Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 33 for “"Bloodstream infections"”.
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Infection Control: Reducing Hospital Acquired Central Line Bloodstream Infections
<p>Hospital-acquired infections are a leading cause of morbidity and mortality in neonatal intensive care units (Ceballos, Waterman, Hulett, & Makic, 2013). It’s estimated that each neonatal bloodstream infection costs about $35,000 and adds about two weeks to a baby’s hospital stay (Akron's …
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Digital amplification for pathogen detection in bloodstream infections from whole blood
… is essential for control and treatment of bloodstream infections. Sepsis, a diagnostic challenge of blood stream infections, causes thousands of deaths each year. The gold standard for detection and identification of microorganisms is blood culture, which can take up to 5 days to yield a …
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Klebsiella pneumoniae bloodstream infections in hospitalised children at Red Cross War Memorial Children's Hospital : 2006 - 2011
… pneumoniae (KP) is a significant paediatric bloodstream pathogen in children. There is little data about KP in South African children. The focus for the present study was to address this knowledge gap. Methods: This study addressed a retrospective case notes review on bloodstream Klebsiella …
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Most Effective Nursing Interventions to Prevent Central Line-Associated Bloodstream Infections: A Critical Review of the Literature
Nosocomial infections, otherwise referred to as hospital-acquired infections (HAIs), are defined by the Centers for Disease Control and Prevention (CDC) as infections that occur in association with devices used in medical procedures, such as catheters or ventilators (Centers for Disease Control and …
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Empowering Patients with Central Venous Catheters: Utilizing Evidence-Based Video-Assisted Education to Reduce Central Line-Associated Bloodstream Infections
… setting in which Central Line-Associated Bloodstream Infection (CLABSI) rates were rising. Pediatric oncology patients confer the highest risk of developing CLABSIs due to long-term CVC access, neutropenic effects of treatment regimens, and constant fluctuations between inpatient, …
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A ten-year review of ESBL and non-ESBL Escherichia Coli Bloodstream infections among children at a tertiary referral hospital in South Africa
Introduction: Bloodstream infection (BSI) is an important cause of morbidity and mortality in children (1). There are few descriptions of Escherichia coli (E. coli) BSI in children, particularly in Africa, yet E. coli is increasing in importance as a cause of antibiotic-resistant infection in …
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Defining the Aetiology and Antimicrobial Susceptibility Patterns of the Predominant Bacteria Associated with Bloodstream Infections at the Hospital for Tropical Diseases in Ho Chi Minh City, Vietnam
Bloodstream infections (BSI) are among the most common critical diseases that require intensive care and continuous surveillance. According to many multinational antimicrobial resistance surveillance schemes, Asia represents a substantial reservoir of clinically relevant antimicrobial resistant …
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Preventing and Reducing CLABSI with Daily 2% CHG Wipes
… project aims to decrease central line associated bloodstream infections in pediatric patients my microsystem hospital. The process begins re-enforcing daily CHG (2% Chlorhexidine Gluconate) wipes to 100% compliance rates on our patients with central lines tailored to their age and body weights. …
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Float Nurses’ Association with Nurse Sensitive Indicators: A Cross-Sectional Study
… Injuries (HAPI), Central Line-Associated Bloodstream Infections (CLABSI), and Catheter-Associated Urinary Tract Infections (CAUTI). Data was collected from 25 critical care and medical/surgical units across three hospitals from April 2023 to April 2024, utilizing the National Database for …
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Increasing Chlorhexidine (CHG) Daily Bathing Compliance
… to reduce and prevent central line associated bloodstream infections (CLABSIs) and catheter associated urinary tract infections (CAUTIs). These hospital-acquired infections (HAIs) plague and complicate treatments for critically ill patients in the acute care setting. CLABSIs and CAUTIs increase …
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Genetic and phenotypic diversity of bloodstream associated Staphylococcus epidermidis isolates obtained from private and public hospitals in South Africa
… is a commensal bacterium commonly implicated in bloodstream infections. Most S. epidermidis infections are acquired in hospitals and are associated with the use of medical devices. In contrast to its more virulent relative Staphylococcus aureus, S. epidermidis is often overlooked and regarded as …
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3D printing in Clinical Diagnostics: A Versatile Tool to Develop Testing Devices for the Diagnosis of Infectious Diseases
… establishes a proof-of-concept AST platform for bloodstream infections by sensing and monitoring the growth and antibiotic susceptibility of E. coli. Finally, I show the utility of 3DP in clinical diagnostics through the rapid development of a custom 96-well plate platform; microbial containment …
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Institutional and Patient Level Predictors of Multi-Drug Resistant Healthcare-Associated Infections
Healthcare-associated infections (HAI) caused by multi-drug resistant organisms (MDRO) are an important patient safety concern resulting in a substantial financial and clinical burden. This dissertation aims to contribute to the evidence base on institutional and patient level factors that predict …
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Epidemiology of Staphylococcus aureus bacteraemia at a tertiary children's hospital in Cape Town, South Africa
… important pathogen in paediatric patients with bloodstream infections. The epidemiology of S. aureus bacteraemia (SAB), however, has not been well documented in children in South Africa. Methods: A retrospective study was conducted at a children's hospital in Cape Town, South Africa, to …
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Alternative Carbon Utilization As A Virulence Determinant For Candida Albicans
… pathogen capable of causing a variety of mucosal infections and the life-threatening disseminated candidiasis. Systemic <em>C. albicans</em> infections are a serious and growing issue; the fungus is the fourth most common cause of nosocomial bloodstream infections which has a mortality rate …
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A genomic investigation into gastrointestinal antimicrobial resistance and clinical infection in patients undergoing transplantation
Globally, antimicrobial-resistant bloodstream infections (AMR-BSIs) claim 1.5 million lives annually. High-resolution sequencing data allows us to derive novel insights into AMR-BSIs. Immunosuppressed patients have a disrupted gut microbiome; therefore, transplant recipients provide an ideal …
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Speaking Up is Hard to Do:What Can Management Do to Help When Patient Safety is on the Line?
… to prevent and reduce central line-associated bloodstream infections (CLABSIs). Collectively, these studies find that healthcare organizations can successfully facilitate speaking up by implementing organizational and management practices that 1) emphasize the importance of speaking up with …
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Development and evaluation of novel antimicrobial solutions against biofilms and planktonic microbial growth
… a direct route for medical support into the bloodstream. However, when CVCs become colonized by microorganisms, this direct route into the bloodstream can often result in catheter related bloodstream infections (CRBSIs). These infections can be enormously costly,i ncreasing hospitalization …
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The Relationship Between Biofilm Production and Human Respiratory Cell Attachment and Invasion by Acinetobacter Baumannii
… bacterial pathogen that causes many nosocomial infections in immunocompromised individuals. Common infections include catheter-associated urinary tract infections, ventilator-associated pneumonia, skin and soft tissue infections, and bloodstream infections that often lead to septicemia. …
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