Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Blood cell development"”.
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Finding lncRNAs in bone marrow and fetal liver erythroid progenitor cells in mice
Red blood cell development is crucial to the survival of all mammals and occurs primarily in the liver during embryogenesis and then in the bone marrow during adulthood. In spite of the different microenvironments of the liver and bone marrow, current research shows that the majority of …
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Functional Investigation of Genetic Determinants of Red Blood Cell Traits
… thousands of genetic loci associated with blood cell traits. However, the identification and interpretation of candidate causal variants and genes remain challenging. With increasing power to detect genetic associations, many loci reveal multiple statistically independent signals, which - …
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Genetic programming of human iPSC-derived macrophages provides a tool to study the Erythroblastic Island niche in vitro
… techniques, such as induced pluripotent stem cells (iPSCs), represents a valuable tool in the macrophage field. As a proof of principle, we used a human iPSC-line that was targeted in the safe harbour AAVS1 locus to express the fluorescent protein ZsGreen constitutively (SFCi55-ZsG). We …
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REGULATION OF Fas-MEDIATED APOPTOSIS BY THE Fas ANTI-SENSE NON-CODING RNA "Saf"
In multicellular organisms, cell growth and differentiation is controlled in part by apoptosis. One major apoptotic pathway is triggered by Fas receptor (Fas)-Fas ligand (FasL) interaction. Resistance to Fas-mediated apoptosis is regulated through the production of a soluble Fas isoform (sFas), …