Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 116 for “"Birth cohort"”.
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Ornithobacterium hominis isolates from a South African birth cohort
… however, this species is notably absent from cohorts based in the northern hemisphere. Recent microbiome data from the Drakenstein Child Health Study (DCHS) has shown that O. hominis is present in South Africa; however, there is a lack of microbiological data regarding this species in Africa. …
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Behavioural Difficulties in Early Childhood: Findings from a Longitudinal Birth Cohort
… Using the Growing Up in New Zealand birth cohort, behavioural problems were assessed when children were 2 years and 4.5 years using the preschool and standard parent-rated Strengths and Difficulties Questionnaire (SDQ), respectively. This thesis firstly investigated whether the SDQ …
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Latent class modelling of respiratory outcomes in a South African birth cohort
… wheezing patterns in LMICs (compared to a UK cohort) highlight the need for region-specific health policies and call for further study of long-term effects in diverse settings.
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Psychological trauma and posttraumatic stress disorder in a South African birth cohort study
… adverse maternal-child sequelae including poor birth outcomes and impaired infant neurodevelopment. Risk factors for psychological trauma exposure, and for subsequent PTSD, are likely to include environmental and genetic influences. Given the high burden of trauma and related disorders, the …
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Searching for Celiac Disease Screening-detected celiac disease in an HLA-genotyped birth cohort
… celiac disease in an HLA-genotyped birth cohort and to study systemic cytokines and bone mineral density (BMD) in these children. Methods: Children were HLA-genotyped at birth and offered screening at three and nine years of age by detection of tTGA in plasma using radioligand …
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Growth and determinants at two years of age in a South African birth cohort
… in children at 2 years of age in a South African birth cohort in a resource-limited region. Methods: Mother-child pairs enrolled in a South African birth cohort, the Drakenstein Child Health Study (DCHS), were followed from birth to two years. Comprehensive socio-demographic and psychosocial data …
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Comparison of growth curve models for assessing height in a South African birth cohort
Childhood malnutrition is a major concern in low- to middle- income populations. This dissertation uses longitudinal data on height measurements of babies between 0 and 4 years of age to construct growth curves, which serve as a tool for assessing the health and nutritional progress of children. We …
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Indoor air pollution and environmental tobacco smoke exposure in a South African birth cohort study
… Child Health Study (DCHS), a South African birth cohort study. The DCHS investigates the epidemiology and impact of early-life exposures on child health including lung disease. The study is set in a peri-urban poor community in the Western Cape, South Africa. Pregnant women were enrolled …
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Multi-state models for the analysis of Wheeze in a birth cohort of Western Cape children
… among various states of wheeze in children from birth to the age of three years. This study also aimed to investigate the association between possible risk factors for childhood wheezing and the estimated transition intensities. Methods The rationale for conducting the study, as well as the …
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Nasopharyngeal colonization dynamics with Streptococcus pneumoniae and associated antimicrobial resistance in a South African birth cohort
… NP swabs were collected every second week from birth through the first year of life from 137 infants who were immunized with 2+1 doses of PCV13. These were the first 137 infants enrolled in the cohort who had the most complete fortnightly NP sampling (defined as at least 23-26 fortnightly …
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Genetic and epigenetic associations with child development and mental health in a South African birth cohort
… Health Study (DCHS), an ongoing South African birth cohort study, provides an opportunity to investigate the associations of PRS, EA deviation, and MRS, with childhood developmental and mental health outcomes, in an ancestrally diverse study population. This doctoral project aimed to …
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Early socioemotional development: Investigating protective factors that support resilience in a South African birth cohort study
Globally, the prevalence of mental health challenges amongst children is increasing, raising significant concerns. Despite this, there remains a limited understanding of the protective factors that support resilience in children from low- and middle-income countries (LMICs). In high-risk contexts, …
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Characterization, drivers, and outcomes of picky eating behavior in the STRONG Kids 2 longitudinal birth cohort study
… Group (STRONG) Kids 2 (SK2) longitudinal birth cohort study is examining the various predictors of weight trajectory and dietary habits in young children, offering an opportunity to investigate the many factors involved in picky eating behavior from the ages of 12- to 48-months, …
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Prenatal alcohol exposure and the early neurodevelopmental outcomes of children in a South African birth cohort study
… Child Health Study (DCHS), a South African birth cohort. The specific objectives included: 1. a systematic review on the available longitudinal studies exploring the impact of PAE on language, speech and communication development (Chapter 3 Manuscript 1); 2. an exploration of the association …
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Ascertainment, prediction and implications of dementia diagnosis in a study of 'healthy' cognitive ageing: the Lothian Birth Cohort 1921
… chapter. The second chapter introduces the study cohort on which all of the studies included in the thesis are based – the Lothian Birth Cohort 1921 (LBC1921). The present thesis had three primary objectives. The first was to determine incident cases of dementia in a study cohort of oldest-old …
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Long-term effect of respiratory syncytial virus (RSV) infection on children: a prospective longitudinal birth cohort study in Bangladesh
… study, I assessed the respiratory health of a cohort of children aged 6-8 years with known RSV infection exposure during 0-59 days of life to evaluate the association between RSV infection and recurrent wheezing and asthma. I evaluated whether RSV infection during the young infant period (0-59 …
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Longitudinal colonisation by Streptococcus pneumoniae and nasopharyngeal microbial interactions in health and disease: a South African birth cohort study
… carriage over the first year of life, in a cohort of South African children, particularly after implementation of the 13-valent pneumococcal conjugate vaccine (PCV-13). The study will further elucidate the interaction of S. pneumoniae with other respiratory pathogens and how such …
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The Role of Streptococcus Pneumoniae Carriage on Wasting Among Vaccinated Gambian Infants: A Longitudinal Analysis of a Birth Cohort
… of data collected from 120 infants recruited at birth and followed up at regular intervals for two years. The data was collected in Rural Gambia between March 2013 and September 2015 as part of the Vaccination and Paediatric Microbiome Project. Nutritional status was classified using …
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Investigating associations between maternal mental health on wheeze through two years of age in a South African birth cohort study
… Child Health Study (DCHS), a prospective birth cohort study conducted in the Drakenstein region, a peri-urban region outside of Paarl in the Western Cape of South Africa. Pregnant women over 18 years old, between 20-28 weeks' gestation, living in the region were enrolled in a parent study, …
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A study of the association of prenatal inflammatory diet and adverse infant birth outcomes in a birth cohort in Uganda
Background: Low birth weight (LBW) and low infant lung capacity among others are risk factors for childhood and adulthood chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma. These respiratory diseases are among the leading causes of death and disability …
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