Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 9 of 9 for “"Blood biomarker"”.
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Applications of blood biomarkers of traumatic brain injury across the severity spectrum---a focus on pathophysiological mechanisms
… However, a growing body of evidence suggests blood biomarker analysis may be a useful tool to aid in the elucidation of important pathophysiological mechanisms across a range of severities in human TBI. OBJECTIVE. The aim of this thesis was to use blood biomarkers as a tool to advance …
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Visual Outcome Measures of Remyelination and Neuroprotection in Multiple Sclerosis
… visual acuity, colour vision, oculometry, and blood biomarker measures on approximately 180 people with MS and 30 healthy volunteers across three clinical studies. My findings suggest that there is no single visual outcome measure that should be used in isolation for MS clinical research and …
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Defining the genetic and molecular pathways underlying motor neuron degenerative diseases
… Unfortunately, there are currently no universal biomarker assays or disease-modifying therapies available for the majority of affected individuals, primarily due to a lack of understanding of the pathomolecular causes of disease. The identification of disease-associated genes provides a direct …
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The effects of physical function and genetics on cognition and blood biomarkers in individuals at-risk for Alzheimer’s disease and related dementias
… has been identified as a novel diagnostic ADRD biomarker which needs further research to examine associations with risk factors. Therefore, the aims of this investigation were (1) Understand if higher physical function clusters produce better cognitive outcomes and blood biomarker profiles …
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SUBCONCUSSIVE HEAD IMPACT EFFECT ON PLASMA EXPRESSION OF S100-BETA AND PINCH PROTEINS IN COLLEGIATE FOOTBALL PLAYERS
… subconcussive impact effect by comparing the biomarker levels at pre and post full-gear practice, followed by examining the relationship of head impact magnitude and frequency of on acute increases in S100β and PINCH levels and symptom score. Hypotheses for the first aim were that there would …
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Diagnostic Methods in Traumatic Brain Injury
… quantify DAI. Study III tested whether a novel blood biomarker, neurofilament light (NFL), could identify DAI, and study IV tested whether a microwave technology (MWT) device, designed for use also in a prehospital setting, could detect intracranial hematomas. Patients and methods: In study I, …
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Quality of life, Biomarkers, and Involvement of Ghrelin in Women with Breast Cancer
… any neoplastic background, changes in serum biomarkers of women with BC and to detect the impact of the disease on these biomarkers at the beginning of the disease before treatment started and then again 12 months later following treatment for the cancer and the role of ghrelin hormone in BC …
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Digestibility of calcium and phosphorus and effects of microbial phytase in diets fed to growing pigs or gestating sows
… sows affect the ATTD and retention of Ca and P, blood Ca and P, serum concentrations of hormones, and blood biomarker for bone synthesis and resorption. Sows in late-gestation were fed one of 4 experimental diets containing 25, 50, 75, or 100% of the requirement for Ca with a constant level of P. …
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Imaging Post-Infarct Myocardial Inflammation with ⁶⁸Ga-DOTATATE PET/MRI and insights into COVID-19 associated myocardial injury
… as well as to identify potential systemic and blood biomarker correlates of myocardial <sup>68</sup>Ga-DOTATATE PET signal. Methods: In a prospective observational cohort study, participants with recent MI underwent hybrid <sup>68</sup>Ga-DOTATATE PET/MRI within 2 weeks of infarction …