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Showing 1 to 10 of 10 for “"Blutpumpe"”.
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Implantierbares elektromechanisches Blutpumpensystem zur langfristigen partiellen Herzentlastung
Nowadays, Ventricular Assist Devices (VADs) have mostly been employed as bridge to transplantation. A new field of application for VADs represents the support of the failing heart function with the aim of heart recovery, "bridge to recovery". This dissertation describes the development of a …
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Numerische Simulation der Strömung in Miniaturkreiselpumpen zur Blutförderung
New operation techniques on patients undergoing cardiovascular surgery or short-term ventricular assistance have lead to the development of a new generation of blood pumps with minimal size. This development is mainly focussed on hydraulic performance and biocompatibility. This thesis covers the …
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In-vivo-Implantation der Mikrodiagonalpumpe II beim Kalb : Hämodynamik und Hämolyse
Due to the increasing number of patients suffering from end-stage heart failure and the decreasing number of heart transplants the search for alternative treatment strategies is intensified. Artificial blood pumps may be used to bridge patients to transplant or might even be implanted as …
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Tierexperimentelle Untersuchungen zu Praktikabilität und Hämokompatibilität einer miniaturisierten extrakorporalen Membranoxygenierung
During treatment on an intensive care unit a severe complication of shock, sepsis or pneumonia is the development of ARDS (acute respiratory distress syndrome). An aggressive ventilation strategy is necessary to prevent hypoxemia but causes further damage to the lungs. The ventilator-induced lung …
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Evaluation eines Hemoresistometers
The development of blood pumps for use in heart surgery has to fulfill different demands. On the one hand there is technical performance, on the other hand there is low rate of complications. The technical performance can be tested without difficulty by in-vitro tests. Estimation of mean …
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Einfluss von hyperthermen Oberflächen auf Humanblut
In order to estimate the impact of exposure of human blood to elevated surface temperatures in blood-conducting systems, detailed data is required. Therefore, titanium alloy housing dummies were immersed in 25 ml heparinized human blood. The dummies were constantly tempered at specific temperatures …
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Implantable electromechanical displacement blood pumps : systematic design and validation methods
Blood pumps are developed for different clinical indications, such as cardiopulmonary bypass, extracorporeal membrane oxygenation, ventricular assist (bridge to recovery, bridge to transplant, destination therapy) or heart replacement. The REMATCH trial has demonstrated that mechanical circulatory …
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Die Mikrodiagonalpumpe : tierexperimentelle Untersuchung eines Linksherzunterstützungssystems unter besonderer Berücksichtigung des Thromboembolie-Risikos
Due to the discrepancy between the number of available donor organs and patients waiting for heart transplantation after suffering from end stage heart failure, intensive research has been undertaken to find alternatives to bridge time to transplantation or as live saving therapy. Over the last …
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Numerical simulation of platelet adhesion, activation and aggregation : application to Taylor-Couette systems
Heart attack and stroke are among the leading causes of death in industrial nations but the number of candidates needing a transplant exceeds the number of transplants performed. Due to this chronic shortage, blood pumps are needed to deliver appropriate hydraulic performance while maintaining …
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Kenngrößenorientierte Beurteilung von Rotationsblutpumpen diagonaler Bauart mittels numerischer Strömungssimulation
The aim of this work was to analyse the flow phenomena within the implantable rotary blood pump “MikroDiagonalPump” (MDP) by means of Computational Fluid Dynamics (CFD). In the first part, a method has been developed to evaluate different pump geometries and impeller variations in a standardised …