Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"Blood oxygenation level dependent"”.
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Correcting the variations of bold signal due to susceptibility-induced magnetic field gradients and its application
… magnetic resonance imaging (fMRI) using blood oxygenation level dependent (BOLD) signals is a tool that is currently used in many cognitive neuroscience studies. However, many studies do not consider susceptibility-induced magnetic field gradients. Susceptibility-induced magnetic field …
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A multimodal investigation in eye movements
… BNCs. Functional activity is assessed using the blood oxygenation level dependent (BOLD) percent signal change. Task-modulated coactivation is assessed using an ROI-based task modulated coactivation analysis that reveals significant correlation between ROIs.
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Examination of susceptibility effects on functional and dynamic magnetic resonance imaging
… drives certain contrast mechanisms including blood oxygenation level dependent fMRI. The two projects in this work look at the effects of inhomogeneity on functional and dynamic MRI. We simultaneously acquired functional and dynamic MRI (Simulscan) of natural un-cued swallows. Work was done to …
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Advances in functional magnetic resonance imaging to facilitate brain research
Probing brain functions at laminar and columnar level provides opportunities in understanding local and remote neural circuits that are critical for cognition and behaviors. High field functional magnetic resonance imaging (fMRI) based on blood oxygenation level dependent contrast (BOLD) is one …
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Expanding the role of functional mri in rehabilitation research
… magnetic resonance imaging (fMRI) based on blood oxygenation level dependent (BOLD) contrast has become a universal methodology in functional neuroimaging. However, the BOLD signal consists of a mix of physiological parameters and has relatively poor reproducibility. As fMRI becomes a …
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A functional MRI study of the distributed neural circuitry of learning and reward
… magnetic resonance imaging (fMRI) with blood oxygenation level dependent (BOLD) contrast was then used to evaluate the brain activation in response to behaviorally characterized electrical stimuli. High resolution anatomical images revealed that subjects with electrode tips positioned …
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Subject and group level changes and comparison in functional connectivity under low vs. high cognitively demanding naturalistic viewing conditions using fmri
… and implements statistical methods applied on Blood Oxygenation Level Dependent (BOLD) signals. The conventional task based designs are very specific and may not reflect day to day activities. The two task conditions in this study are watching a movie called INSCAPE with low cognitive load and …
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The BOLD MRI response of the brain to alterations in arterial blood pressure
The impact of blood pressure changes on cerebral blood flow is an important area of investigation. The cerebral autoregulation mechanism acts to maintain blood supply to the brain, despite changes in blood pressure. Blood flow alterations are closely linked to neuronal activation, and this activity …
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Novel Functional Magnetic Resonance Imaging Analysis Approaches for Investigations of the Dynamics of Resting-State Functional Connectivity
Spontaneous fluctuations of blood-oxygenation level-dependent functional magnetic resonance imaging (BOLD fMRI) signals are highly synchronous between brain regions that serve similar functions. This provides a means to investigate functional networks of the human brain; however, most data analysis …
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Investigating neural correlates of stimulus repetition using fMRI
… effects in the human brain. However the Blood-Oxygenation Level-Dependent (BOLD) signal measured by fMRI is far removed from the electrical activity recorded from single cells in animal studies of repetition effects. Despite that, there have been many claims about the neural mechanisms …
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Simultaneous DTI and rs-fMRI using the navigated diffusion sequence
Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI) experiments are normally performed separately. The idea of extracting inherently co-registered activation/connectivity maps and diffusion parameters has resulted in efforts to …
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Not All Adversity is Created Equal: Differential Associations of Adversity Profiles with Adolescent Cognitive Control and Psychopathology
… and 4, adolescents' behavioral performance and blood-oxygenation-level-dependent response during a cognitive control task were measured. Two years later, at Time 5, adolescents and their caregiver reported on adolescent internalizing and externalizing symptomatology. Using latent profile …
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Biophysical modeling of hemodynamic-based neuroimaging techniques
… Magnetic Resonance Imaging (fMRI) based on the Blood Oxygenation Level Dependent (BOLD) response has become the method of choice for exploring brain function, and yet the physiological basis of this technique is still poorly understood. Despite the effort, a detailed and validated model relating …
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Dynamic Magnetic Resonance Imaging for Tumor Prognosis
… and carbogen inhalation), which improve tumor oxygenation during radiotherapy and chemotherapy, have been used in clinical trials. There is increasing demand for tumor prognostic information in the clinical setting. So far, increasing clinical data have indicated that poorly oxygenated tumors …
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Towards imaging cerebral microvascular blood flow using MRI
… capillaries and venules, in which the blood flow velocity is slow (≤ 2 cm/s). The hemodynamic signals, blood oxygenation-level dependent response, cerebral blood flow, cerebral blood volume and cerebral metabolic rate of oxygen are the common surrogate markers to detect brain neural …
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An investigation of the integrity of two components of the cerebellar neurocircuitry involved in classical eyeblink conditioning in children prenatally exposed to alcohol: a magnetic resonance spectroscopy and functional magnetic resonance imaging study
… cortex, respectively. We found that higher levels of prenatal alcohol exposure were associated with lower levels of both N-Acetylaspartate (NAA) and choline-containing metabolites, and with higher levels of glutamate plus glutamine (Glx), suggesting a disruption of the glutamate-glutamine …
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Univariate and Multivariate fMRI Investigations of Delay Discounting and Episodic Future Thinking in Alcohol Use Disorder
… mapping of DD routinely uses modalities such as blood-oxygenation-level-dependent functional magnetic resonance imaging (BOLD fMRI). However, the extent to which these brain activation maps reflect the characteristics of impulsive behavior has not been directly studied. To examine this, we used …
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Parietal dysfunction in children with prenatal alcohol exposure
… by prenatal alcohol exposure. Functional domains dependent on intact parietal functioning, including mathematical and visuospatial ability, have been consistently implicated in fetal alcohol spectrum disorders. This thesis examines, in children, using blood oxygenation level dependent (BOLD) …
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Bridging Mri Reconstruction Across Eras: From Novel Optimization Of Traditional Methods To Efficient Deep Learning Strategies
… over conventional methods. Furthermore, the blood oxygenation level dependent (BOLD) signal analysis of our proposed method provided meaningful sensitivities, with similar activation patterns and extent to the expected baselines.
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Cardiorespiratory fitness as a modulator of hippocampal subfield structure and function in cognitive aging
… humans. Age-related impairment in hippocampally-dependent cognition emphasizes the importance of identifying modulators of hippocampal plasticity. Critically, studies in older adults have demonstrated that greater cardiorespiratory fitness (CRF) is associated with greater volume of the …
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