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Showing 1 to 20 of 63 for “"Blood--Coagulation"”.
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NMR investigations of blood coagulation: Conformational changes of membrane bilayers and proteins in blood coagulation
… investigate important interactions involved in blood coagulation. Structural and dynamics data of Ca2+-induced clusters of phosphatidylserine in membranes, important in blood clotting, is investigated using isotopically 13C, 15N-labeled phosphatidylserine in lipid bilayers. Finally, backbone …
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Blood Coagulation Factors in the Goat
Made available in DSpace on 2014-12-11T21:33:46Z (GMT). No. of bitstreams: 1 7317492.pdf: 3950835 bytes, checksum: aac9b310e4a495269ac3a7fc504c0c6b (MD5) Previous issue date: 1973
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Blood coagulation reactions on nanoscale membrane surfaces
Blood coagulation requires the assembly of several membrane-bound protein complexes composed of regulatory and catalytic subunits. The biomembranes involved in these reactions not only provide a platform for these procoagulant proteins, but can also affect their function. Increased exposure of …
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Contribution of different types of phospholipids in blood coagulation
… become activated and proper interaction of blood clotting proteins with membranes of activated platelets is essential for maintaining a balanced hemostasis. Hemophilia and thrombosis are the two extremes of an imbalanced hemostasis where patients with hemophilia suffer from severe bleeding …
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The Biochemical Pathway Leading to Lpa Generation Upon Blood Coagulation
… pathway responsible for LPA production during blood clotting is not fully understood. We have purified a phospholipase A<sub>1</sub> (PLA<sub>1</sub>) from thrombin-activated human platelets using sequential chromatographic steps followed by fluorophosphonate‑biotin affinity labeling and …
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The regulation of blood coagulation by high-density lipoprotein particles
… function in the reverse cholesterol transport. Blood coagulation is activated in response to tissue damage and involves a series of enzymatic protein complexes that assemble on the surface of anionic phospholipids, e.g. activated platelets. Lipoproteins contain a phospholipid surface, which may …
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Towards atomistic characterization of blood coagulation proteins by NMR spectroscopy
Proteins involved in the blood coagulation cascade are of vital biomedical importance, and most essential blood-clotting reactions occur preferentially on phospholipid membranes. Understanding the interactions between the proteins and membranes involved in blood clotting is crucial to the continued …
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The tissue factor-factor VII(a) complex in blood coagulation
Initiation of the coagulation cascade in vivo is mediated by tissue factor (TF), which functions as the cell surface receptor and catalytic cofactor for factor VIIa (FVIIa), as well as the mediator for the autoactivation of factor VII (FVII) to FVIIa. Upon vascular injury, TF is exposed to the …
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Comparisons among genetically diverse lines of chickens for blood coagulation factors
Blood coagulation time was determined in five genetically diverse lines of chickens by the capillary tube method. Significant differences were found among lines for coagulation time suggesting genetic influences on this characteristic in chickens. Heritability of blood coagulation as estimated by …
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Blood coagulation properties in hibernating and non-hibernating American bullfrogs (Lithobates catesbeianus)
1 PDF file (viii, 67 pages)
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Lipoids and blood platelets with reference to blood coagulation and the hemorrhagic diseases
… concerning the role of lipoids and platelets in blood coagulation and in the hemostatic mechanisms in health and disease. Analysed components are studied in artificial clotting systems, especially a two-stage thrombin- forming system. Some 86 cases of bleeding disorders, 32 new born normal …
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Characterization of OmpT: An outer membrane vesicle protease Escherichia coli that attenuates blood coagulation.
… for hemorrahagic colitis, renal failure, bloody diarrhoea, hemolytic uremic syndrome, thrombocytopenia, hemolytic anemia and other systemic problems. E. coli O157:H7 is responsible for outbreaks of Enterohemorrhaghic E. coli infections and causes significant mortality and morbidity …
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Haemophilia: a sketch of our present knowledge of the disease, with results in eight cases of the effect of normal serum on the blood coagulation time
1. The transmission of the disease in all the cases is according to the usual rule - through the female line.
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The effect of psychological stress procedures on the coagulation system in the albino rat
Research dealing with changes in the blood coagulation system as a result of psychological stress procedures appears to be rather limited. Apart from the work of Cannon about forty years ago, and more recent clinical observations, the accumulated experimental findings in this area are few. However, …
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Effects of algal docosahexaenoic acid in an extruded cat diet on nutrient digestibility, fecal characteristics and metabolites, and blood coagulation parameters and fatty acid profiles of plasma and red blood cell membranes
… algal-DHA (aDHA) on plasma fatty acid profile, blood coagulation parameters, and apparent total tract nutrient digestibility (ATTD) by adult cats. Three diets were formulated to contain 10% poultry fat alone (control; CT) or 8% poultry fat with a 2% inclusion of fish oil (FO) or a 2% inclusion …
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Studies on formation and stabilization of pathological thrombi in vivo
… activation receptors and the contact system of blood coagulation in such pathological conditions was investigated in mice.
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Multiplex analysis of protein-lipid and protein-membrane protein interactions utilizing silicon photonic microring resonators
… study protein-lipid interactions that govern the blood coagulation cascade. To accomplish this, nanodiscs were integrated with silicon photonic microring resonators. Nanodiscs are easy to assemble, nanometer scale lipid bilayer discs which offer a high degree of control over lipid and membrane …
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Biological Functions of ribonuclease 1 and angiogenin
… study of these enzymes. Extracellular RNA drives blood coagulation, which is preventable by administration of RNase A. In Chapter 2, I demonstrate that loss of RNase 1, a nonspecific and extracellular ptRNase similar to RNase A, results in the potentiation of blood coagulation by activation of …
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