Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 662 for “"Biomolecules"”.
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The charge migration in biomolecules
The one-dimensional polyconjugated chains of biomolecules are chosen for study. The band theory of the pi-electrons in polymers is reviewed and the experimental results of electric conduction in biomolecular systems are discussed. The migation of charges, especially that of holes which is …
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Geometric Deep Learning for Biomolecules
Recent advancements in machine learning offer a promising pathway to deeper insights into biological phenomena. This manuscript explores the integration of geometric deep learning techniques to model biological structures. By embedding inductive biases based on geometry and physical laws, we aim to …
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Microcapillary membranes for purification of biomolecules
… has not yet been studied for separation of biomolecules. The aim of this thesis is to develop microcapillary membranes for proof-of-concept biomolecule separations through various chromatography module constructions, surface chemistries and matrix composition modifications. The …
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Protective antigen-mediated delivery of biomolecules
The intracellular delivery of therapeutic biomolecules such as oligonucleotides and proteins remains a key challenge today. Protective antigen, a naturally evolved protein translocase derived from Bacillus anthracis, has shown promise as a platform of protein delivery due to its ability to form a …
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Inducing Chirality in CdS Nanocrystals with Biomolecules
… interfacing between high-quality NCs and chiral biomolecules. Although ligand exchange with cysteine has been shown to induce chirality in CdE NCs, no prior studies have demonstrated the use of intrinsically chiral biomolecules, like peptides and proteins, to generate chiroptical responses in …
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Physical biology of biomembranes and biomolecules (PHYBIOM)
To study mechanical properties of red blood cells, the combination of an AC dielectrophoretic apparatus and a single-beam optical tweezers were used. The experiments were performed with high frequency (e.g. 10 MHz) below the second turnover point between positive and negative dielectrophoresis. The …
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Electric field-assisted immobilization and alignment of biomolecules
… to achieve immobilization and alignment of biomolecules on metal electrodes in a simple one-step experiment. Neither modifications of the biomolecule nor of the electrodes were needed. The two major electrokinetic effects that lead to molecule motion in the chosen electrode configurations …
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Microfabricated Acoustic Sensors for the Detection of Biomolecules
MEMS (Microelectromechanical Systems) acoustic sensors are a promising platform for Point-of-Care biosensing. In particular, piezoelectrically driven acoustic sensors can provide fast results with high sensitivity, can be miniaturized and mass produced, and have the potential to be fully integrated …
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Fluorogenic probes for live-cell imaging of biomolecules
… System to Quantify the Cytosolic Delivery of Biomolecules. Cytosolic delivery of large biomolecules is a significant barrier to therapeutic applications of CRISPR, RNAi, and biologics such as proteins with anticancer properties. In Chapter 4, I describe a new paired enzyme-probe system to …
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Synthesis of hydroxyapatite with adsorbed and intracrystalline biomolecules
Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Materials Science and Engineering, 1999.
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Submicron-resolution Photoacoustic Microscopy of Endogenous Light-absorbing Biomolecules
… labeling probes may disturb the function of biomolecules and may have an insufficient density. This dissertation aims to advance label-free OR-PAM to the subcellular scale.</p><p>The first part of this dissertation describes the technological advancement of PAM yielding high spatial …
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A study on possible interactions between biomolecules and nanoparticles
Along with the rapid growth of the nanotechnology, nanoparticles (NPs) have found many applications in commercial products. However, there are only a few studies on the toxicity and the environmental effects of NPs in biological systems. In the study described in this thesis, I have used …
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An investigation of radiolytic damage to biomolecules in foodstuffs
… by the attack of ‘OH radical on a range of biomolecules occurring in foodstuffs. This study Involves an investigation of radiolytically-induced chemical modifications arising from the Interaction of ‘OH radical with naturally occurring aromatic compounds in fruits and vegetables. High …
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Biomolecules that impact phenotypic transitions in fibroblasts and macrophages
<p>Macrophages and fibroblasts are intricately involved in many biological responses. The foreign body response (FBR) is orchestrated by macrophages, wherein the phenotypes of these macrophages exist plastically along a spectrum from M1, proinflammatory macrophages to M2a, anti-inflammatory, …
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Partitioning of biomolecules in two-phase aqueous micellar systems
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1995.
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Delivery of biomolecules into mammalian cells using anthrax toxin
The intracellular delivery of biomolecules into mammalian cells is a major challenge due to the plasma membrane, which acts as a barrier between the extracellular environment and intracellular components. Recently, a non-toxic delivery platform derived from anthrax lethal toxin has been developed …
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Dynamic complex smart colloids for the detection of biomolecules
… ideal sensing particles for aqueous sensing of biomolecules such as bacteria, oligonucleotide, antibodies and viruses. This thesis expands the applications of complex smart colloids as bioassays that can be potentially adopted in food and beverage industry, environmental monitoring and medical …
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