contribute to glioma progression. This dissertation represents a multi-pronged …
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Advanced Robust Statistical Learning Methods with Application in Healthcare and Manufacturing
… the need to understand the relationship between brain networks and phenotypes of interest in small-scale neuroimaging studies with limited sample size, I developed a flow-based generative model termed Disentangled Adversarial Flow or DAF for short, which leverages large-scale multi-source …
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Uncovering Dynamic Semantic Networks in the Brain Using Novel Approaches for EEG/MEG Connectome Reconstruction
… predictions of recent models of the semantic brain system, such as the hub-and-spokes model. In particular, we tackle different aspects of the hypothesis that a widespread network of interacting heteromodal (hub(s)) and unimodal (spokes) cortices underlie semantic cognition. For this purpose, …