Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Biophysical Chemistry"”.
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Biophysical chemistry of lipopolysaccharide specific bacteriophages
Carbohydrate recognition is a ubiquitous principle underlying many fundamental biological processes like fertilization, embryogenesis and viral infections. But how carbohydrate specificity and affinity induce a molecular event is not well understood. One of these examples is bacteriophage P22 that …
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Theoretical advances toward understanding recent experiments in biophysical chemistry
… understand and guide recent experiments in biophysical chemistry. In Chapter 2, I consider a recent criticism of the Jarzynski equality, notably that a breakdown in the connection between work and changes in the Hamiltonian for time-dependent systems causes the Jarzynski equality to produce …
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Physico-Chemical Characterisation of Disease-Related Protein-Protein Interactions in Solution
… enable answering emerging questions in biophysical chemistry and medicine.
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Chemometrics and NMR spectroscopy for metabolomics analysis of neurological disorders
Contains fulltext : 94175.pdf (Publisher’s version ) (Open Access)
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Three-Dimensional Single-Molecule Localisation Microscopy and Visualisation Techniques
Quantitative imaging in complex biological samples requires techniques such as, super-resolution (SR) imaging to better understand the morphology and stoichiometry of proteins below the diffraction limit. 3 Dimensional (3D) SR tools such as the 3D double helix-point spread function (DH-PSF) and 3D …
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Anaerobic, NADH-Dependent Haem Breakdown in a Family of Haemoproteins
Many pathogens function by internalising the haem molecules of their host organism and breaking down the porphyrin scaffold to sequester the Fe$^{2+}$ ion. Typically, this breakdown mechanism is mediated by a haem oxygenase. However, a novel class of reaction has been discovered, which can be …
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Microfluidic formation of hierarchical micro and nano emulsions for biomedical applications
The self-assembly of proteins and peptides into complex supramolecular structures provides an important avenue in the development of materials for biomedical applications. In particular, the design and fabrication of protein and peptide-based hydrogels has emerged as an attractive route toward …
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Molecular Mechanisms of Protein Self-Assembly and Aggregation
In this thesis, we investigate the mechanisms driving the self-assembly of peptides and proteins using computational and theoretical tools, always validating our results with experimental measures when possible. In the first part, Chapters 2-5, we focus on the A$\beta$ system, a peptide whose …
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Advances in biophysical characterisation through micron scale flow engineering
… cells central to the majority of biochemical and biophysical processes that sustain life. Interactions between proteins and other biomolecules are crucial to a faultless execution of biological function, yet it has remained challenging to analyse these biomolecular interactions with current …