Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Bioprocess monitoring"”.
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Advanced Raman spectroscopy for bioprocess monitoring
… the lack of sensitivity of conventional Raman in bioprocess applications, the major drawback of this technique so far has been the disturbance of the broad fluorescence background especially in biological samples. The main objective of this thesis was to find solutions for increasing the limit of …
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Online Raman spectroscopy for bioprocess monitoring
Online monitoring of bioprocesses is essential to expanding the potential of biotechnology. In this thesis, a system to estimate concentrations of chemical components of an Escherichia Coli fermentation growth medium via a remote fiber-optic Raman spectroscopy probe was studied in depth. The system …
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Development of a regenerable glucose biosensor probe for bioprocess monitoring
… of enzyme-based biosensors for on-line bioprocess monitoring and control has been slowed by problems relating to the in situ sterilizability of the probe and the stability of the enzyme component. A novel technology is presented here which addresses both of these difficulties. The …
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Combining Chemometrics and non-target GC-IMS gas phase analysis for improved bioprocess monitoring
… technologies is an active area of research. In bioprocess monitoring, most established PAT focuses on the liquid broth. A potential addition to established PAT is the analysis of volatile organic compounds (VOC) including microbial VOCs (mVOC), in the fermentation headspace. The hypothesis was, …
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Mid-Infrared Integrated Devices for Optical Chemical Sensing
… were developed and tested for con- tinuous fluid monitoring. These showed good sensing capabilities for online, continuous and real-time liquid sensing in hard-to-reach locations. Next, this thesis presents the establishment and clinical testing of a novel method for continuous monitoring of the …
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A Bioelectrochemical Sensing System for Measuring Acidic Bioprocess Fermentation End Products
Monitoring is an important tool in the management of bioprocesses such as anaerobic digesters, wastewater treatment plants and bioelectrochemical systems. There are several important parameters which are considered for regular monitoring, including pH, temperature, conductivity, gas composition and …
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Design and Fabrication of Piezoelectric Sensors and Actuators for Characterization of Soft Materials
… measurement challenges associated with real-time monitoring of material compositional profiles using biosensors in practical biomanufacturing and bioprocessing formats, as insight into a material's composition (i.e., concentration of a given biologic within a material or product) provides …
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Bio-artificial liver support system : an evaluation of models used in demonstrating or improving metabolic and clinical efficacy
Acute liver failure (ALF) is a rare but devastating clinical syndrome with multiple causes and a variable course. The mortality rate is high. Orthotopic liver transplantation is the only therapy of proven survival benefit but the limited supply of donor organs, the rapidity of progression and the …