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Showing 1 to 20 of 50 for “"Bone metabolism"”.
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The Role of Claudins in Bone Metabolism
… problem in the U.S., is characterized by low bone mass and structural deterioration of bone tissue. Since the imbalance between bone formation and bone resorption during bone remodeling has been documented to be a major factor in the pathogenesis of osteoporosis, it is crucial to identify …
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Alteration of bone metabolism in OLETF rat
"Purpose: OLETF rat is a model of Type II DM. Bone metabolism has influenced with hormones, growth factors, and cytokines that orchestrate the activities of both osteoclast and osteoblast cells. Type II DM influences bone metabolism and Neuropeptides-leptin and NPY2 receptor’s in hypothalamic …
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Altered bone metabolism in the protein deprived rat
… as the 1920's it was realised that the skeletal metabolism in protein-calorie malnutrition was deranged. Notwithstanding this, there is still to date inadequate understanding of the mechanisms by which these skeletal changes are brought about. This is partly due to the fact that the research …
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Impact of genetics and phosphorous nutrition on bone metabolism
<p>Phosphorous (P) is essential to bone growth and maintenance; however, little research has focused on the genetic mechanisms controlling P utilization. Thirty-six pigs from 2 sire lines known to differ in bone structure (heavier-boned, HB, and lighter-boned, LB) were assigned to three diets for 2 …
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The Effect of Low Dose, Long Term Calcium Infusions on Bone Metabolism
… studies have recently shed some light on the bone formation rates in various disease states. Using Ca-45, Bauer et ale (1), in Sweden, and Heaney (2), at the National Institute of Health, devised a method of determining rate of calcium deposition in various diseases. By their technique …
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Association of genotype with bone metabolism, skeletal adaptation and stress fracture injury occurrence
Positive changes in bone metabolism, structural characteristics, size and mass are commonly associated with weight-bearing exercise. Despite this, negative effects of exercise on bone phenotypes, such as stress fracture injuries have been reported. Little is known about the extent of the genetic …
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Characterization Of The Skeletal Phenotype In Idua-W392X Knock-In Mice: Bone Metabolism Biomarkers
… and short stature. Skeletal biomarkers of bone formation and bone resorption were compared in wild-type, heterozygous, and IDUAW392X mice. To investigate osteoblast activity, levels of the bone formation marker Procollagen type I N-terminal propeptide (PINP) were evaluated. To investigate …
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The effects of chrysin on osteoclastogenesis in RAW264.7 murine macrophages and bone metabolism in Sprague Dawley rats
Bone is regarded as a metabolically active tissue that is constantly being reformed and resorbed by osteoblasts and osteoclasts. Abnormal increases in osteoclast productivity can result in bone deterioration. Receptor activator of nuclear factor-kappa B (RANK) signalling is critical for function …
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Effect of Estrogen, Excess Dietary Phosphate and Their Interaction on Bone Metabolism in Mature and Aged Female Rats
Made available in DSpace on 2015-05-13T15:26:56Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7709186.PDF: 5042817 bytes, checksum: 781d1606dfab84560f4d18a65f8695d4 (MD5) Previous issue date: 1976
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Effects of inulin supplementation on markers of mineral and bone metabolism and the gut microbiota in hemodialysis patients
… disease (CKD) have some degree of mineral and bone disorder (MBD), which is associated with higher morbidity and mortality, specifically from cardiovascular causes. Despite the pharmacological treatment for MBD, its prevalence remains high, especially for patients with kidney failure undergoing …
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Bone metabolism abnormalities in children with epilepsy at Red Cross War Memorial Children's Hospital, Cape Town, South Africa
… medications and biochemical markers of bone metabolism has revealed inconsistent results. Most of these studies were undertaken in Europe and America where the burden and the associated comorbidities are different to the ones in Africa. Methods: A hospital based case control study was …
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Aseptic loosening around total hip and knee arthroplasty is linked to plasma microRNA
… and that these differences can be linked to bone metabolism leading to osteolysis and aseptic loosening. Our study investigated the potential regulatory roles miRNA have in the development of osteolysis and aseptic loosening around hip and knee arthroplasty. Firstly, a retrospective …
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Estrogen, energy, and bone: a life history approach to understanding skeletal phenotypes
Bone is affected by estrogen throughout the lifespan. Changing concentrations of estrogen shape the structure of bone and influence bone maintenance processes over time. Understanding bone health in women as both a function of earlier life experiences, as well as a reflection of current …
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The Interaction of Equol and Genistein on Estrogen Dependent Tumors and Bones in Ovariectomized Athymic Nude Mice
… on human estrogen dependent tumor growth and bone development in ovariectomized athymic nude mice. In the first study, the experiments were conducted to evaluate the effect of equol alone on the T47D human breast cancer cells and bone metabolism. At the physiological concentration levels, 100 …
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Analysis of biological pathways, associated with orthodontic force, using multiplex arrays
… IL-10, TNF), tissue (MMP-9, TIMP-1 and 2) and bone metabolism (RANKL, OPG) biomarkers were measured. Results –IL-1β, IL-8, TNFα, MMP-9 increased in canine tension sites and TIMPs 1 and 2 from T2-T4, canine compression sites showed increases in IL-1β and IL-8 only at T2, MMP-9 at T3 and T4 and …
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Effects of Jump Training on Bone Mineral Density in Young Adult Females
<p>Physical activity is critical to bone health. However, not all physical activity has optimum effect on bone health and metabolism. The purpose of this study was to determine the effects of a short term progressive jumping protocol on bone mineral density in college age Asian females. Sixteen …
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Personalising Inhaled Corticosteroid Dose Response in Persistent Asthma
… any detrimental effect of an ICS dose ramp on bone metabolism, an important potential long-term adverse effect of higher ICS dosing.<br/><br/>The discussion draws together all the results obtained in relation to ICS dose response in asthma, and how these apply to current clinical practice for …
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Sympathetic Nerve Modulation of Joint Pathology in Adjuvant-Induced Arthritis
… were then evaluated for changes in lymphocytes, bone area, osteoclasts, cartilage, pannus, sympathetic nerves, and bone volume. Results: At 21 days, the drug treated group showed a significant improvement in lymphocytes, cartilage and bone volume. There was also a decrease in pannus and …
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Der Einfluss von Phytoöstrogenen, mehrfach ungesättigten Fettsäuren, Vitamin D und K auf den Knochenstoffwechsel und die Mikroarchitektur des Knochens
… D and K were found to have a positive impact on bone in vitro and partially in vivo. In the present study effects of a combination of genistein, polyunsaturated fatty acids and vitamin D and K on bone metabolism and microarchitecture of bone in intact and overiohysterectomized dogs were …
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