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Showing 1 to 11 of 11 for “"Blood groups"”.
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The Effects of Selection of Blood Groups in Pigs
Made available in DSpace on 2015-05-12T22:37:25Z (GMT). No. of bitstreams: 2 license.txt: 4848 bytes, checksum: 96035ab3f5e1c23cc7138a224ce498bd (MD5) 7212191.PDF: 5338252 bytes, checksum: 7aec34f74b5c2dd234b554ac4f79419f (MD5) Previous issue date: 1971
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Blood groups and the rise of human genetics in mid-twentieth century Britain
This dissertation reconstructs how blood groups were made into pre-eminent objects of human genetic research and powerful markers for producing human biological difference. By tracing the ways in which three British laboratories became international centres for blood-group genetic research, it also …
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Next Generation Sequencing-Based Genotyping of Human Blood Groups: FY, JK and ABO Genes
Serological discrepancies in matching blood group antigens between donors and patients for blood transfusion may lead to alloimmunisation, especially in multiply transfused patients. Blood group genotyping (BGG) has contributed in reducing this issue. ABO, Fy and Jk antigens are among those to be …
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A study of selected antineoplastic, antibiotic, and corticosteroid drugs in intravenous admixtures
… or rate of administration. Frequently, adequate blood and tissue levels needed to eradicate many serious infections can be reached only by this route. Intravenous therapy is an especially appropriate method when the use of the oral tract, for one reason or another, cannot be used.</p><p>The …
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A genome-wide association study in chronic thromboembolic pulmonary hypertension and the ADAMTS13-VWF axis
… CTEPH patients including its relationship to ABO blood groups and ADAMTS13 genetic variants. Plasma ADAMTS13 levels are markedly reduced in CTEPH. This is independent of pulmonary hypertension, disease severity or systemic inflammation. Plasma VWF levels were confirmed to be markedly increased in …
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Genetic Characterisation of Human ABO Blood Group Variants with a Focus on Subgroups and Hybrid Alleles
ABO is the most important blood group system in transfusion medicine and transplantation immunology. The ABO blood groups differ by the presence or absence of antigens on RBCs and antibodies in plasma. Accurate determination of ABO status is critical. Genomic typing can increase the precision of …
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Studies on the genetic basis of Pk, P and P1 blood group antigen expression
The clinically important carbohydrate P/GLOB blood group systems and collection give rise to both common (P1, P2) and rare (p, P1k, P2k) blood group phenotypes. The associated antibodies are implicated in severe transfusion reactions and recurrent spontaneous abortions. The aim of this study was to …
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Beyond the rare blood group Vel, uncovering the functions of SMIM1 in blood and in other organs
Vel is a universal antigen present on the red blood cells (RBCs) membrane, which defines the Vel-blood group system. The identification of Vel-encoding gene, SMIM1, suggested that this is a regulator of erythropoiesis. Its role in RBCs and potential role in other cells, however, remains largely …
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Epidemiological studies of whole blood donation in the UK: Donor safety and retention
Background NHS Blood and Transplant (NHSBT), the sole provider of blood to the National Health Service (NHS) in England, UK, must ensure a safe and sustainable supply of blood, whilst protecting donor health and wellbeing. Objectives The primary objective of this thesis is to advance the evidence …
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Entwicklung neuer Markersysteme für die ancient DNA Analyse
Die Rekonstruktion der Lebensbedingungen von Menschen vergangener Zeiträume ist eines der Desiderate der Prähistorischen Anthropologie. Ein wichtiges Quellenmaterial stellen in diesem Zusammenhang die körperlichen Überreste vor- und frühgeschichtlicher Menschen dar. Ihre Analyse bietet Zugang zu …
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ΓΕΝΕΤΙΚΟΣ ΠΟΛΥΜΟΡΦΙΣΜΟΣ ΕΝΖΥΜΩΝ ΤΟΥ ΠΛΑΚΟΥΝΤΑ
… WERE ALSO EXAMINED IS SAMPLES OF CORD BLOOD. A) A NEW APH VARIANT WAS DESCRIBED. B) THE PERCENTAGES OF G-GPD DEFICIENCY DIFFER SIGNIFICANTLY IN VARIOUS DISTRICTS. C) A NEW LDH VARIANT WAS FOUND AND PERHAPS IT REPRESENTS A NEW MUTATION. D) THE THREE LOCI (ESD, GOTS, GOTM) WERE SCREENED …