Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 59 for “"Biosafety"”.
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Biosafety Regulation: a comparative analysis of the South African and Ugandan experience
… provides a critical and comparative analysis of biosafety regulation in South Africa and Uganda. The overall objective of the study is to establish which country prescribes a more adequate regulatory regime. Biosafety regulation under international and regional law is the first key aspect that …
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An Analysis of the Biosafety System in Zambia -Regulatory framework, policies and procedures
… in 2003 and 2007, the country passed the Biosafety Policy and Biosafety Act respectively. In 2018, government stated that Zambia is a GM food free country. However, by July 2018, the National Biosafety Authority had authorised 24 applications regarding the placements of GM food products on …
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An Analysis of the Biosafety System in Zambia -Regulatory framework, policies and procedures
… in 2003 and 2007, the country passed the Biosafety Policy and Biosafety Act respectively. In 2018, government stated that Zambia is a GM food free country. However, by July 2018, the National Biosafety Authority had authorised 24 applications regarding the placements of GM food products on …
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An enquiry into biosafety regulations implementation in Kenya : perspectives and roles of scientists
… the development and subsequent implementation of biosafety regulations. Kenya's biotechnology innovation system has been driven largely by the contradictory framing of biotechnology as a scientific tool for innovation and international competitiveness on the one hand, and as a technology that has …
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Supranational organisations and cross-national policy convergence: the case of biosafety in southern Africa
… cross-national similarity or convergence of biosafety systems. This case study research was guided by the three factor conceptualisation of Per Olof Busch and Helge Jorgens (2005), which proposes harmonisation, diffusion and coercive imposition as three distinct international mechanisms …
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The Cartagena Protocol on Biosafety: A comparative analysis of the domestic implementation in South Africa and Uganda
… makes a comparative analysis of the current biosafety legislation in South Africa and the interim biosafety regulatory regime in Uganda. A set of common characteristics and components in biosafety regulatory systems with reference to related provisions of the Cartagena Protocol on Biosafety …
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Domestic Implementation of the Cartgena Protocol in Kenya and South Africa: A comparative analysis
… to what extent are current and proposed biosafety legislations in Kenya and South Africa consistent with or at variance with key provisions of the Cartagena Protocol on Biosafety (the Protocol)? The specific objectives of the study were: to provide an overview of international and African …
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Bridging gaps in synthetic biology oversight : iGEM as a testbed for proactive, adaptive risk management
… regulatory systems were adequate for monitoring biosafety in the early days of the emerging field, as synthetic biology advances, the fundamental differences in its logic structure are creating fissures in the oversight system. A continued reliance on increasingly incompatible mechanisms …
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Studying the biology of, and developing countermeasures to, a tick-transmitted hemorrhagic fever virus
… CCHF and work with live CCHFV is restricted to biosafety level 4 (BSL-4) laboratories. This measure, while preserving biosafety, has hampered progress towards developing medical countermeasures. Recombinant vesicular stomatitis viruses (rVSV) expressing foreign glycoproteins have shown promise …
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Construction of inducible expression systems for controlled transfer of Agrobacterium tumefaciens T-DNA in plant transient expression systems /
… are still desirable as a cheaper alternative. Biosafety concerns related to the use of recombinant agrobacteria in an industrial transfection process include possible transformation/transfection of unintended hosts or spread of the genetically modified agrobacteria in the environment. In this …
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Tackling the Bottlenecks in Translational Nanomedicine: Towards Precision in Size Control and Facile Nanoformulation
… system with fine particle size tuning and superb biosafety and ii) a polymeric nanoparticle system with instant nanoformulation capability and enhanced intracellular delivery efficiency. In the first system, a novel process-engineered fabrication method synthesizing sub-10 nm ultrasmall gold …
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Global Health Security Agenda Legal Landscape Assessment
… resistance, zoonotic diseases, national biosafety/biosecurity and immunization. The prevention action package included establishing a national laboratory system, strengthening real-time biosurveillance, advancing timely and accurate disease reporting and establishing a trained global …
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Implementation of the precautionary approach in the regulation of genetically modified organisms: an African context
… a manner as to enhance the credibility of their biosafety legislation, but still promote biotechnology, with a view of possible replication across Sub-Saharan Africa (SSA).
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Risk-Benefit Assessment of Pandemic Virus Identification
… development, critics raise concerns about biosafety and biosecurity risks. This thesis presents a comprehensive mathematical framework to evaluate the benefits, biosafety risks, and biosecurity risks associated with PVI research. Using a combination of mathematical modeling and expert …
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Improving point-of-care diagnosis of tuberculosis: development and evaluation of novel technologies
… specimen processing without the requirement of a biosafety cabinet. The chemiresistive sensor, which detects volatile organic compounds released by Mycobacterium tuberculosis in a patient's breath, demonstrated a high sensitivity (100%) and specificity (92%) for distinguishing patients with active …
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The production of a Crimean-Congo haemorrhagic fever virus diagnostic antigen in plants
… involve the use of live virus antigen, requiring biosafety level 4 (BSL4) conditions for safe handling. The development of a safer diagnostic reagent for detection of this disease is therefore desirable. This project involves the development of a recombinant CCHFV nucleocapsid protein (NP). The …
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Análise da aerodispersão de contaminantes em laboratórios de pesquisa com biossegurança
… are generated within research laboratories with biosafety level. The analysis were conducted using numerical simulations, with the computational fluid dynamics (CFD) technique. Three benchmarks, related to this class of problems, were used for CFD code validation. This thesis’ modeling assumption …
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Developing VHH-based tools to study Ebolavirus infection
… VHHs were found to neutralize Ebolavirus in both Biosafety Level 2 and 4 laboratory conditions. Ongoing experiments to address mechanism focuses on two aspects of neutralization: Cathepsin inhibition or NPC1-mediated inhibition. Finally, Chapter 3 discusses the overall landscape for Ebolavirus …
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