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Showing 1 to 20 of 25 for “"Bone substitute"”.
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The design, synthesis, characterization, and mechanical testing of a novel degradable polymeric biomaterial for use as a bone substitute
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1995.
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The effect of Staphylococcus epidermidis on the pH and dissolution of substitute bone graft materials
… 11047 on the pH and dissolution of 5 different bone substitute materials. Part 1 – Measured the pH, calcium and phosphate of the culture medium in the presence and absence of the 5 bone substitute materials before and after autoclaving. Part 2 – Measured the pH of the culture medium in the …
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Fracture of the distal radius - outcome, primary surgery and treatment of malunion
… after a DRF. Instead of autologous iliac crest bone graft we used a slow resorbing bone substitute (Norian SRS®), consisting of hydroxyapatite, to fill the gap in combination with the TriMed system for fixation. We were able to improve forearm rotation, flexion/extension and radioulnar deviation …
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Treatment of enchondroma of hand using calcium sulfate and autobone grafting
… curettage followed by cancellous grafting. Auto-bone grafting should be done in general anesthesia to harvest from the iliac crest, and there is donor-site morbidity such as pain and possible infection. Therefore, we studied the efficacy of injectable calcium sulfate as bone substitute and …
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In-vitro-Biokompatibilitätstestung modifizierter Apatit- und Oxidkeramiken in der humanen Osteoblastenzellkultur
Presently available bone substitute materials are either bioactive with poor biomechanical stability or they show good biomechanical impact, but are bioinert. The aim of this study was to combine bioactivity of hydroxyapatite (HA) and the mechanical properties of bioinert ceramics like yttrium …
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In vivo Evaluierung eines Nanocomposites auf seine osteoinduktiven Eigenschaften im heterotopen Implantationsmodell
… eingesetzt. 3 Ratten erhielten das Composite NanoBone®, das Allograft Nexus IC® oder den Knochenwerkstoff betaGran®. 3 Ratten bekamen 2 Mal jedes Produkt implantiert. Es wurde Calcein grün appliziert. Die Ratten wurden euthanasiert und die Proben makroskopisch sowie histologisch ausgewertet. Die …
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Knochenaugmentation im Oberkieferseitenzahnbereich mit unterschiedlichen Ersatzmaterialien und Induktoren : eine klinische histomorphometrische Studie
… the oral implantology, one requires a sufficient bone-offer to insertion of implants. Today, a dentist can create a sufficient bone-camp with different bone substitutes. The aim of the present study was to evaluate bone formation following maxillary sinus augmentation using tissue-engineered bone …
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An investigation of blast wave transmission through rodent simulants
… surrogates include spheres made from tissue substitute, multi-material spheres with an inner core of tissue substitute and an outer shell of bone substitute, and ogive shaped articles made from tissue simulant. For simple shapes, the computational model has been shown to match experimental …
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Functional outcome and experiences concerning daily life after malunion of the distal radius and corrective osteotomy
… the fragment of the distal radius and the carpal bones and between the radius and the ulna is corrected. A common surgical approach is open-wedge osteotomy with volar plating. To increase stability at the osteotomy site, the osteotomy gap is often filled with a graft. The void can also be left …
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Biomimetica per l'ingegneria tissutale dell'osso
Reconstruction of bone is needed for high bone loss due to congenital deformities, trauma or neoplastic diseases. Commonly, orthopaedic surgical treatments are autologus or allogenic bone implant or prosthetic implant. A choice to the traditional approaches could be represented by tissue …
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Composite materials made of chitosan and nanosized apatite : preparation and physicochemical characterization
… and inorganic fillers are often found, e.g. bone, shell of crustaceans, shell of eggs, etc., the feasibility on making composite materials containing chitosan and nanosized hydroxyapatite were investigated. A new preparation approach based on a co-precipitation method has been developed. In …
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Assessment of Injection Behavior of Commercially-available Bone BSMS for Subchondroplasty Procedures
<p>Subchondroplasty is a procedure that utilized bone substitutes materials (BSMs) or bone cement to correct bone defects in the subchondral bone. The two main materials used to compose BSMs are poly-methyl-methacrylate (PMMA) and calcium phosphate cement (CaP). Currently, there is no optimal bone …
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In vitro inflammatory response evaluation of pre-degraded bioresorbable polymers
… field, and especially for the preparation of bone substitute constructs. However, there are reports of a delayed inflammatory reaction occurring months or years after implantation. Despite clinical studies demonstrating adverse reactions to bioresorbable polymers, there are few in vitro …
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Fundamental studies on ionomer glasses
… materials are currently being developed as a bone cement in joint replacement surgery. Initially, a simple quaternary (25i02-Al203-CaO-CaF2) glass was produced and was found to undergo minimal fluorine loss. This results in a glass whose composition is reproducible between batches. This …
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Preclinical Evaluation of 3D Printed Biomaterials for Repairing Critical-Size Bone Defects
… of patients each year suffer from non-healing bone defects secondary to trauma, cancer, osteomyelitis, or congenital anomalies. The standard of care for managing these cases necessitates bone reconstruction surgery. Although using autologous bone (autograft) or banked cadaveric bone (allograft) …
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Electron microscopic investigation of interfaces in materials for orthopedic applications
… of the prosthetic joint to the patient's bone, and second, the low generation of wear particles as the components of the prosthesis articulate against each other. This thesis is a study of both of these factors. First, the mechanism of bone apposition to hydroxyapatite (HA) coatings on …
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The Application of Melatonin and Platelet-Rich Plasma in the Development of a Bioactive Calcium Aluminate Bone Regenerative Scaffold
Over 500,000 bone graft procedures are conducted annually within the United States. Autografts contribute to donor site complications and disease transmission with allografts has been described. Many ceramics are only osteoconductive and are brittle, limiting their clinical use. Thus, the objective …
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Structural characterisation of apatite-like materials
… applications and has found application as bone substitute and implants coating due to the high similarity to the inorganic material of bone and tooth. Usually the HA lattice in living organism is substituted by different cations in order to help maintaining a normal metabolism. Once the …
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Effect of Mechanical Environment on the Differentiation of Bone Marrow Stromal Cells for Functional Bone Tissue Engineering
Bone is the second most transplanted tissue after blood and the need for bone graft materials continues to rise at an average annual growth rate of over 18%. An engineered bone substitute consisting of a bone-like extracellular matrix deposited on the internal pores of a resorbable biomaterial …
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Bone Marrow Stromal Cell Invasion and Bone Regeneration in Enzymatically-Degradable Osteoinductive Hydrogels
<p> Over the years, the repair of bone defect is an increasing challenge for reconstructive surgery. Due to disadvantage of autograft and allograft, including limit of bone supply, high morbidity and potential immune response, synthetic scaffold have been studied as a promising strategy for tissue …
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