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Showing 1 to 2 of 2 for “"Bisintercalation"”.
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Topologically constrained DNA intercalators: Synthesis and DNA binding studies
… 9-position and have been shown to bind to DNA by bisintercalation using absorption spectroscopy titrations, thermal denaturation studies, and viscometric titrations of both calf thymus DNA and closed circular supercoiled DNA. Macrocycle 31 dissociates 10 to 40 times slower from poly(d(A-T)) $\sb2$ …
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Novel bisnaphthalimidopropyl polyamine derivatives: their mode of action in a breast cancer cell system.
The synthesis and characterisation of novel bisnaphthalimidopropyl polyamine (BNIPP) derivatives has gained pace over the last couple of years, as they have enhanced aqueous solubility without loss of biological activity in contrast to parent bisnaphthalimide derivatives. Recent work has shown that …