Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 5 of 5 for “"Bone Fracture Healing"”.
-
Predictive modelling of the form and development of bone fracture healing
… of this study that the rate and formation of bone healing can be modelled mathematically and computationally, respectively, based on mechanical stimuli induced by the relative motion between bone fragments. To argue this case, the following hypotheses are tested; 1) the relationship between …
-
Combinatorial Roles Of Skeletal Cell Yap And Taz In Bone Growth, Remodeling, And Repair
During bone growth, remodeling, and fracture repair, skeletal lineage cell responses require the coordinated activation of multiple transcriptional programs. As defective genetic regulation of bone formation leads to both developmental and metabolic skeletal diseases, identifying and characterizing …
-
Elucidating Cause-Effect Relationships between Extracellular Matrix Signaling and Mesenchymal Stem Cell Differentiation
… by a range of environmental stimuli. MSC-based bone regeneration strategies would benefit from the identification of scaffold material properties which intrinsically promote osteoblast lineage progression. The aim of this work was to contribute to the understanding of elucidating cause-effect …
-
Towards an autologous tissue engineering construct for craniofacial bone repair
Patients with critical-size bone defects, as a result of trauma, congenital malformations or tumor resections, generally have limited healing without clinical intervention. The autograft is the current standard of care for repair of these defects due to capacity for osteointegration and …
-
The Role of Bisphosphonates and Osteoblast Lineage Cells in Promoting Osteogenic and Angiogenic Processes Necessary for Bone Repair
<p>Bone is a dynamic organ that readily undergoes bone formation and remodeling in response to its mechanical environment. This response is accelerated during injury such as full fracture and or stress fracture, where woven bone must rapidly form for successful repair and restoration of mechanical …