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Showing 1 to 6 of 6 for “"Blood flow dynamics"”.
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Oscillations in microvascular flow : their relationship to tissue oxygenation, cellular metabolic function and their diagnostic potential for detecting skin melanoma - clinical, experimental and theoretical investigations
… growth. This leads to irregular patterns of blood flow which are spatially and temporally heterogeneous. Many investigations into the characteristics of tumours are invasive and performed on animal models. However, continuous technological and theoretical advancement is leading to the use of …
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Towards Understanding Nanoparticle Uptake by the Liver: The Role of Flow Dynamics, Organ Microarchitecture and Cellular Phenotype
… modeling and experimental methods, we show that blood flow dynamics, organ microarchitecture and cellular phenotype govern the off-target accumulation of nanoparticles. These results suggest new strategies to improve nanoparticle delivery and in Aim 3 we demonstrate that manipulation of these …
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Numerical methods for computationally efficient and accurate blood flow simulations in complex vascular networks: Application to cerebral blood flow
It is currently a well-established fact that the dynamics of interacting fluid compartments of the central nervous system (CNS) may play a role in the CNS fluid physiology and pathology of a number of neurological disorders, including neurodegenerative diseases associated with accumulation of waste …
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Leveraging Right and Left Ventricular Coupling for Optimization of Mechanical Circulatory Support
… price in that coupling evolved to optimize blood flow dynamics and the complex interplay between individual cardiovascular components and interposing organs like the lung. Disrupting native coupling with mechanical support risks decompensation if the heart and lung cannot tolerate these …
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Application Of In Vivo Flow Profiling To Stented Human Coronary Arteri
… applies in vivo technique for profiling hemodynamics and wall shear stress (WSS) distribution in human coronary arteries. The methodology involves fusion of 2D Intra Vascular Ultra Sound and Bi-plane angiograms to reproduce the 3D arterial geometry. This geometry is then used in a …
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Cerebral blood flow in the non-human primate : an in vivo model and drug interventions
Cerebral blood flow dynamics is an essential component for preserving cerebral integrity. Cerebral blood flow abnormalities are often seen in patients with central nervous system pathologies such as epilepsy, migraine, Alzheimer's Disease, vascular dementia, stroke, and even HIV/AIDS. There is …