Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 93 for “"Biomechanical properties"”.
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Biomechanical properties of engineered collagen scaffolds
… and loaded in tension, and their mechanical properties were compared. It was found that non-crosslinked scaffolds experience an average increase in weight after hydration of 10,353%, compared to 7,265% for crosslinked scaffolds. Hyperelastic material parameters were determined by the …
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The biomechanical properties of the human vocal fold.
… in this thesis is the quantification of the biomechanical properties of the vocal folds. There is a major gap in knowledge relating to the elastic properties of the vocal fold as the only reliable apparatus available to determine these properties rely on dissecting the tissue out of …
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Characterizing Corneal Biomechanical Properties Using Dynamic Optical Coherence Elastography
… elastography (OCE) quantifies the tissue’s biomechanical properties through mechanical loading and imaging the tissue response using optical coherence tomography (OCT). Current techniques evaluating corneal stiffness do not account for the influence of key physiological factors on the …
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Assessing the Biomechanical Properties of Cornea using Optical Coherence Elastography
… development of measurement methods to assess the biomechanical properties of cornea based on low-coherence optical imaging, focusing on optical coherence elastographic techniques, to meet the growing demand for noninvasive high-resolution tissue characterization with improved diagnosis and …
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Neutrophil biomechanical properties and immune function in health and inflammatory disease
… function being intimately linked to cellular biomechanical properties (e.g. density, stiffness, morphology). This thesis analyses the intersection of immune cellular biomechanical phenotypes and their function. Specifically, it focuses on the role of neutrophils and LDGs in inflammatory …
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Experimental study and computational modelling of the biomechanical properties of arteries
… to track the deformation of biological tissue in biomechanical experiments. The study shows that the optical flow technique provides a good estimation of the strains for the constructed deformation images by comparing the results with those of the finite element (FE) models. The optical flow …
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The biomechanical properties of epithelial cells and tissue in two and three dimensions
… is needed of the mechanical forces and properties involved. Therefore, there is a drive to develop novel tools to accurately measure biomechanical properties at different spatial scales.<br/><br/>3D cell models are a useful method to understand the mechanical properties at cell and …
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The influence of hydrodynamics on the growth, erosion and biomechanical properties of Laminaria digitata
… such as growth, erosion and the mechanical properties of kelp has received some research, however, teasing apart the effect of waves and currents on the biology of kelp is unknown. Here a combination of field and laboratory experiments were conducted to establish the influence of wave and …
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Mechanical deformation of neutrophil into pulmonary capillaries induces cytoskeletal remodeling, pseudopod projection and changes in biomechanical properties
Neutrophils traversing the pulmonary microcirculation are subjected to mechanical stimulation during their deformation into narrow capillaries. To better understand the time- dependant changes caused by this mechanical stimulus, in the first part of the thesis, neutrophils were caused to flow into …
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The Evaluation of Usefulness of the FEA and Relationship Between Trabecular Microstructural and Biomechanical Properties In Human Femoral Head
… between trabecular bone microstructure and its biomechanical properties, the microimage-based FEA and the experimental test were performed in the same bone cores from the primary compressive trabecular system of human femoral head. Twenty-one human femoral heads were obtained from 11 patients …
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IN-VIVO SCLERAL AND CORNEAL BIOMECHANICS AS BIOMARKERS IN OPHTHALMIC PRACTICE
As the relationship between biomechanical properties and abnormal tissue mechanics become more and more apparent in the field of ophthalmology, demand for in-vivo determination of biomechanical properties have also increased. While devices like the Ocular Response Analyser (ORA) have made the …
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Coherence imaging technologies for the measurement of tissue and cell biomechanics
Biomechanical properties are important for living tissues and cells. They are indicators of functional changes and pathological variations in the micro-structure, such as during tumor development. The topic of this thesis falls at the intersection of biomechanics and optical imaging, and focuses on …
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Magnetomotive optical coherence elastography for biomedical applications
… a new non-invasive optical method for assessing biomechanical properties of tissues and cells in real time and with micron scale resolution, magnetomotive optical coherence elastography (MM-OCE). Biomechanical properties are important because they relate to the tissues’ state of health and they …
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Optimizing a scaffoldless approach for cartilage tissue engineering
… that construct confinement resulted in enhanced biomechanical properties in the direction orthogonal to the confinement surface, either by enhancing collagen organization or by increasing collagen production. Next, the effects of hydrostatic pressure at different timepoints, magnitudes, and …
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A Nanoindentation Device and the Scale-Dependent Mechanical Properties of Native and Decellularized Liver Tissue
… as a scaffold for new cells. Characterizing the biomechanical properties of these scaffolds is important due to the mechanosensitivity of many cell types. In addition, in the emerging field of multi-scale modeling an effort is being made to integrate the small fundamental scales with the large …
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Heartbeat Optical Coherence Elastography: A Method for Passive Biomechanical Assessment of the Cornea
In this dissertation, the biomechanical properties of the cornea are explored using a novel, completely passive, biomechanical analysis technique termed heartbeat optical coherence elastography (Hb-OCE). This technology enables mechanical characterization of the cornea with applications in disease …
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THE IMPACTS OF CLIMATE AND THE ENVIRONMENT ON HUMAN SKELETAL MORPHOLOGY DURING THE HOLOCENE IN NORTH CHINA A
… body size and shape, entheseal expression and biomechanical properties of long bones to investigate: 1.) temporal patterns in postcranial dimensions, stature and body mass; 2.) regional differences between the northern and southern Chinese in body size and body/limb proportions; and 3.) …
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Characterization and Modeling of the Human Mouth Space for the Informed Design of Intraoral Wearable Human-Computer Interfaces
… mouth, predicting key volumes, dimensions, and biomechanical properties based on a few easily obtainable exterior measurements. The outputs of the model can inform the physical and material properties of the intraoral wearable design, saving the expense, difficulty, and intrusiveness of …
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Single Cell Biomechanical Phenotyping using Microfluidics and Nanotechnology
… is accompanied with alterations in the cell biomechanical phenotype, including changes in cell structure, morphology, and responses to microenvironmental stress. These alterations result in an increased deformability of transformed cells and reduced resistance to mechanical stimuli, enabling …
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Mechanical Simulation of Articular Cartilage Based on Experimental Results
… in order to predict articular cartilage (AC) biomechanical properties before and after growth. Previous research has noted limitations in the CGFEM such as model convergence with growth periods greater than 12 days. The main aims of this work were to address these limitations through (1) …
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