Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Bone morphogenic protein (BMP)"”.
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EFFECTS OF OSTEOARTHRITIS AND INFLAMMATION ON MENISCUS CELL RESPONSE TO OSTEOGENIC PROTEIN 1 (OP1)
… project was to determine the response to the Bone Morphogenic Protein (BMP) family member, Osteogenic Protein 1 (OP1/BMP7) in meniscus cells. We have focused on the meniscus, because this tissue is highly susceptable to injuries which often fail to heal and lead to osteoarthritis (OA). OA is …
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Characterization and comparison of cell frequency, growth, and multipotential differentiation of adult mesenchymal stromal cells derived from equine bone marrow and adipose tissue
Equine bone marrow-derived mesenchymal stromal cells (MSCs) and adipose tissue-derived stromal cells (ASCs) were compared for frequency within their respective tissues, cell doubling characteristics and differentiation multipotential in culture based on histochemical staining and compositional …
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Bone morphogenetic proteins 9 & 10 in pulmonary arterial hypertension
… the pulmonary vascular endothelium. Mutations in BMPR2, which encodes the type-II bone morphogenic protein (BMP) receptor BMPR-II, explain the majority of heritable PAH. BMPR-II forms a signalling complex, with ALK1 and endoglin, specific to endothelial cells which maintains vascular quiescence. …
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Characterisation of BMP Processing and Signalling in Adipocytes
… to obesity and related cardiovascular diseases. Bone morphogenic protein (BMP) 8B, part of the Transforming Growth Factor-β (TGF-β) superfamily, is key in regulating energy balance via activating brown adipose tissue (BAT) thermogenesis, presenting a potential target for obesity treatment. …
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Osteogenic Scaffolds for Enhanced Graft-Bone Integration in Ligament Tissue Engineering
… tissue grafts (e.g., hamstring tendon) to native bone is slow and risks graft pullout. To circumvent these limitations, tissue engineering seeks to fabricate suitable biomaterials that could replace the entire ACL, stimulate regeneration of the ligament tissue, and integrate with host bone tissue. …
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Neural and Physical Niches Orchestrate Skeletal Remodelling and Promote Cartilage Regeneration
… nerve fibres. While several studies suggest the bone-catabolic nature of noradrenergic innervation in decreasing osteoblast activity and promoting osteoclastogenesis, there is little known on the development and function of skeletal cholinergic innervation. Therefore, the first goal of my …