Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 28 for “"Botulinum toxin"”.
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Comparing the efficacy of botulinum toxin and CGRP antagonists for chronic migraine prophylaxis
Chronic migraines are a neurological disorder, which can be debilitating to patients and result in increased healthcare costs and disability-affected life years. Botox and CGRP antagonists are two drugs used as prophylactic treatments for chronic migraine patients who have failed other medications …
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Clostridium botulinum toxin development in refrigerated reduced oxygen packaged Atlantic croaker (Micropogonias undulatus)
… and film oxygen transmission rate (OTR) on toxin development by Clostridium botulinum in refrigerated raw vacuum packaged croaker fillets, and to determine if toxin development precedes microbiological and/or organoleptic spoilage. Raw croaker fillets were vacuum packaged in oxygen-permeable …
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Antikörper vermittelte sekundäre Non-Response in der Behandlung spastischer Bewegungsstörungen im Kindesalter mit Botulinum Toxin A
In der vorliegenden Arbeit wurde die klinische Bedeutung der Antikörperbildung gegen BoNT/A in der Langzeitbehandlung von pädiatrischen Patienten mit einer spastischen Bewegungsstörung untersucht. Hierfür wurden Serumproben von 110 Patienten mit Hilfe des "mouse phrenic nerve hemidiaphragm" Tests …
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Standardisierte und validierte Messinstrumente zur Evaluation der Therapie mit Botulinum Toxin A bei Kindern mit Zerebralparese
Zahlreiche Studien zur Botulinum Toxin A (BoNT/A) Behandlung bei Kindern mit Zerebralparese belegen die lokale Wirksamkeit des Therapieverfahrens. Die Gross Motor Funktion Measure (GMFM) evaluiert quantitative Veränderungen der grobmotorischen Funktion, während die Pediatric Evaluation of …
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Entwicklung und Reliabilitätskontrolle eines videogestützten Beurteilungsbogens bei Kindern mit spastischen Spitzfüßen unter der Therapie mit Botulinum Toxin A
Hintergrund: Seit Beginn der 90er Jahre wird Botulinumtoxin A zunehmend zur Behandlung spastischer Spitzfüße im Kindesalter eingesetzt. Eine genaue Beurteilung des Gangbildes bei Zerebralparesen war bisher nur durch aufwendige Verfahren möglich. Es wurde ein videogestütztes Verfahren zur …
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Does combining physiotherapy with Botulinum toxin type A injections improve the management of children with spastic cerebral palsy?
… but there are ranges of treatments from drugs to Botulinum toxin type A injections, massage therapy to surgery. The aim of this study is to look at two of these treatments, namely Botulinum toxin type A injections and physiotherapy to treat spastic CP. Botulinum toxin is widely used to reduce …
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Local Administration of Botulinum Toxin Type-B in the External Anal Sphincter of Horses Produces Transient Reduction of Peak Anal Pressure
Toxins produced by the Gram-positive bacteria Clostridium botulinum cause transient chemodenervation of mammalian muscle. The toxin binds to specific proteins within cholinergic presynaptic nerve terminals which regulate the release of acetylcholine in the synaptic space resulting is loss of muscle …
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The role of Ras-related C3 botulinum toxin substrate 1 (RAC1)-dependent pathway in the regulation of uterine function during early pregnancy
… studies revealed that RAC1 (Ras-related C3 botulinum toxin substrate 1), a pleiotropic signaling factor belonging to the Rho family of GTPases, is induced in the uterine stroma during decidualization and angiogenesis, suggesting a role for RAC1 in these critical processes. To address the …
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Acute and Chronic Effects of Botulinum Toxin Type-A on the structure and Function of the Quadriceps Femoris Muscles of New Zealand White Rabbits
Botulinum toxin type-A (BTX-A) injections have become a common treatment modality for a variety of neuromuscular disorders with the primary aim to relax spastic muscles, for example, in children with cerebral palsy, or following a stroke. Once injected, BTX-A prevents acetylcholine release at the …
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The Effects of Modified Atmosphere Packaging on Toxin Production by Clostridium botulinum in Raw Aquacultured Flounder Fillets and Fully Cooked Breaded and Battered Pollock Portions
… significantly extended shelf life. Prevention of toxin production by Clostridium botulinum is essential for processors of VAC and MAP refrigerated fishery products. The objective of this study was to determine if C. botulinum toxin development precedes microbiological spoilage and sensory …
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STOMACH CONTENT ANALYSIS OF BOTULISM-AFFECTED BIRDS IN LAKE MICHIGAN
… were collected and tested for the presence of botulinum toxin type E (BoNT/E) at the USGS National Wildlife Health Center. I compare the prey composition and prey sizes consumed by the birds that were collected. Additionally, I examine the diets of culled double-crested cormorants …
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O uso da toxina botulínica na correção do sorriso gengival: uma revisão de literatura
… consideração o desejo do paciente. A injeção da toxina botulínica é uma alternativa minimamente invasiva que está sedo cada vez mais utilizada para a correção do sorriso gengival. Com isso, o objetivo do presente trabalho monográfico foi realizar uma revisão de literatura sobre o uso da toxina …
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Delayed gastric emptying in Ivor Lewis Gastro-oesophagectomy
… into: patients receiving intra-operative pyloric botulinum toxin(BOTOX) injections and those without. Comparative analysis against DGE diagnosis was performed. To assess pathophysiology and a novel investigation, 65 patients from 01/12/2017 to 31/12/2019 had blood and breath sampled …
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Osteocyte Activity and Skeletal Muscle Relative Gene Expression Profiling After Short-term Muscle Paralysis
… 20-week-old female rats were injected with botulinum toxin A (BTX, n=12) in the right hindlimb muscles, while external control rats (CTRL, n=12) were similarly injected using a saline solution. Animals then underwent gait and digit analyses to quantify the degree of paralysis. One-week …
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THE APPLICATION OF RADIOFREQUENCY WAVES IN THE MANAGEMENT OF ORAL MAXILLOFACIAL PAIN
… therapeutic options, such as occlusal splints, botulinum toxin injections, or systemic pharmacotherapy, diathermy is generally well tolerated, non-invasive and associated with rapid symptomatic relief. However, the studies available are still limited and defined by considerable heterogeneity in …
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Skeletal adaptation to reduced mechanical loading
… maintenance of skeletal health in mice, using botulinum toxin (BTX) to induce muscle paralysis and hindlimb unloading to eliminate external loading on the hindlimbs, alone and in combination. BTX led to greater bone loss than hindlimb unloading, while the combination of interventions led to the …
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Skeletal adaptation to reduced mechanical loading
… maintenance of skeletal health in mice, using botulinum toxin (BTX) to induce muscle paralysis and hindlimb unloading to eliminate external loading on the hindlimbs, alone and in combination. BTX led to greater bone loss than hindlimb unloading, while the combination of interventions led to the …
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