Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 61 for “"Bodipy"”.
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MODIFIED BODIPY PROBES TO EXPLORE PEROXISOME FUNCTION
This research aims to use fluorescent BODIPY probes to measure biological function within a plant cell. In particular developing BODIPY fluors with emission at near-infrared and long wavelength that provides considerable benefit for specific organelle monitoring will be explored. The work described …
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SYNTHESIS OF NOVEL BODIPY LIBRARIES AND THEIR APPLICATION IN BIOIMAGING
… libraries as chemical tool box based on BODIPY fluorophore. These novel BODIPY libraries were then carried out in both unbiased in vitro screening and cell-based screening systems. Novel sensors towards fructose, glutathione, date-rape drug-GBL, as well as neural stem cells, were …
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Boron Functionalization of BODIPY Dyes, and Their Evaluation as Bioimaging Agents
BODIPY, also known as “porphyrin’s little sister,” belongs to a class of fluorescent dyes. It contains a dipyrromethene π-system with a disubstituted boron atom. The basic 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) is known for its numerous useful applications in the fields of biology and …
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Synthesis, Characterization, and Evaluation of Novel BODIPY Dyes With Theranostic Applications
Boron dipyrromethene (BODIPY) dyes, have garnered much attention in recent decades due to their enticing photophysical properties and their bioimaging applicability. Despite the progression of this field, the development of BODIPY based anti-cancer agents and radioimaging dyes has seen little …
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Synthesis and Characterization of Red and Near-Infrared BODIPY-based fluorophores for various Biological Applications
… better known as BODIPY® dyes, have attracted considerable attention due to their intriguing physicochemical and spectral properties, including high absorption coefficient, fluorescence quantum yield and good photochemical stability. Despite the recent progress …
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Electrochemical and spectroscopic studies of bodipy dyes and nanostructured electrodes for solar energy harvesting and conversion
… (1) electricity using boron dipyrromethene (BODIPY)-thiophene- triphenylamine (TPA) dye-sensitized solar cells, (2) hydrogen fuel using an unbiased Z-scheme tandem cell, and (3) carbon-free fuels by reducing atmospheric CO2 in the presence of water. Nanostructured electrode materials are used …
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Analyse von DNA- und RNA-Modifikationen durch Fluoreszenz-Postlabeling mit BODIPY und Kapillarelektrophorese mit Laser-induzierter Fluoreszenzdetektion
… Markierung mit einem Fluoreszenzfarbstoff (BODIPY-FL-EDA), sich anschließender Trennung mit mizellarer elektrokinetischer Chromatographie und Laser-induzierter Fluoreszenzdetektion (CE-LIF). Zur Methodenentwicklung wurden sowohl synthetische Standardverbindungen der Modifikationen, …
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Synthesis and characterization of BODIPY-α-tocopherol : a new ligand to explore the intracellular transfer of Vitamin E
… of vitamin E with a thienyl derivative of BODIPY that is excited and fluoresces at longer wavelengths (Aex = 561 nm, Aem = 570 nm) is in development.
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A. Discovery of novel reactivity under the Sonogashira reaction conditions B. Synthesis of functionalized BODIPYs and BODIPY-sugar conjugates
… these two new reactions were investigated. B. BODIPY core was functionalized with various functional groups such as nitromethyl, nitro, hydroxymethyl, carboxaldehyde by treating 4,4-difluoro-1,3,5,7,8-pentamethyl-2,6-diethyl-4-bora-3a,4a-diaza-s-indacene with copper (II) nitrate trihydrate …
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(A). Regulation of B-/Z-DNA transition in modified oligonucleotides; (B). Synthesis of cationic BODIPY analogues for antimicrobial and anticancer applications
… oxygen generation experiments suggested that BODIPY 111 is ~2.5 times more efficient with respect to Rose Bengal (RB) in generating singlet oxygen. However, based on the cell-culture experiment, BODIPY 111 treated culture plates showed only slight reduction in CFUs compared to Rose Bengal and …
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Advanced Fluorescence Lifetime Imaging and Spectroscopy Techniques for Biological Samples
… were conducted on a fluorescent molecular rotor, BODIPY-Ci2, which was used to measure the intracellular viscosity. BODIPY-C12 is insensitive to the surrounding polarity using solvatochromic methods. It was demonstrated that the fluorescence lifetime of BODIPY-Ci2 in methanol/glycerol mixtures is …
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Design, synthesis and characterization of photocage molecules for light-activated release: Applications in polymer chemistry and phototherapeutics
… dissertation involves the development of new BODIPY photocages, advancing the properties of those photocages with structural modifications and extending the scope of those photocages with different leaving groups uncaging for better activity and releasing ability within the living cells. In …
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Dipyrrin complexes and their uses as self assembling materials
Several series of BODIPYs bearing mesogenic substituents were synthesised and their fluorescence and liquid crystal properties were characterized. Each compound prepared consisted of one BODIPY fluorophore and one, two or three mesogenic units based primarily on a cyanobiphenyl core. Initially, the …
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Screening of algal cells using microdroplet technology
… encapsulated in microdroplets were stained with BODIPY 505/515. The diffusion of the dye to and from the droplets was studied by fluorescence imaging. Furthermore, the BODIPY 505/515 fluorescence of the droplets was detected with the laser-induced fluorescence detection platform. Several …
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Synthesis, Monitoring, and Molechanical Action of Light-Driven Motorized Nanomachines
… light-driven motor, four adamantane wheels, and BODIPY fluorophores for their tracking by Single-Molecule Fluorescence Spectroscopy (SMFM). Through a series of iterations, the nanocars were optimized such that the motor keeps its fast rotation frequency in the presence of BODIPY. The high quantum …
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Fluorescence Off-On Sensors for F-, K+, Fe3+, and Ca2+ Ions
… Chapter IV describes the development of a novel BODIPY-based fluorescence turn-on Fe3+ sensor (FeS). FeS is a conjugate of two moieties, a BODIPY platform serving as the fluorophore and a 1,10-diaza-18-crown-6 based cryptand acting as the Fe3+ recognition moiety. FeS displays good selectivity, …
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A Multiplexed, Multi-scale Optical Imaging Platform to Quantify Tumor Metabolic Heterogeneity
… -Bora-3a,4a-Diaza-s-Indacene-3-Hexadecanoic Acid (Bodipy FL C16), a long chain saturated fatty acid is taken up by the cell and undergoes beta oxidation similar to native fatty acids. More recently, GWHT has begun combing these fluorescence agents for in vivo use to provide a wholistic …
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Light Harvesting using Metal-Organic and Organic Sensitizers in Hybrid Solar Cells: Synthesis, Characterisation and Application
… the NIR region with a single sensitizer, novel BODIPY dyes with excellent optical properties were designed and synthesised. We prepared BODIPYs with donor-groups to extend the delocalized system and integrated a meso-ethynyl bridge between the BODIPY core and the anchoring group to improve the …
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