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Showing 1 to 14 of 14 for “"Blood Damage"”.
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Untersuchungen zur Blutschädigung durch laminare Strömung im Couette-System
Blood damage of artificial systems within the circulatory system still remains a major problem despite of enormous research activities in this area. Forces acting on blood corpuscles due to non physiological flow conditions, partially in combination with artificial surfaces, are considered as main …
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A theoretical approach to the prediction of haemolysis in centrifugal blood pumps
… strongly depends on the extent to which they damage blood. The development of a theoretical pump evaluation model was performed in this study to facilitate an effective pump optimisation. The optimisation process seeks to maximise flow performance and minimise blood trauma which is primarily …
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Kenngrößenorientierte Beurteilung von Rotationsblutpumpen diagonaler Bauart mittels numerischer Strömungssimulation
… the flow phenomena within the implantable rotary blood pump “MikroDiagonalPump” (MDP) by means of Computational Fluid Dynamics (CFD). In the first part, a method has been developed to evaluate different pump geometries and impeller variations in a standardised and efficient way. The evaluation was …
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Numerische Simulation der Strömung in Miniaturkreiselpumpen zur Blutförderung
… lead to the development of a new generation of blood pumps with minimal size. This development is mainly focussed on hydraulic performance and biocompatibility. This thesis covers the assessment of computational fluid dynamics as a tool to investigate fluid dynamics and blood damaging effects …
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A novel magnetically levitated interior permanent magnet slice motor
… motor. This design is targeted for use as a blood pump in extracorporeal life support (ECLS) applications. A magnetically levitated blood pump reduces the risk of blood damage that frequently occurs at the blood seal in a conventional pump due to frictional heat generation.
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Design of Percutaneous Dual Propeller Pump to assist Patients with Single Functional Ventricle
… the TCPC is developed and studied. The designed blood pump is percutaneously inserted via the Femoral vein and deployed at the center of Total Cavopulmonary Connection (TCPC). The two propellers, each placed in the Superior Vena Cava (SVC) and the Inferior Vena Cava (IVC) are connected by a …
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Bluttraumatisierung bei der Passage zeitkonstanter und zeitvarianter Scherfelder
… in human circulation is limited by their reduced blood compatibility. This is mainly dependend on flow conditions and the contact to artificial surfaces. In blood pumps or artificial heart valves high fluid mechanical stresses are dominating. This thesis reports about a systematic damage …
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Erfassung der Hämolyse mittels optischer Reflexionsspektroskopie
The mechanical blood damage (hemolysis) is a critical fact of medical blood assisting devices. In order to minimize the physiological stress of the patients, the flow rate must be adapted in terms of hemolysis. In this dissertation a new method for a continuous detection of hemolysis is presented. …
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Extracorporeal Circulation: Effect of Long-Term (24-Hour) Circulation on Blood Components
Extracorporeal circulation damages blood and causes harmful side effects such as stroke and/or systemic inflammatory response in patients. Reactions of blood components to extracorporeal circulation include complement and inflammatory reactions, coagulation and thrombogenesis, frank hemolysis, and …
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Hemodynamic Optimization of a Passive Assist Total Cavopulmonary Connector for ages 1-20
… The 4-way connector was intended to channel the blood flow from the inferior and superior vena cava directly to the right and left pulmonary arteries. By creating a connector with proper hemodynamic characteristics, one can control the jet flow interactions between the inferior and superior vena …
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Extrakorporale Membranoxygenierung mit dem DeltaStream-System bei experimentell induziertem akutem Lungenversagen
… extracorporal circuit consisting of a diagonal blood pump and characterized by a significantly reduced foreign surface area and a decreased extracorporeal volume. We thus hypothesized that the DeltaStream-system may reduce contact activation of the blood resulting in less blood trauma. In …
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Homopolar bearingless slice motors with magnet-free rotors for extracorporeal life support
… is a medical therapy that uses an external blood pump and oxygenator to provide cardiac or cardiopulmonary support. One common system-related challenge is to reduce blood damage, e.g., hemolysis, which is primarily caused by the stress and heat from the pump impeller's bearing surface. …
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Application of passive flow control to mitigate the thromboembolic potential of bileaflet mechanical heart valves: an in-vitro study
… information was then used in numerical models of blood damage to predict the TEP of test heart valves using established platelet activation and platelet lysis parameters. BMHV leaflets were constructed using 3D printing technology with VGs based on micro-CT scans of a model BMHV leaflet. Two …
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Bearingless Slice Motor and 6-DoF Position Sensor for Extracorporeal Pump
… for the bearingless motor is an extracorporeal blood pump. Extracorporeal blood pumps are used to maintain blood flow as a temporary ventricular assist device and/or blood oxygenator. Bearingless pumps can help to avoid blood damage caused by friction and heat generation due to seals and …