Global ETD Search
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Showing 1 to 20 of 20 for “"Bovine Spongiform Encephalopathy"”.
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The Impacts of Food Safety Fears and Policy on International Trade: Trade Creation, Diversion, and Depression as a Result of Bovine Spongiform Encephalopathy
… of Agriculture announced the presence of Bovine Spongiform Encephalopathy (BSE) within a cow in the state of Washington. The announcement prompted the cessation of beef imports by the largest traditional beef trading partners with the United States, resulting in immediately realized losses …
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Exploring Novel Immunodiagnostics for Prion Disease
Prion Diseases, or Transmissible Spongiform Encephalopathies (TSEs), are rapidly progressive and fatal neurodegenerative diseases of mammals. TSEs of global importance include Creutzfeldt-Jakob Disease (CJD) in humans, Chronic Wasting Disease (CWD) in cervids, and Bovine Spongiform Encephalopathy …
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Using Saccharomyces cerevisiae to characterise the in vivo effects of exposure to the prion-curing drug Tacrine and the fungal metabolite gliotoxin
… such as Creutzfeldt-Jakob Disease (CJD) and Bovine Spongiform Encephalopathy (BSE). Fungal prions also exist, which provide a useful tool for studying the propagation of these non-mendelian genetic elements. Possibly the most widely-studied S. cerevisiae prion is [PSI+], which is the prion …
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Metabolic Profiling of Prions In The Gastro-Intestinal Tract
… <p>Prion diseases, also known as transmissible spongiform encephalopathies (TSEs), are a group of debilitating neurodegenerative disorders that affect both humans and animals. They can be spread by horizontal transmission as seen in chronic wasting disease in deer and elk population. In …
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ACUTE CELLULAR UPTAKE OF ABNORMAL PRION PROTEIN IS CELL TYPE AND SCRAPIE STRAIN INDEPENDENT
<p>Transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative diseases that include Creutzfeldt-Jakob disease, bovine spongiform encephalopathy and sheep scrapie. TSE disease pathology and mechanisms within the central nervous system (CNS) of an infected host largely remains …
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ACUTE CELLULAR UPTAKE OF ABNORMAL PRION PROTEIN IS CELL TYPE AND SCRAPIE STRAIN INDEPENDENT
<p>Transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative diseases that include Creutzfeldt-Jakob disease, bovine spongiform encephalopathy and sheep scrapie. TSE disease pathology and mechanisms within the central nervous system (CNS) of an infected host largely remains …
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Design and synthesis of constrained dipeptide units for use as β-sheet promoters
… (AD), Creutzfeldt-Jacob disease (CJD) and bovine spongiform encephalopathy. Understanding beta-sheet formation and the factors that stabilize beta-sheet structure may serve as a basis for future drug design. The extended structure of a beta-sheet can be stabilized by constrained amino acid …
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Structure determination of proteins and peptides in solution: simulation, chirality and NMR studies
… class of neurodegenerative diseases, known as Bovine Spongiform Encephalopathy (BSE), present in mammals, but not in avian species and it is caused from the conversion of cellular prion protein to the pathogenic misfolded isoform, accumulating in the brain in form of amiloyd plaques. In …
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Kinetics of Peptide Aggregation
… such as Alzheimer's and Parkinson's disease and bovine spongiform encephalopathy (BSE), which have no effective treatments or known cures. Pathogenic amyloids appear as nanometer sized "plaques" that self-assemble over time. The plaques usually are well-organized crystalline/fibrous structures …
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Identifying Genetic Factors of BSE Susceptibility
Bovine spongiform encephalopathy (BSE) is a transmissible, neurologic disease of cattle that decimated the cattle industry in many countries when it was discovered to be zoonotic. This disease is caused by a unique pathogen believed to be entirely composed of a misfolded, degradation-resistant form …
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Imaging of mice and men; adventures in multispectral imaging
… have gained notoriety due to recent outbreaks of Bovine Spongiform Encephalopathy (BSE) and the evidence that they can be transmitted between species, including to man. Exposure to BSE infected material has been shown to cause variant Creutzfeldt-Jacob disease in man. Prion disease is also used as …
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Three Essays on Agricultural Trade Policy
… The first essay estimates the impact of the 2003 Bovine Spongiform Encephalopathy (BSE) outbreak in the US on Japanese beef imports. I develop a source-differentiated demand system of fresh/chilled and frozen beef imports augmented with endogenous smooth transition functions. Results suggest that …
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Spatial spread of farm animal diseases
… an export ban on British beef following the bovine spongiform encephalopathy epidemic, the European Union required that the UK should have "An effective animal identification and movement recording system". The Cattle Tracing System (CTS) was introduced in September 1998, and the scheme was …
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Outlining different perspectives for accurate MS-based proteomics in processed matrices - a case study on European feed control
Since the outbreak of Bovine Spongiform Encephalopathy (BSE) in the 1990s, European legislation has restricted animal-derived protein in feed. However, current official control methods only partially ensure compliance. Mass spectrometry (MS) offers a promising approach to ensure food and feed …
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Identification of gene expression changes in Drosophila models of mammalian prion diseases
… prion diseases, such as scrapie in sheep, bovine spongiform encephalopathy in cattle and variant Creutzfeldt-Jakob disease in humans. Genetic prion diseases also occur in humans, which are associated with mutations in the prion protein (PrP) gene, such as genetic CJD (gCJD) and fatal …
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Quantifying the trade impact of non-tariff measures: Econometric and CGE Analysis
… the impact of foot and mouth disease (FMD) and bovine spongiform encephalopathy (BSE) on beef trade. I find that during and after a FMD outbreak, exporting countries substitute away from markets recognised as FMD-free toward lower value markets not recognised as FMD-free. Similarly, a country …
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The subcellular trafficking of the prion protein: Characterisation of the function of the PrPc N-terminus
Transmissible spongiform encephalopathies (TSEs) are degenerative diseases of the central nervous system in humans and animals, and include Creutzfeldt-Jakob disease (CJD) in humans, scrapie in sheep and bovine spongiform encephalopathy in cattle. These spongiform encephalopathies can manifest as …
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Conditional limit theorems for multitype branching processes and illustration in epidemiological risk analysis
… enable us to study the extinction phase of the Bovine Spongiform Encephalopathy epidemic in Great Britain, for which we estimate the infection parameter corresponding to a possible source of horizontal infection persisting after the removal in 1988 of the major route of infection (meat and bone …
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Estudio integral del análisis de la calidad y seguridad alimentaria con el fin de definir acciones estratégicas por parte de la industria agroalimentaria
… los últimos tiempos en la UE, la Encefalopatía Espongiforme Bovina. En el sector vacuno, cuya producción supuso en 2004 el 17,6% de la producción ganadera en España y el 24,41% en Europa, se espera que con los cambios en la Política Agraria Común, se incrementen las importaciones y en …