Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Boolean Models"”.
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Mathematical modeling of macronutrient signaling in Saccharomyces cerevisiae
… called BoolODE for utilizing published Boolean models to generate synthetic datasets used to benchmark the performance of algorithms performing gene regulatory network inference from single cell RNA sequencing data.
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Understanding transcriptional regulation through computational analysis of single-cell transcriptomics
… which are based on two different formalisms, Boolean and autoregression frameworks respectively. BTR was shown to be useful for improving existing Boolean models with single-cell expression data, while SPVAR was shown to be a conservative predictor of gene interactions using pseudotime-ordered …
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The Potential Power of Dynamics in Epistasis Analysis
… by conducting an identifiability analysis of Boolean models of genetic pathways, comparing static and dynamic approaches. We also explore the identifiability of individual links in the pathway. Through these evaluations, we quantify how helpful the addition of dynamics is. We believe that a …
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Algebraic theory for discrete models in systems biology
… develops algebraic theory for discrete models in systems biology. Many discrete model types can be translated into the framework of polynomial dynamical systems (PDS), that is, time- and state-discrete dynamical systems over a finite field where the transition function for each variable …