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Showing 1 to 20 of 125 for “"Bone mass"”.
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Bone Mass from Childhood to Adulthood
Attaining high peak bone mass (PBM), the highest bone mass value in life which is reached in young adulthood, is important as it reduces the risk of having low bone mass in old age69, 80. Low bone mass is associated with high fracture risk3, 60. Osteoporosis is the result of bone loss, a …
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Bone Mass Preservation and Fracture Risk Assessment with Bisphosphonate Therapy During Spaceflight
… explorers include cardiovascular deconditioning, bone loss, muscular atrophy, and impairment of neurovestibular and sensory function. The great loss of bone due long-duration spaceflight increases fracture risk, jeopardizing the success of the mission and postflight recovery. Bisphosphonates may …
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SirT1 regulates bone mass in vivo through regulation of osteoblast and osteoclast differentiation
… we show that SirT1 is an important regulator of bone mass in vivo: SirT1 whole-body knockout mice display significant bone deficiencies that are associated with decreased osteoblast and increased osteoclast numbers. Further, osteoblast (ObKO) and osteoclast (OcKO) specific SirT1 knockout mice …
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Role of the RUNX2 rs59983488 variant in bone mass determination and fracture risk in Malta
… disease which is characterised by a reduced bone density (BMD) and compromised bone microarchitecture, leading to an increased fragility fracture risk. The Runt-related Transcription Factor 2 (RUNX2) protein encoded by the RUNX2 gene is involved in the maturation and differentiation of …
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Bone growth during puberty and the effects of exercise and calcium on bone mass accrual
… significant contributions to the variance in bone mass. To optimise the development of bone it is important to identify and promote factors that may have a positive effect on bone mass accrual. Two lifestyle factors that may enhance bone mass accural are calcium and exercise. The focus of this …
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Peak Bone Mass, Lifestyle Factors and Birth Weight: A study of 25-year old women
Background: Osteoporosis is a common bone disease, which does not give symptoms until the ultimate outcome, the fragility fracture occurs. Regulation of bone mass is controlled by genetic, environmental and nutritional influences. Peak bone mass, defined as the maximum bone mass accrued, is usually …
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The Relationship between Lower Extremity Bone Mass and Body Mass Index in a NHANES Adolescent Population
<p>The effect of body mass index (BMI) on bone mineral content (BMC) among adolescents has been researched yielding mixed results. This study explored the relationship of left lower extremity (LLE) BMC on BMI across the spectrum of weight in a large nationally representative group of adolescents. …
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Diet and Bone Mass In British Children: An Examination of theInfluence of Breastfeeding, Fruit and Vegetable Intake, and Protein Consumption
… and adolescence represent critical times for bone growth and the accretion of bone mass. Children who fail to maximize their bone mass during this period may face an increased risk of osteoporosis, a skeletal disorder that is marked by low bone mass, bone deterioration and increased fracture …
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Modeling the Long Term Effects of Alendronate on Bone Mass Preservation of the Femur with Articular Surface and Total Hip Replacements
Calculating femoral bone density changes after hip arthroplasty is of interest to researchers and clinicians for predicting the longevity of the prosthetic implant and the surrounding bone. Recently clinicians have been administering bisphosphonate drugs in an attempt to reduce the bone resorption …
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Contributions of physical activity, body composition, age, and nutritional factors to total and regional bone mass in premenopausal aerobic dancers and walkers
… were to determine whether exercisers had greater bone mass than non-exercisers, and among exercisers, whether aerobic dancers had greater bone mass than walkers. Another purpose was to identify body composition and nutrition factors related to total and regional bone mass in physically active and …
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Non-autonomous regulation of bone mass accrual and the role of T-cell protein tyrosine phosphatase in the bone regulation of insulin sensitivity
… constant remodeling to renew itself and maintain bone mass. It is subject to regulation from both hormones produced in peripheral tissues and neuronal control by the nervous system. Recent studies have shown that the skeleton is also an endocrine organ, releasing the hormone osteocalcin that …
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Correlation of Osteoporosis and Obesity
… skeletal disease characterized by a reduction in bone mass. The relationship between obesity and osteoporosis has long been investigated. It is a widely held dogma that interventions lowering the risk of obesity may generally result in higher risk for osteoporosis. It is also believed that …
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The Impact of Acute and Chronic Weight Restriction and Weight Regulation practices on Physiological, Osteogenic, Metabolic and Cognitive Function in Elite Jockeys
… Study One: The effect of a 4% reduction in body mass in 48 hours on physiological and cognitive function was assessed through performance on an incremental cycle ergometer test to volitional exhaustion and a computer based cognitive test battery. Study Two: Bone mass was compared between jockeys …
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Bone fracture toughness of estrogen deficient rabbits
Bone mass is commonly used as an indicator of fracture risk. It has been shown in numerous studies that bone loss causes increased bone fragility and risk of fracture. It has also been shown that 50% of patients with osteoporotic vertebral compression fractures have the same bone mass as normal age …
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The Role of Wnt Signaling in Bone Mechanotransduction
… characterized by increased fracture risk and low bone mass. In skeletal tissue, canonical Wnt signaling is a critical regulator of bone mass, and dysregulation of the Wnt pathway has been implicated in numerous skeletal displasias. Some components of the Wnt signaling pathway have a clear role in …
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