Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Bone morphogenetic protein-4"”.
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Elucidating the role of bone morphogenetic protein-4 in regulating secondary injury mechanisms following traumatic spinal cord injury
… SCI in rats, we found that the active form of bone morphogenetic protein-4 (BMP4) is transiently and acutely upregulated after injury. BMP4 is a key signaling protein that regulates embryogenesis and neurodevelopment. BMP4 has also been implicated in modulating glial scarring and remyelination …
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Developing a stem-cell system of embryonic development organised by a morphogen signaling centre
… mesoderm, endoderm, and ectoderm are specified. Bone morphogenetic protein 4 (BMP4), secreted from the extraembryonic ectoderm is required for gastrulation to start whereby it activates downstream signaling molecules wingless inhibitor 3 (WNT3) and Nodal in a concentration dependent manner to …
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The effects of BMP4 on different in vitro models for mouse gastrulation and neural induction
Bone morphogenetic protein 4 (BMP4) is a signaling protein involved in several key developmental processes, including gastrulation and neural induction. Gastrulation is an event that changes the topology of the embryo, organising a single layer or ball of cells into the three primordial germ …
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Development of a reversible quiescence model to identify signals enabling glioblastoma cancer stem cell transition between active and quiescent states
… develop a reversible GSC quiescence model using Bone Morphogenetic Protein 4 (BMP4) in combination with Fibroblast Growth Factor 2 (FGF2) for different durations (3, 4), to model different depths of quiescence. BMP4 plus FGF2 treatment results in cell cycle exit, downregulation of protein …