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Showing 1 to 5 of 5 for “"Boronic Acid Derivatives"”.
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Synthesis and Application of Boronic Acid Derivatives
Boronic acids are attractive synthetic intermediates and have been shown to be effective as inhibitors of various enzymes. In this project, the overarching goal is the selective inhibition of a protease present in the mitochondria known as human ClpXP. To study the potential selective inhibition of …
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Photoredox C–C Cross-Coupling Reactions using Boronic Acid Derivatives
… as reagents in organic synthesis, the use of boronic acid derivatives to generate carbon-centred radicals remains elusive. This dissertation explores the utilisation of photoredox catalysis to generate carbon radicals from boronic acid derivatives and subsequently engage them in C–C …
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A synthesis of a homologous series of aryl mono- and diboronic acids
<p>Many attempts have been made to prepare aryl boronic acids and their esters which show a preferential affinity for tumor tissues for use in radiation therapy of neoplatic disorders (1,2). The data of Soloway, as extended and refined by Hansch and his coworkers, successfully correlates the low …
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SYNTHESIS AND CHARACTERIZATION OF HIGHLY FLUORESCENT TUNABLE AZABORINE PHOTO-INDUCED ELECTRON TRANSFER GLUCOSE SENSOR
… a biological system. Over the past decades, boronic acid derivatives such as <em>ortho</em>-aminomethyl phenylboronic acid have been utilized heavily in glucose sensing systems because of the strong binding affinity displayed by boronic acids to saccharides. This research project aims to …
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Synthesis and biological evaluation of functionalized benzoxaboroles as potential antimicrobial agents
Boronic acids are extremely valuable compounds that have applications in medicinal, and materials chemistry, and also as cross-coupling agents in synthetic chemistry. Boronic acids often function as inhibitors for various enzymes due to their unique electronic and physicochemical properties. …