Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 2098 for “"Biomarkers"”.
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Biomechanical biomarkers of cancer
Cancer is a major health issue within the UK, with more than one third of people developing it within their lifetime. As there are so many different types of cancer, a quick, accurate and non-obtrusive diagnostic technique would be beneficial. A potential diagnosis technique under investigation is …
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Biomarkers in IgA nephropathy
Contains fulltext : 140179.pdf (Publisher’s version ) (Open Access)
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Biomarkers of fat intake
The thesis reviews the previous use of biomarkers of fatty acid intake and concludes that there is a lack of supporting evidence from large randomized controlled trials (RCT) of sufficient duration for their use to be justified. The hypothesis that fatty acid biomarkers are robust indices of the …
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Behavioral biomarkers for calf health
Applied ethology is a diverse scientific field studying animals in confinement under human management. Data collection techniques including automated measures (e.g. activity monitors and environmental enrichment devices) and video recording systems aid in collecting animal behavior data while …
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Lipid Biomarkers for Marine Fungi
… be included in biogeochemical models. <br/>Lipid biomarkers can be used to assess microbial abundance and biomass due to their specificity and may be utilised to explore the viability and trophic dynamics of marine microbial communities. Although lipid biomarkers for fungi have been used in …
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Connectivity biomarkers in neurodegenerative tauopathies
… by disease. I investigate simple clinical biomarkers, showing that a two-minute test of verbal fluency is a potential diagnostic biomarker to distinguish between PD and PSP and that the ACE-R and its subscores could play a role in monitoring cognition over time in PD, PSP and CBS. I assess …
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Metabolomic Biomarkers for Colorectal Cancer
… for the development of clinically valuable biomarkers.
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Biomarkers identification in fibromyalgia syndrome
… the potential to identify new disease-specific biomarkers. Some purine nucleotide metabolism disorders such as myoadenylate deaminase (MAD) deficiency report symptoms similar to those seen in FMS. In consideration of what described above, we carried out a serum proteomic analysis of FMS patients …
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Oxidative stress biomarkers in dementia
Alzheimer’s disease (AD) is a devastating neurodegenerative disorder which is thought to affect 26.6 million individuals worldwide. There is growing concern over a worldwide dementia epidemic that is predicted to develop over the coming decades. The evidence thus far suggests that increased levels …
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Quantitative biomarkers for tissue characterization
This research proposes and examines noninvasive, quantitative techniques to characterize tissue. The primary metrics investigated include estimation of longitudinal speed of sound and shearwave elastography. Additional metrics investigated include bioimpedance and functional tests specifically for …
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Cardiac Biomarkers in Hyperthyroid Cats
… effects on the circulatory system. The cardiac biomarkers NT-proBNP and troponin I (cTNI) have proven useful in identifying cats with myocardial disease but have not been as extensively investigated in hyperthyroidism. Hypothesis: Plasma NT-proBNP and cTNI concentrations are higher in cats with …
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Recent Thymic Emigrants and their Biomarkers
… than mature peripheral T cells. Several biomarkers exist for these Recent Thymic Emigrants in CD4 positive cells, but not in CD8 positive cells. Therefore, human (CD8) RTEs are understudied, despite their critical role in the developing immune system, holding back research in the field of …
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Electrophysiological biomarkers in genetic movement disorders
BACKGROUND. Neurodegenerative diseases are diseases of the nervous system with progressive course leading to death. Treatment remains symptomatic. Development of neuroprotective agents has been hampered for various reasons. This includes the inability of making the diagnosis accurately early in the …
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Aggrecan fragments as biomarkers in osteoarthritis
… fluids by proteolytic cleavage can be used as biomarkers of ongoing processes. This thesis focuses on proteolytic degradation of the proteoglycan aggrecan with the overall aim to study the potential of aggrecan fragments as biomarkers in knee OA. Methodology/Principal findings: Using neoepitope …
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Malignant Glioma: Chemosensitivity testing and Biomarkers
Chemosensitivity testing and molecular biomarkers are commonly used methods during the management of several types of malignant tumours in routine clinical practice. The present work attempts to transfer the use of these two concepts to the management of malignant gliomas. Chemosensitivity testing …
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Blood Biomarkers of Presymptomatic Frontotemporal Dementia
… plasma-derived miRNAs and proteins as potential biomarkers of presymptomatic FTD. We utilised baseline data from six carriers and 17 controls, alongside longitudinal data from three timepoints with six carriers and 12 controls. Additionally, we optimised a pipeline to investigate plasma-derived …
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Imaging biomarkers for Duchenne muscular dystrophy
… patients. We propose the use of image-based biomarkers with suitable machine learning algorithms instead. We find that force-controlled (precise acquisition at a certain force) and force-correlated (acquisition over a force sweep) ultrasound helps to reduce variability in the imaging process. …
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Geochemical Significance of Biomarkers in Paleozoic Coals
Diese Arbeit analysiert extrahierbares organisches Material von 40 paläozoischen Proben mit dem Ziel, Einblicke in die biochemische Evolution der Landpflanzen zu gewinnen. Zusätzlich wird der Zusammenhang zwischen sauerstoffhaltigen Verbindungen und den nichtfunktionalisierten aromatischen …
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Eating Frequency, Disease-Related Biomarkers and Appetite
… regression was used to compare fasting plasma biomarkers and mean ratings of subjective appetite. A total of 15 participants completed both study phases (4 males, 11 females). Mean (± SD) age was 28.5 ± 8.70, and mean (± SD) BMI was 23.3 ± 3.4. There was a non-significant, but suggestive trend …
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