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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 76 for “"Bone Remodeling"”.
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Trabecular bone remodeling around implants
Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1986.
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Pharmacological manipulation of fracture healing and bone remodeling
… more technically oriented orthopedic surgery. Bone healing and physiological skeletal remodeling involve a complex set of regulated signaling pathways that control the formation of new bone matrix and the resorption of damaged bone at the disease or injury site. Pharmaceutical substances, both …
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Trabecular topology : computational structural design inspired by bone remodeling
Bone remodeling is the process by which the internal morphology of bones in a healthy person or animal will adapt to the loads under which it is placed. This process makes bone stronger and performs better under daily loadings. It also gives a special topology to the trabecular bone. This thesis …
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Seasonal and Anatomical Variation in Compact Bone Remodeling in the Adult Sheep
… <p>SEASONAL AND ANATOMICAL VARIATION IN COMPACT BONE REMODELING IN THE ADULT SHEEP</p> <p>Joseph Calcagno</p> <p>In order to determine whether ovine compact bone is suitable for study of osteoporosis, the remodeling parameters of the untreated animal must be fully characterized. Ovine compact …
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Muscular Strength Training Modifies Regulation of Bone Remodeling: Inferences From Serum Biomarkers in Young Women
Biochemical markers of bone turnover allow inference of the events occurring at the bone tissue level and may detect changes in bone cell activity earlier than densitometric technologies. Serum concentrations of receptor activator for nuclear factor kappa-beta ligand (RANKL), osteoprotegerin (OPG), …
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Survival, primary stability and bone remodeling assessment of cementless sockets. An appraisal of Wolff's Law in the acetabulum
Contains fulltext : 155620.pdf (Publisher’s version ) (Open Access)
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Bone mineral density, bone remodeling, insulin-like growth factors, hormone replacement therapy, and exercise training in postmenopausal women
Osteoporosis is a condition of reduced bone mineral density (BMD) resulting in an increased susceptibility to bone fractures. The purpose of this study was to determine the effects of 12 months of weight bearing and resistance exercise on BMD, bone formation, measured by serum osteocalcin (OC) and …
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Dietary calcium and cation-anion difference influences calcium status and bone remodeling in exercising and sedentary Arabian horses
… exercise are two manageable factors that affect bone remodeling. Experiments were designed to test the hypothesis that bone density and calcium status would be affected by conditioning and deconditioning, and by dietary Ca and cationanion difference (DCAD). In experiment one, 12 Arabian horses …
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The Effects of Bisphosphonates on Bone Remodeling: Analysis of Microdamage Targeting by BMUs, BMU Velocity and Crack Surface Density
Studies have indicated that microdamage in the bone matrix both activates and "steers" BMUs (Basic Multicellular Units, the groups of osteoclasts and osteoblasts that resorb and form bone respectively) toward the damage in order to replace damaged bone with new, mechanically sound bone. Also, …
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An Investigation of Humeral Stress Fractures in Racing Thoroughbreds Using a 3D Finite Element Model in Conjunction with a Bone Remodeling Algorithm
… a 3D finite element model in conjunction with a bone remodeling algorithm. Nine muscle forces and two contact forces were applied to the 3-dimensional finite element model, which contains four separate load cases representing fore-stance, mid-stance, aft-stance, and standing. Four different …
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Mechanically-Induced Osteocyte-Th17-Cell Signaling and Osteoclastogenesis
… mechanical loading can lead to microdamage in bone tissue. In order to prevent accumulation of microdamage, a repair mechanism known as targeted bone remodeling removes the damaged bone tissue and replaces it with new bone matrix.|Osteocyte apoptosis has been associated with fatigue induced …
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The Effect of Ethanol on Bone Histomorphology
<p>The effect of ethanol on bone histomorphology was studied using an isocaloric liquid pair feeding system to administer equal amounts of essential vitamins and nutrients to control and ethanol animals.</p> <p>A bone remodeling sequence was induced in the lower right mandible by removal of the …
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Characterizing Bone Turnover in Osteoarthritic Bone Marrow Lesions in Human Knees Using Tetracycline Histology
Bone marrow lesions (BMLs) are a hallmark sign of osteoarthritis (OA) associated with clinical symptoms of pain and pain progression. Based on previous literature, BMLs are likely centers of increased bone remodeling. Currently, there is no consensus as to what defines a BML outside of its …
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Effects of Marathon Training on Male and Female Femoral Stress Fracture Risk
… and muscle activation patterns that influence bone remodeling may cause this observed difference in stress fracture occurrence. The goal of this thesis was to develop a finite element model of the femur during marathon training, then determine if marathon training affected bone properties of …
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Vascular and Mechanical Changes in Bone in Response to Chronic Ischemia and Mechanical Loading
… of ischemia and mechanical stimulation on bone remodeling. An immunohistochemistry protocol for vessel marking in bone was also developed. Ischemia was induced in a mouse model to determine vascular and mechanical property changes in bone in response to hypoxia, and mechanical …
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Bone Mineral Density Analysis for Evaluation of Cervical Vertebral Maturation
… include all factors that may be involved in bone maturation. For instance, the current CVM cannot account for changes of bone mineral density (BMD), which result from active bone remodeling during growth. Thus, the objective of this study was to describe bone density changes in the cervical …
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An Investigative Study Into the Relationship of Bone Morphogenetic Protein Antagonist Expression and Osteocyte Density by Region and Quadrant
… and cell behavior and viability with respect to bone remodeling and bone behavior is an exciting area of orthopedic research. The purpose of this study was to investigate the relationships between BMP antagonist expression and osteocyte density, lacunar densities and osteocyte viability in …
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Influência clínica e tecidual do diazepam no periodonto de sustentação durante o movimento ortodôntico
… an important role as intracellular mediator of bone remodeling induced by mechanical stress. The sample consisted of thirty-six guinea pigs (Cavia porcellus), 9 weeks of age, ranging in weight from 400 to 450g, divided into control group, placebo group and experimental group. ln the …
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Determination of denning bear isolate and its effects on non-denning guinea pigs
… Anabolic functions such as protein synthesis and bone remodeling continue. Female bears complete gestation, parturition and lactation.
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Regulation of Breast Cancer Cells’ Bone-Metastatic Potential by Mechanically Stimulated Osteocytes
Bone metastasis, the migration of cancers to the bone, occurs in 65-75% of patients with advanced breast cancer and significantly increases patients’ morbidity and mortality. The bone-metastatic cancer cells interact with cells in the bone to disrupt the bone remodeling balance, causing reduced …
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