Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Biomathematics"”.
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Computer Modeling of Cardiac Electrical Activity by Polarcardiogram Patterns
<p>The objective of this thesis is to provide for the cardiologist polarcardiograms and additional diagnostic criteria which will enable him to diagnose heart disease more easily. Other contributions are those of: (a) providing a system of data acquisition and (b) analyzing Dr. Gordon Dower’s …
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Distribution of Maternal and Fetal Blood Flow within Cotyledons of the Sheep Placenta
<p>These studies explore the distribution of blood flow among small samples of placental tissue. Labeled microspheres (14 ± 1 pm) were Injected Into the left ventricle of six un-anesthetized ewes and Into the jugular vein of the fetus In utero. A total of 3,576 samples weighing 31. +11. (S.D.) mg …
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Development of a Mathematical Model of Renal Function for Clinical Application
<p>This model describes the orthoiodohippurate (OIH) distribution and clearance in the renovascular system. The model is described by five compartments: the blood, left and right kidneys, bladder and the red blood cell compartment. Data for these compartments, except the RBC compartment, are …
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Population models
<p>This thesis will examine mathematical interpretations of biological situations through the study of differential equations. It will first explore the interactions of the lynx and hare populations in Canada based on data retrieved by the Hudson Bay Company. The purpose of this study is to find a …
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Reaching Across the Divide: Tools for Bridging Structural and Viral Genomics Using a Combination of Biophysical Principles and Machine Learning
<p>Bacteriophages are the most ubiquitous biological entity on the planet, but most viruses found in nature cannot be cultured in the laboratory and encode genes whose sequences lack similarity with current nucleotide and protein databases. New predictive methods are thus necessary to determine the …
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Detecting and Evaluating Therapy Induced Changes In Radiomics Features Measured From Non-Small Cell Lung Cancer to Predict Patient Outcomes
<p>The purpose of this study was to investigate whether radiomics features measured from weekly 4-dimensional computed tomography (4DCT) images of non-small cell lung cancers (NSCLC) change during treatment and if those changes are prognostic for patient outcomes or dependent on treatment modality. …
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Assessing The Potential Clinical Impact of Variable Biological Effectiveness In Proton Radiotherapy
<p>It has long been known that proton radiotherapy has an increased biological effectiveness compared to traditional x-ray radiotherapy. This arises from the clustered nature of DNA damage produced by the energy deposition of protons along their tracks in medium. This effect is currently quantified …
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Improving Quantitative Treatment Response Monitoring With Deformable Image Registration
Quantitative imaging with 18F-FDG PET/CT has the potential to provide an in vivo assessment of response to radiotherapy (RT). However, comparing tissue tracer uptake in longitudinal studies is often confounded by variations in patient setup and potential treatment induced gross anatomic changes. …
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Computer-Aided Drug Discovery for Helicobacter pylori
<p>Helicobacter pylori is a high-priority drug-resistant pathogen and is currently the only bacteria considered to be a class I carcinogen and there is a critical need to identify novel chemical matter to treat H. pylori infections. Hp is responsible for greater than 60% of gastric cancer related …